The Biomed II IPTRP Project: Implementation of Diagnostic Instruments

2002 ◽  
Vol 8 (4) ◽  
pp. 201-203 ◽  
Author(s):  
Eric Broekaert ◽  
Marie-Jeanne Haack ◽  
Charles Kaplan ◽  
David Oberg ◽  
Björn Sallmén ◽  
...  
Keyword(s):  
Project Implementation ◽  
Diagnostic Instruments

Calibration of a Lyophilized Pooled Plasma as Candidate Reference Plasma for Standardization of the Prothrombin Time Ratio

1993 ◽  
Vol 13 (02) ◽  
pp. 96-105 ◽  
Author(s):  
H. Beeser ◽  
U. Becker ◽  
H. J. Kolde ◽  
E. Spanuth ◽  
P. Witt ◽  
...  
Keyword(s):  
Prothrombin Time ◽  
International Study ◽  
International Normalized Ratio ◽  
Measurement Methods ◽  
Factor V ◽  
Diagnostic Instruments ◽  
Plasma Pool ◽  
Normal Plasma ◽  
German Association ◽  
Prothrombin Time Ratio

SummaryThe prothrombin time (PT), obtained from a fresh normal plasma pool (FPP), is the basis both for the establishment of the 100% activity (normal plasma) and for the ratio calculation used in the International Normalized Ratio (INR) according to the recommendations of the ICSH/ICTH (6). Today the PT of lyophilized normal plasma pools are successfully used as reference for the assessment of samples in proficiency studies. However, a lack of comparability is to be recognized. Therefore the Committee of Hematology of the German Association of Diagnostics’ and Diagnostic Instruments’ Manufacturers (VDGH) decided to produce a candidate reference plasma (VDGH Reference Plasma) which was calibrated against fresh normal plasma pools in an international study.The basic calibration was performed by using the same certified BCR thromboplastin (BCT/099) by all participants. The endpoint was determined manually and by using the coagulometer Schnitger-Gross. In additional testings each participant used his own routine thromboplastins and methods. Calculating the ratio [PT VDGH Reference Plasma (sec)/PT fresh normal plasma pool (sec)] the VDGH Reference Plasma showed a deviation from the average fresh normal plasma pool of 1.05 both with the BCT/099 and with all thromboplastins. There were obtained some statistical differences between “plain” and “combined’’ (added factor V and fibrinogen) thromboplastins. No statistical difference was found between the different endpoint measurement methods (manual, mechanical, optical).In spite of these statistical deviations the VDGH Reference Plasma can be used for the standardization of the PT-normal (100%) value with different ratios for plain (1.06) and combined (1.02) thromboplastins. The manufacturers will use this VDGH Reference Plasma for the calibration of their commercially available calibration plasmas, which allows the user of such a material to calculate a calibrated 100% PT value.

Designing Risk Qualitative Assessment on Fiber Optic Instalation Project in Indonesia

2018 ◽  
Vol 2 (01) ◽  
Author(s):  
Devi Pratami
Keyword(s):  
Risk Assessment ◽  
Risk Analysis ◽  
Fiber Optic ◽  
Qualitative Assessment ◽  
Quality And Safety ◽  
Project Implementation ◽  
Cost Impact ◽  
Implementation Assessment ◽  
The Impact ◽  
Impact Cost

A project always has risks that can lead to project failure. In the project, a risk analysis is required to provide an evaluation for the project to proceed as planned. In the event of inadequate planning and ineffective control, it will result in irregularities identified as a risk to the project. This study aims to analyze the qualitative risk on Fiber Optic Installaion project in Sukabumi, West Java, Indonesia. In addition, risk assessment is undertaken on project implementation. Assessment of risk using the impact and probability to measure the impact of risk occurrence. The impacts are more detailed by classified by time impact, cost impact, quality impact, safety and security impact, proximity. The result is there are 36 risk that may occur and mostly risks are associaated by quality and safety&security impact.

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