Abstract IA15: Biology and clinical implications of circulating tumor cells and bone marrow micrometastasis

Author(s):  
Klaus Pantel
2008 ◽  
Vol 43 (12) ◽  
pp. 2182-2185 ◽  
Author(s):  
Tatsuo Kuroda ◽  
Nobuyuki Morikawa ◽  
Kentaro Matsuoka ◽  
Akihiro Fujino ◽  
Toshiro Honna ◽  
...  

2008 ◽  
Vol 14 (16) ◽  
pp. 5013-5021 ◽  
Author(s):  
Catherine Alix-Panabières ◽  
Sabine Riethdorf ◽  
Klaus Pantel

2014 ◽  
Vol 7 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Simon A Joosse ◽  
Tobias M Gorges ◽  
Klaus Pantel

2010 ◽  
Vol 2010 ◽  
pp. 1-9 ◽  
Author(s):  
Georg Lurje ◽  
Marc Schiesser ◽  
Andreas Claudius Hoffmann ◽  
Paul Magnus Schneider

Since their introduction more than 50 years by Engell, circulating tumor cells (CTCs) have been evaluated in cancer patients and their detection has been correlated with clinical outcome, in esophageal, gastric, and colorectal cancer. With the availability of refined technologies, the identification of CTCs from peripheral blood is emerging as a useful tool for the detection of malignancy, monitoring disease progression, and measuring response to therapy. However, increasing evidence suggests a variety of factors to be responsible for disease progression. The analysis of a single CTC marker is therefore unlikely to accurately predict progression of disease with sufficient resolution and reproducibility. Here we discuss the current concept of CTCs, summarize the available techniques for their detection and characterization, and aim to provide a comprehensive update on the clinical implications of CTCs in gastrointestinal (GI) malignancies.


2019 ◽  
Vol 24 (9) ◽  
Author(s):  
Emne A. Abdallah ◽  
Alexcia C. Braun ◽  
Bianca C.T.C.P. Flores ◽  
Laís Senda ◽  
Ana Cláudia Urvanegia ◽  
...  

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