scholarly journals Combined Genetic Biomarkers and Betel Quid Chewing for Identifying High-Risk Group for Oral Cancer Occurrence

2017 ◽  
Vol 10 (6) ◽  
pp. 355-362 ◽  
Author(s):  
Chia-Min Chung ◽  
Chien-Hung Lee ◽  
Mu-Kuan Chen ◽  
Ka-Wo Lee ◽  
Cheng-Che E. Lan ◽  
...  
Keyword(s):  
High Risk ◽  
Oral Cancer ◽  
Risk Group ◽  
High Risk Group ◽  
Betel Quid ◽  
Genetic Biomarkers ◽  
Cancer Occurrence ◽  
Betel Quid Chewing

Mouth self-examination as a screening tool for oral cancer in a high-risk group of patients with Fanconi anemia

2014 ◽  
Vol 118 (4) ◽  
pp. 440-446 ◽  
Author(s):  
Camila Pinheiro Furquim ◽  
Allana Pivovar ◽  
Laura Grein Cavalcanti ◽  
Renata Fuentes Araújo ◽  
Carmem Maria Sales Bonfim ◽  
...  
Keyword(s):  
High Risk ◽  
Oral Cancer ◽  
Fanconi Anemia ◽  
Screening Tool ◽  
Risk Group ◽  
High Risk Group ◽  
Self Examination

scholarly journals Oral Cancer Awareness And Practice Of Risk Habits And Mouth Self-Examination In High Risk Indigenous Community In Sarawak, Malaysia

2017 ◽  
Vol 16 (2) ◽  
Author(s):  
Thaddius Herman Maling ◽  
Jennifer Geraldine Doss ◽  
Low Wah Yun
Keyword(s):  
High Risk ◽  
Oral Cancer ◽  
Low Income ◽  
Education Level ◽  
Indigenous Community ◽  
Betel Quid ◽  
Cancer Awareness ◽  
Cross Sectional Survey ◽  
Betel Quid Chewing ◽  
Self Examination

Introduction: This study was to obtain baseline information and its associated factors on oral cancer awareness, practice of risk habits and mouth self-examination (MSE) among selected highrisk indigenous community in Sarawak. Materials and Methods: Cross-sectional survey using faceto-face interview was conducted on consented Malaysian, aged ≥15 years old who attended a one day Ministry of Health annual oral cancer screening programme at Bisaya villages in Limbang, Sarawak. Data were analysed using chi-square and multiple logistic regression. Significance level was set at p<0.05. Results:  75.1% of respondents were aware of oral cancer. Smoking was the most recognised risk habits (85.1%). About three-quarter of respondents recognised non-healing ulcer (74.7%) and red/white spot (72.1%) in the mouth as possible early cancer signs. Men had higher prevalence of smoking (85.7%) and drinking (70.8%)(p<0.01), whereas, women had higher percentage of betel quid chewing (62.5%). Low income was significantly associated with smoking and alcohol habits, whereas older age group and lower education level were significantly associated with betel quid chewing. Although 94.8% of respondents agreed that early detection may improve treatment outcome, only 33.8% had heard about MSE. Respondents who ever heard of MSE were 57 times more likely to practice MSE. Conclusion(s):  Majority of selected high-risk indigenous community were aware of oral cancer, however awareness of MSE are still lacking. Gender, age, education level and income were significantly associated with health-risk behaviours. Future health promotion agenda should focus in addressing socio-environment gaps, and develop health education intervention based on specific health behaviour theory.

scholarly journals The Impact of in Intervention Program on Oral Cancer Awareness and Practice of Preventive Behaviors in High-Risk Indigenous Community in Sarawak, Malaysia

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 10s-10s ◽  
Author(s):  
T.H. Maling ◽  
J.G. Doss ◽  
W.Y. Low
Keyword(s):  
High Risk ◽  
Oral Cancer ◽  
Cancer Education ◽  
Intervention Group ◽  
Indigenous Community ◽  
Betel Quid ◽  
Control Group ◽  
Cancer Awareness ◽  
Betel Quid Chewing ◽  
The Impact

Background: Oral cancer is highly prevalent among indigenous people in Sarawak as this population lacks awareness and is known to practice high-risk habits. Aim: This study aimed to develop and evaluate the impact of an educational intervention to improve oral cancer awareness and practice of preventive behavior among high-risk indigenous communities in Sarawak, Malaysia. Methods: A quasi-experimental study was undertaken involving adults in a Bisaya community (with high risk habits) in Limbang, Sarawak. The intervention group received a structured, Health Beliefs Model (HBM) theory-based oral cancer education module, while the control group was exposed to the conventional oral cancer education method during Ministry of Health's community oral cancer and precancer screening program. Face-to-face interviews using a validated structured questionnaire were conducted to obtain baseline information prior to intervention and after one and three months. Descriptive and multivariate statistics were used for analyzing the data using SPSS software. Results: The overall response rate was 99.5%. The final sample comprised of 204 respondents (89 in the control group and 115 in the intervention group). At baseline, 75.1% of respondents had heard about oral cancer, however their in-depth knowledge on risk factors, signs and symptoms and prevention were lacking. The control group had better awareness than the intervention group. Smoking and alcohol drinking were more prevalent in the intervention group, whereas betel quid chewing and practice of mouth self-examination (MSE) were more evident in the control group. At 1-month and 3-month follow-up, there were significantly higher mean scores in all aspects of oral cancer awareness among respondents in the intervention group and these improved levels of awareness were maintained over a period of 1- and 3-months. There were higher proportion of smokers, alcohol drinkers and betel quid chewers in the intervention group who reported quitting their habits or reducing the number of cigarettes smoked per day, frequency of alcohol drinking and betel quid chewing than the control group. The respondents in the intervention group also had significant increase in uptake of MSE and higher proportions who performed it once a month. Conclusion: The structured HBM-based oral cancer health education intervention was shown to have significant impacts on oral cancer knowledge and awareness, cessation and reduction of risk habits and increased the uptake of MSE among respondents in the intervention group of this indigenous community. Therefore, the introduced structured health education intervention is recommended for other communities in Malaysia that practice the same oral cancer risk habits. Considering this indigenous community is of lower socioeconomic status (SES), the introduced intervention could also be extended to other lower SES groups in Malaysia.

Acromegaly and Obstructive Sleep Apnea: Identifying the High-Risk Group

2019 ◽  
Author(s):  
Xiaojun Zhan ◽  
Chandala Chitguppi ◽  
Ethan Berman ◽  
Gurston Nyquist ◽  
Tomas Garzon-Muvdi ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
High Risk ◽  
Risk Group ◽  
High Risk Group ◽  
Obstructive Sleep

Anamnestic factors that shape reproductive health of women with repeated unsuccessful popygamy in vitro fertilization

2016 ◽  
pp. 140-143
Author(s):  
N.V. Cotsabin ◽  
◽  
O.M. Makarchuk ◽  
Keyword(s):  
High Risk ◽  
Risk Group ◽  
Polycystic Ovary ◽  
High Risk Group ◽  
Stress Factors ◽  
Control Group ◽  
Fertilization In Vitro ◽  
Infertile Women ◽  
Group I

The proportion of patients with multiple unsuccessful attempts of assisted reproductive technology (ART) is about 30% of all patients treated with the use of ART. Women with history of unsuccessful ART attempts - a special category of patients who require emergency attention and a thorough examination at the stage of preparation for superovulation stimulation,the selection of embryos and endometrium preparation for embryo transfer. The objective: to distinguish high-risk group of unsuccessful attempts based on a detailed analysis of anamnestic and clinical data of infertile women with repeated unsuccessful ART attempts that requires more in-depth study of hormonal features, ovarian reserve and condition of the endometrium. Materials and methods. For better understanding of the problem of repeated unsuccessful ART attempts and сreation of efficient infertility treatment algorithms for these couples we conducted a thorough analysis of anamnestic data of three groups of infertile women (105 patients), which were distributed by age: group I – younger than 35, the II group – from 35 to 40, the III group - over 40 years. These groups of patients were compared with each other and with the control group of healthy women (30 persons). Results. Leading stress factors in the percentage three times prevailed in the group of infertile women and had a direct connection with the fact of procedure «fertilization in vitro» and chronic stressors caused by prolonged infertility. Primary infertility was observed significantly more frequent in patients younger than 35 years (p <0.05), secondary infertility - mostly in the second and third experimental groups (p <0.05). Noteworthy significant percentage of wellknown causes of infertility and idiopathic factor in all groups, and the prevalence of tubal-peritoneal factor in the second and third experimental groups, and endocrine dysfunction in the I experimental group. The most common disorder among this category of woman was polycystic ovary syndrome. Frequency of usual miscarriage among patients of I ana II groups was two times higher than in the third group (p <0.05). Among the experimental groups the leading place belongs urinary tract infection, respiratory tract diseases, pathologies of the cardiovascular system. Data of the stratified analysis show an increase likelihood of repeated unsuccessful ART attempts under the influence of constant chronic stress (odds ratio OR=2.06; 95% CI: 0.95–3.17; p<0.05). Conclusions. Among infertile patients with repeated unsuccessful ART attempts must be separated a high risk group of failures. The identity depends on the duration of infertility, female age and leading combination of factors. Key words: repeated unsuccessful ART attempts, anamnesis, infertility, high risk.

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