Abstract 5804: A novel copper(II) complex of tolfenamic acid exhibits anticancer activity in pancreatic cancer cells via downregulation of transcription factors Sp1 and Sp3 and an anti-apoptotic protein, survivin

Mapping Intimacies ◽

10.1158/1538-7445.am2018-5804 ◽

2018 ◽

Author(s):

Myrna L. Hurtado ◽

Umesh T. Sankpal ◽

Shahela Mahammad ◽

Jaya Chhabra ◽

Deondra K. Brown ◽

...

Keyword(s):

Pancreatic Cancer ◽

Transcription Factors ◽

Anticancer Activity ◽

Cancer Cells ◽

Tolfenamic Acid ◽

Pancreatic Cancer Cells ◽

Apoptotic Protein

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Polyphenol-rich extract of Salvia chinensis exhibits anticancer activity in different cancer cell lines, and induces cell cycle arrest at the G0/G1-phase, apoptosis and loss of mitochondrial membrane potential in pancreatic cancer cells

Molecular Medicine Reports ◽

10.3892/mmr.2015.4074 ◽

2015 ◽

Vol 12 (4) ◽

pp. 4843-4850 ◽

Cited By ~ 8

Author(s):

QUAN ZHAO ◽

XUE-CHEN HUO ◽

FU-DONG SUN ◽

RUI-QIAN DONG

Keyword(s):

Cell Cycle ◽

Pancreatic Cancer ◽

Membrane Potential ◽

Anticancer Activity ◽

Cell Cycle Arrest ◽

Cancer Cells ◽

Mitochondrial Membrane ◽

G1 Phase ◽

Cycle Arrest ◽

Pancreatic Cancer Cells

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Next generation sequencing and functional pathway analysis to understand the mechanism of action of copper-tolfenamic acid against pancreatic cancer cells

Process Biochemistry ◽

10.1016/j.procbio.2019.10.022 ◽

2020 ◽

Vol 89 ◽

pp. 155-164

Author(s):

Myrna Hurtado ◽

Laszlo Prokai ◽

Umesh T. Sankpal ◽

Blair Levesque ◽

Rajasekhar Maram ◽

...

Keyword(s):

Pancreatic Cancer ◽

Next Generation Sequencing ◽

Cancer Cells ◽

Pathway Analysis ◽

Mechanism Of Action ◽

Tolfenamic Acid ◽

Next Generation ◽

Pancreatic Cancer Cells ◽

Functional Pathway ◽

Generation Sequencing

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Abstract 4811: Functional pathway analysis in pancreatic cancer cells treated with a novel anti-cancer agent, copper-tolfenamic acid

10.1158/1538-7445.am2019-4811 ◽

2019 ◽

Author(s):

Myrna Hurtado ◽

Laszlo Prokai ◽

Umesh T. Sankpal ◽

Blair Levesque ◽

Rajasekhar Maram ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Pathway Analysis ◽

Tolfenamic Acid ◽

Pancreatic Cancer Cells ◽

Anti Cancer ◽

Cancer Agent ◽

Functional Pathway

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4-methylumbelliferone, a hyaluronan synthase suppressor, enhances the anticancer activity of gemcitabine in human pancreatic cancer cells

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-005-0016-5 ◽

2005 ◽

Vol 57 (2) ◽

pp. 165-170 ◽

Cited By ~ 63

Author(s):

Hideaki Nakazawa ◽

Shuichi Yoshihara ◽

Daisuke Kudo ◽

Hajime Morohashi ◽

Ikuko Kakizaki ◽

...

Keyword(s):

Pancreatic Cancer ◽

Anticancer Activity ◽

Cancer Cells ◽

Human Pancreatic Cancer ◽

Hyaluronan Synthase ◽

Pancreatic Cancer Cells

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Concomitant Targeting of Multiple Key Transcription Factors Effectively Disrupts Cancer Stem Cells Enriched in Side Population of Human Pancreatic Cancer Cells

PLoS ONE ◽

10.1371/journal.pone.0073942 ◽

2013 ◽

Vol 8 (9) ◽

pp. e73942 ◽

Cited By ~ 21

Author(s):

Xiyan Wang ◽

Quentin Liu ◽

Benxin Hou ◽

Wei Zhang ◽

Min Yan ◽

...

Keyword(s):

Pancreatic Cancer ◽

Stem Cells ◽

Transcription Factors ◽

Cancer Stem Cells ◽

Cancer Cells ◽

Side Population ◽

Human Pancreatic Cancer ◽

Pancreatic Cancer Cells

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Abstract 2063: Synergistic anticancer activity of Sorafenib in combination with HS-173, a novel PI3K inhibitor against pancreatic cancer cells.

10.1158/1538-7445.am2013-2063 ◽

2013 ◽

Author(s):

Sun-Mi Yun ◽

Kyung Hee Jung ◽

Hyunseung Lee ◽

Byung Hee Park ◽

Hong Hua Yan ◽

...

Keyword(s):

Pancreatic Cancer ◽

Anticancer Activity ◽

Cancer Cells ◽

Pi3k Inhibitor ◽

Pancreatic Cancer Cells

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Expression of Concern: Concomitant Targeting of Multiple Key Transcription Factors Effectively Disrupts Cancer Stem Cells Enriched in Side Population of Human Pancreatic Cancer Cells

PLoS ONE ◽

10.1371/journal.pone.0174194 ◽

2017 ◽

Vol 12 (3) ◽

pp. e0174194

Author(s):

Keyword(s):

Pancreatic Cancer ◽

Stem Cells ◽

Transcription Factors ◽

Cancer Stem Cells ◽

Cancer Cells ◽

Side Population ◽

Human Pancreatic Cancer ◽

Pancreatic Cancer Cells

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Regulatory Effects of X-linked Inhibitor of Apoptosis Protein and Pro-apoptotic Protein Smac on Apoptosis Resistance to Chemotherapy in Pancreatic Cancer Cells

The Chinese-German Journal of Clinical Oncology ◽

10.1007/s10330-005-0377-6 ◽

2006 ◽

Vol 5 (1) ◽

pp. 31-35

Author(s):

Jihui DU ◽

Houde ZHANG ◽

Ping LEI ◽

Zhuowa SU ◽

Fang ZHENG ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Inhibitor Of Apoptosis ◽

Apoptosis Resistance ◽

Inhibitor Of Apoptosis Protein ◽

Pancreatic Cancer Cells ◽

Apoptotic Protein ◽

Apoptosis Protein ◽

Regulatory Effects ◽

Resistance To Chemotherapy

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COMPREHENSIVE ANALYSIS OF THE SP/KLF FAMILY OF TRANSCRIPTION FACTORS IN THE TGF-BETA SIGNALING IN PANCREATIC CANCER CELLS

Pancreas ◽

10.1097/01.mpa.0000193781.42217.51 ◽

2005 ◽

Vol 31 (4) ◽

pp. 474

Author(s):

M J Truty ◽

M E Fernandez-Zapico ◽

R Urrutia

Keyword(s):

Pancreatic Cancer ◽

Transcription Factors ◽

Cancer Cells ◽

Comprehensive Analysis ◽

Tgf Beta ◽

Pancreatic Cancer Cells

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Polyphenol‑rich extract of Saliva chinensis exhibits anticancer activity in different cancer cell lines, and induces cell cycle arrest at the G0/G1‑phase, apoptosis and loss of mitochondrial membrane potential in pancreatic cancer cells

Molecular Medicine Reports ◽

10.3892/mmr.2021.12101 ◽

2021 ◽

Vol 23 (6) ◽

Author(s):

Quan Zhao ◽

Xue-Chen Huo ◽

Fu-Dong Sun ◽

Rui-Qian Dong

Keyword(s):

Cell Cycle ◽

Pancreatic Cancer ◽

Membrane Potential ◽

Anticancer Activity ◽

Cell Cycle Arrest ◽

Cancer Cells ◽

Mitochondrial Membrane ◽

G1 Phase ◽

Cycle Arrest ◽

Pancreatic Cancer Cells

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