Abstract GS6-05: The impact of breast cancer surgery on quality of life: Long term results from E5103

Background and aim: Mucositis is a well-known side effect to chemotherapy treatment after breast cancer surgery. The number of women who experience oral complication that is not classified as mucositis is less investigated as well as the impact of oral complication on the women’s quality of life. \textit{Aim:} To describe how many women with breast cancer report oral complications during their adjuvant chemotherapy with Ebirubicin, Cyclophosphamide and Taxotere or Taxol, to describe which oral complications the women report and the impact the oral complication has on women’s daily life and quality of life.Methods: A cross-sectional design was used. The women were invited to fill out a self-composed questionnaire at proximal 12 weeks after initiation of the treatment. The questionnaire had two scales to summarize information about oral complication and their impact on daily living was used. The questionnaire has been face- and content validated. Internal consistency was between 0.76 to 0.83.Results: All 101 women had experienced oral complications to some extent. A linear regression analysis has reviled that redness, coaching and changes of taste explained 74% of reported reduction in quality of life. There was a positive correlation between the sum of symptoms (number of symptoms and duration) and reported quality of life score r = .480 (p = .000).Conclusions: Oral complications was experienced by all women who were treated with CT after breast cancer surgery. Redness, coaching and changes of taste were significant contributors to reducing quality of life and need to be prevented during chemotherapy.

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Self-perceived, but not objective lymphoedema is associated with decreased long-term health-related quality of life after breast cancer surgery

European Journal of Surgical Oncology ◽

10.1016/j.ejso.2014.12.006 ◽

2015 ◽

Vol 41 (4) ◽

pp. 577-584 ◽

Cited By ~ 23

Author(s):

H. Sackey ◽

H. Johansson ◽

K. Sandelin ◽

Göran Liljegren ◽

G. MacLean ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Surgery ◽

Breast Cancer Surgery ◽

Health Related Quality ◽

Related Quality ◽

Health Related

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Effects of early rehabilitation treatment on the functional recovery and quality of life in patients three months after breast cancer surgery

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh190521079t ◽

2020 ◽

Vol 148 (1-2) ◽

pp. 81-86

Author(s):

Sanja Tomic ◽

Goran Malenkovic ◽

Nensi Lalic ◽

Marko Bojovic ◽

Tomic Slobodan

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Functional Recovery ◽

Shoulder Joint ◽

Positive Impact ◽

Cancer Surgery ◽

Breast Cancer Surgery ◽

Sf 36 ◽

The Impact

Introduction/Objective. Breast cancer surgery is associated with the risk of developing functional constraints that may negatively affect the quality of patients? lives. The objective of the study was to determine the impact of early postoperative exercises three months after surgery on functional recovery and the quality of life of patients who were operated on. Methods. A group of 149 patients was tested, divided by the type of surgery into two groups. The assessment of the quality of life by the SF-36 questionnaire and functional testing were done three months after surgery; the extent of movement in the shoulder joint and of the limbs was measured as well. Results. On basic measurements of the quality of life, the average results of SF-36 showed the highest values in the domain of physical functioning, while the lowest value was in the vitality and energy domain. After the realized rehabilitation activities, the results of the SF-36 questionnaire indicated the increase in all domains and components at the significance level of p = 0.001, except for the general health domain (p = 0.04). Preoperatively, a moderate negative association of mobility and the SF-36 questionnaire component with the overall health parameter was determined, whereby the lower value of the SF-36 questionnaire was followed by a larger deviation in the flexion movements and abduction of the shoulder joint. Conclusion. The results of our study support the concept of early-initiated rehabilitation interventions and confirm the positive impact on the quality of life of patients operated on for breast cancer in the three-month follow-up period.

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Changes in arm morbidities and health-related quality of life after breast cancer surgery - a five-year follow-up study

Acta Oncologica ◽

10.1080/02841860903061691 ◽

2009 ◽

pp. 1-8

Author(s):

Åse Sagen ◽

Rolf Kåresen ◽

Leiv Sandvik ◽

May Arna Risberg

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Surgery ◽

Breast Cancer Surgery ◽

Health Related Quality ◽

Follow Up Study ◽

Related Quality ◽

Health Related

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The impact of lymphedema on health-related quality of life up to 10 years after breast cancer treatment

npj Breast Cancer ◽

10.1038/s41523-021-00276-y ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Mads G. Jørgensen ◽

Navid M. Toyserkani ◽

Frederik G. Hansen ◽

Anette Bygum ◽

Jens A. Sørensen

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Treatment ◽

Breast Cancer Treatment ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

The Impact

AbstractThe impact of breast cancer-related lymphedema (BCRL) on long-term quality of life is unknown. The aim of this study was to investigate the impact of BCRL on health-related quality of life (HRQoL) up to 10 years after breast cancer treatment. This regional population-based study enrolled patients treated for breast cancer with axillary lymph node dissection between January 1st 2007 and December 31th 2017. Follow up and assessments of the included patients were conducted between January 2019 and May 2020. The study outcome was HRQoL, evaluated with the Lymphedema Functioning, Disability and Health Questionnaire, the Disabilities of the Arm, Shoulder and Hand Questionnaire and the Short Form (36) Health Survey Questionnaire. Multivariate linear logistic regression models adjusted for confounders provided mean score differences (MDs) with 95% confidence intervals in each HRQoL scale and item. This study enrolled 244 patients with BCRL and 823 patients without BCRL. Patients with BCRL had significantly poorer HRQoL than patients without BCRL in 16 out of 18 HRQoL subscales, for example, in physical function (MDs 27, 95%CI: 24; 30), mental health (MDs 24, 95%CI: 21; 27) and social role functioning (MDs 20, 95%CI: 17; 23). Age, BMI, BCRL severity, hand and dominant arm affection had only minor impact on HRQoL (MDs < 5), suggesting a high degree of inter-individual variation in coping with lymphedema. This study showed that BCRL is associated with long-term impairments in HRQoL, especially affecting the physical and psychosocial domains. Surprisingly, BCRL diagnosis rather than clinical severity drove the largest impairments in HRQoL.

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Effect of Rapid Rehabilitation Concepts on Quality of Life and Pain in Patients Undergoing Radical Breast Cancer Surgery in Perioperative Period

Tobacco Regulatory Science ◽

10.18001/trs.7.5.74 ◽

2021 ◽

Vol 7 (5) ◽

pp. 1538-1544

Author(s):

Xin Li ◽

Hai-yan An ◽

Yi Zhao ◽

Mingli Ji ◽

Jing An ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Perioperative Period ◽

Nursing Intervention ◽

Cancer Surgery ◽

Breast Cancer Surgery ◽

Control Group ◽

T Lymphocyte Subsets ◽

Significant Difference

To study the effect of rapid rehabilitation nursing on patients’ quality of life and pain level during the perioperative period of radical breast cancer surgery. Methods: 126 patients who were hospitalized in our hospital from January 2018 to February 2020 and underwent radical breast cancer surgery were divided into control group and rapid rehabilitation group according to the perioperative period intervention method. Routine nursing intervention and rapid rehabilitation nursing intervention were used respectively. The general conditions of the two groups were recorded, and the differences of T cell subsets before operation and 3 days after operation were detected. Visual analogue pain (VAS) score was used to evaluate the changes of pain degree at 1 day, 3 days and 5 days after operation and on the day of discharge. Postoperative complications and satisfaction were compared between the two groups. Quality of life (QOL) was assessed at 1 month and 3 months after operation using the CARES-SF score. Results: Anesthesia waking time (26.12 ± 5.77) min, off-bed activity time (14.25 ± 2.87) h and hospital stay (7.82 ± 2.15) d in the rapid rehabilitation group were shorter than those in the control group (P < 0.05). The operation time (92.02 ± 14.78) min and intraoperative blood loss (57.96 ± 13.96) mL in the rapid rehabilitation group were not significantly different from those in the control group (P > 0.05). In the control group, 3d after operation, T lymphocyte subsets were decreased gradually than that before operation (P < 0.05), CD3+ was decreased 3d after operation than that before operation in the rapid rehabilitation group (P < 0.05), but CD4+, CD8+, CD4+ / CD8 + 3d after operation had no significant difference than that before operation (P > 0.05). In rapid rehabilitation group, T lymphocyte subsets at 3d after operation were higher than those in the control group (P < 0.05). The postoperative complication rate of the rapid rehabilitation group was lower than that of the control group, and the satisfaction degree was higher than that of the control group, with significant difference (P < 0.05). After follow-up, it was found that the scores of qualities of life, such as physiology, psychosocial, marriage, sexual life and relationship with medical staff in the rapid rehabilitation group were lower than those in the control group at 1 month and 3 months after operation (P < 0.05). Conclusion: The concept of rapid rehabilitation nursing can stabilize the immune function of patients after radical breast cancer surgery, promote the postoperative rehabilitation and improve the quality of life after operation.

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