Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Anti-Tumor T-cell Immunity

Cancer Discovery ◽

10.1158/2159-8290.cd-20-0873 ◽

2020 ◽

pp. CD-20-0873

Author(s):

Aayoung Hong ◽

Marco Piva ◽

Sixue Liu ◽

Willy Hugo ◽

Shirley H. Lomeli ◽

...

Keyword(s):

T Cell ◽

Mek Inhibitor ◽

T Cell Immunity ◽

Cell Immunity ◽

Inhibitor Resistance ◽

Durable Suppression

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The diverse functions of transcription factors in T cell immunity during LCMV infection

Zeitschrift für Gastroenterologie ◽

10.1055/s-0035-1568116 ◽

2015 ◽

Vol 53 (12) ◽

Author(s):

MD Grusdat ◽

PA Lang

Keyword(s):

Transcription Factors ◽

T Cell ◽

T Cell Immunity ◽

Cell Immunity ◽

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Assessment of tumor antigen specific T cell immunity and cytokine milieu at diagnosis in patients with high risk Hodgkin Lymphoma treated on Children’s Oncology Group trial AHOD1331

10.1055/s-0040-1701840 ◽

2020 ◽

Author(s):

H Dave ◽

T M Horton ◽

M Mai ◽

D Saunders ◽

G Jenkins ◽

...

Keyword(s):

T Cell ◽

High Risk ◽

Hodgkin Lymphoma ◽

Tumor Antigen ◽

T Cell Immunity ◽

Oncology Group ◽

Cell Immunity ◽

Cytokine Milieu ◽

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IL-7 and IL-15: Biology and Roles in T-Cell Immunity in Health and Disease

Critical Reviews™ in Immunology ◽

10.1615/critrevimmunol.v28.i4.40 ◽

2008 ◽

Vol 28 (4) ◽

pp. 325-339 ◽

Author(s):

Hang-Rae Kim ◽

Kyung-A Hwang ◽

Sung-Hwan Park ◽

Insoo Kang

Keyword(s):

T Cell ◽

T Cell Immunity ◽

Cell Immunity ◽

Health And Disease

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Faculty Opinions recommendation of Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004150.10004 ◽

2001 ◽

Author(s):

JoAnne Flynn

Keyword(s):

T Cell ◽

Differential Regulation ◽

T Cell Immunity ◽

T Cell Memory ◽

Cell Memory ◽

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Faculty Opinions recommendation of Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717952761.793458241 ◽

2012 ◽

Author(s):

Tania Watts ◽

Derek Clouthier ◽

Achire Mbanwi

Keyword(s):

T Cell ◽

Natural Killer Cell ◽

Natural Killer ◽

Chronic Infection ◽

Cell Activation ◽

Killer Cell ◽

T Cell Immunity ◽

Cell Immunity ◽

Immune Pathology

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Faculty Opinions recommendation of Multiple antigen-presenting system (MAPS) to induce comprehensive B- and T-cell immunity.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718049917.793491175 ◽

2014 ◽

Author(s):

David Pompliano

Keyword(s):

T Cell ◽

T Cell Immunity ◽

Cell Immunity ◽

Multiple Antigen ◽

System Maps ◽

Antigen Presenting

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Faculty Opinions recommendation of Seasonal FluMist vaccination induces cross-reactive T cell immunity against H1N1 (2009) influenza and secondary bacterial infections.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718384266.793495075 ◽

2014 ◽

Author(s):

Albert Osterhaus

Keyword(s):

T Cell ◽

Bacterial Infections ◽

T Cell Immunity ◽

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Faculty Opinions recommendation of T cell immunity. Functional heterogeneity of human memory CD4⁺ T cell clones primed by pathogens or vaccines.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725264608.793503628 ◽

2015 ◽

Author(s):

Scott L Butler

Keyword(s):

T Cell ◽

Human Memory ◽

T Cell Immunity ◽

Functional Heterogeneity ◽

T Cell Clones ◽

Cell Immunity ◽

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Faculty Opinions recommendation of A Two-Component DNA-Prime/Protein-Boost Vaccination Strategy for Eliciting Long-Term, Protective T Cell Immunity against Trypanosoma cruzi.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725478174.793506990 ◽

2015 ◽

Author(s):

Herbert Tanowitz ◽

Fabiana Machado

Keyword(s):

T Cell ◽

Trypanosoma Cruzi ◽

Vaccination Strategy ◽

T Cell Immunity ◽

Boost Vaccination ◽

Cell Immunity ◽

Protein Boost ◽

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Faculty Opinions recommendation of Critical role for CD103(+)/CD141(+) dendritic cells bearing CCR7 for tumor antigen trafficking and priming of T cell immunity in melanoma.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726542716.793524820 ◽

2016 ◽

Author(s):

Joyce Solheim

Keyword(s):

Dendritic Cells ◽

T Cell ◽

Tumor Antigen ◽

Critical Role ◽

T Cell Immunity ◽

Cell Immunity ◽

Antigen Trafficking

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