Abstract 1395: Humanized GD2 antibody for targeted radiopharmaceutical therapy of human and canine osteosarcoma

2021 ◽  
Author(s):  
Yingli Fu ◽  
Jing Yu ◽  
Ioanna Liatsou ◽  
Anders Josefsson ◽  
Yong Du ◽  
...  
Keyword(s):  
Canine Osteosarcoma ◽  
Radiopharmaceutical Therapy

Canine osteosarcoma checkpoint expression correlates with metastasis and T-cell infiltrate

2021 ◽  
Vol 232 ◽  
pp. 110169
Author(s):  
Matthew J. Cascio ◽  
Elizabeth M. Whitley ◽  
Bikash Sahay ◽  
Galaxia Cortes-Hinojosa ◽  
Lung-Ji Chang ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Infiltrate ◽  
Canine Osteosarcoma

miR-1 and miR-133b expression in canine osteosarcoma

2018 ◽  
Vol 117 ◽  
pp. 133-137 ◽  
Author(s):  
Leonardi Leonardo ◽  
Pazzaglia Laura ◽  
Benassi Maria Serena
Keyword(s):  
Canine Osteosarcoma

Maxillectomy and targeted radionuclide therapy with 153Sm-EDTMP in a recurrent canine osteosarcoma

1996 ◽  
Vol 37 (5) ◽  
pp. 241-246 ◽  
Author(s):  
L. Moe ◽  
M. Boysen ◽  
M. Aas ◽  
L. Lønaas ◽  
H. Gamlem ◽  
...  
Keyword(s):  
Radionuclide Therapy ◽  
Targeted Radionuclide Therapy ◽  
Canine Osteosarcoma

Effects of etoposide alone and in combination with piroxicam on canine osteosarcoma cell lines

2016 ◽  
Vol 218 ◽  
pp. 51-59 ◽  
Author(s):  
S.M. Ong ◽  
K. Saeki ◽  
Y. Tanaka ◽  
R. Nishimura ◽  
T. Nakagawa
Keyword(s):  
Cell Lines ◽  
Osteosarcoma Cell ◽  
Canine Osteosarcoma

THE EFFECT OF THE BISPHOSPHONATE ALENDRONATE ON VIABILITY OF CANINE OSTEOSARCOMA CELLS IN VITRO

2004 ◽  
Vol 40 (3) ◽  
pp. 113 ◽  
Author(s):  
JAMES P. FARESE ◽  
JENNA ASHTON ◽  
ROWAN MILNER ◽  
LINDA-LEE AMBROSE ◽  
JAMES VAN GILDER
Keyword(s):  
Osteosarcoma Cells ◽  
Canine Osteosarcoma

scholarly journals Recent Advances in the Discovery of Biomarkers for Canine Osteosarcoma

2021 ◽  
Vol 8 ◽  
Author(s):  
Anita K. Luu ◽  
Geoffrey A. Wood ◽  
Alicia M. Viloria-Petit
Keyword(s):  
Clinical Practice ◽  
Standard Treatment ◽  
Predictive Biomarkers ◽  
Response To Treatment ◽  
Liquid Biopsies ◽  
Future Directions ◽  
Diagnostic Biomarkers ◽  
Canine Osteosarcoma ◽  
The Past ◽  
Biomarker Research

Canine osteosarcoma (OSA) is an aggressive malignancy that frequently metastasizes to the lung and bone. Not only has there been essentially no improvement in therapeutic outcome over the past 3 decades, but there is also a lack of reliable biomarkers in clinical practice. This makes it difficult to discriminate which patients will most benefit from the standard treatment of amputation and adjuvant chemotherapy. The development of reliable diagnostic biomarkers could aid in the clinical diagnosis of primary OSA and metastasis; while prognostic, and predictive biomarkers could allow clinicians to stratify patients to predict response to treatment and outcome. This review summarizes biomarkers that have been explored in canine OSA to date. The focus is on molecular biomarkers identified in tumor samples as well as emerging biomarkers that have been identified in blood-based (liquid) biopsies, including circulating tumor cells, microRNAs, and extracellular vesicles. Lastly, we propose future directions in biomarker research to ensure they can be incorporated into a clinical setting.

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