Abstract 1591: Identification and characterization of surface major vault protein on circulating tumor cells in patients with hepatocellular carcinoma

2016 ◽  
Author(s):  
Hyun Min Lee ◽  
Jae Won Joh ◽  
Hong Seo Choi ◽  
Won Tae Kim ◽  
Se Ri Seo ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Major Vault Protein ◽  
Identification And Characterization

Design of a Microfluidic Chip for Enrichment of Circulating Tumor Cells

2015 ◽  
Vol 645-646 ◽  
pp. 1320-1325
Author(s):  
Xi Xin Ling ◽  
Da Hai Ren ◽  
Zheng You
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Microfluidic Chip ◽  
Comsol Multiphysics ◽  
Enrichment Method ◽  
Cancer Metastases ◽  
Simulation Results ◽  
Novel Design ◽  
Identification And Characterization

Identification and characterization of CTCs can be used as a tool for the study of cancer metastases. A novel design of microfluidic chip used for enrichment of circulating tumor cells is presented in this paper. An integration of DLD method and negative enrichment method were designed to improve the throughput and recovery rate while getting intact CTCs. The DLD stage is used to separate CTCs from blood cells preliminarily, and the negative enrichment stage is used to acquire purified CTCs. Both of them were simulated with COMSOL Multiphysics. Simulation results showed that triangular micro-posts have better performance in DLD stage, and wave structures could generate better disturbance effect than herringbone structures. This chip provides a potential approach with high throughput and purity for the enrichment of CTCs.

scholarly journals Fate and characterization of circulating tumor cells in a NOD/SCID mouse model of human hepatocellular carcinoma

Oncogene ◽  
2006 ◽  
Vol 25 (29) ◽  
pp. 4067-4075 ◽  
Author(s):  
O Scatton ◽  
F Chiappini ◽  
P Riou ◽  
A Marconi ◽  
R Saffroy ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Mouse Model ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Scid Mouse ◽  
Human Hepatocellular Carcinoma ◽  
Scid Mouse Model

Identification and Characterization of Circulating Tumor Cells in Men Who have Undergone Prostatectomy for Clinically Localized, High Risk Prostate Cancer

2019 ◽  
Vol 202 (4) ◽  
pp. 732-741 ◽  
Author(s):  
Terence W. Friedlander ◽  
Christopher Welty ◽  
Archana Anantharaman ◽  
Joseph D. Schonhoft ◽  
Adam Jendrisak ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
High Risk ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
High Risk Prostate Cancer ◽  
Risk Prostate Cancer ◽  
Identification And Characterization
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