scholarly journals Anti–Vascular Endothelial Growth Factor Therapies as a Novel Therapeutic Approach to Treating Neurofibromatosis-Related Tumors

2010 ◽  
Vol 70 (9) ◽  
pp. 3483-3493 ◽  
Author(s):  
Hon Kit Wong ◽  
Johanna Lahdenranta ◽  
Walid S. Kamoun ◽  
Annie W. Chan ◽  
Andrea I. McClatchey ◽  
...  
2020 ◽  
Vol 21 (12) ◽  
pp. 1201-1207
Author(s):  
Maurizio Battaglia Parodi ◽  
Pierluigi Iacono ◽  
Stefano Da Pozzo

The therapeutic approach based on anti-vascular endothelial growth factor (anti-VEGF) molecules can be used to treat two important complications of retinal dystrophies: choroidal neovascularization and macular edema. The macular involvement in retinal dystrophies can lead to further visual deterioration in patients at a young age and already affected by functional limitations. The study reports the effect of anti-VEGF treatment in several subforms of retinal dystrophies, critically discussing advantages and limitations.


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