Direct Immunofluorescence in Recurrent Aphthous Ulcers and Behçet’s Disease

Dermatology ◽  
1983 ◽  
Vol 167 (6) ◽  
pp. 293-298 ◽  
Author(s):  
G. Reimer ◽  
L. Luckner ◽  
O.P. Hornstein
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Direct Immunofluorescence ◽  
Behcet's Disease ◽  
Aphthous Ulcers ◽  
Recurrent Aphthous Ulcers

scholarly journals Bilateral Neuroretinitis and a Unilateral Superior Hemivein Occlusion with Frosted Branch Angiitis Pattern Presenting Simultaneously in Behçet's Disease

2016 ◽  
Vol 7 (1) ◽  
pp. 141-147 ◽  
Author(s):  
Roy Schwartz ◽  
Sara Borok ◽  
Michaella Goldstein ◽  
Anat Kesler ◽  
Keren Regev ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Erythema Nodosum ◽  
Behçet's Disease ◽  
Clinical Manifestations ◽  
Unique Case ◽  
Behcet's Disease ◽  
Frosted Branch Angiitis ◽  
Ocular Manifestations ◽  
Aphthous Ulcers

Purpose: To report a unique case of Behçet's disease that presented with atypical ocular manifestations. Methods: Case report. Results: A 23-year-old homosexual male presented with bilateral anterior uveitis, vitritis, neuroretinitis and a unilateral superior hemivein occlusion with frosted branch angiitis pattern. These were accompanied by systemic findings of recurrent oral aphthous ulcers, erythema nodosum, and neurological and gastrointestinal involvement. A positive HLA-B51 examination supported the diagnosis of Behçet's disease. Conclusion: Neuroretinitis and frosted branch angiitis may be the clinical manifestations of Behçet's disease and may present simultaneously.

scholarly journals Clinical Effect of Non-Thermal CO2 Laser Therapy (NTCLT) on Pain Relief of Oral Aphthous Ulcers of Behçet’s Disease

2021 ◽  
Vol 12 (1) ◽  
pp. e72-e72
Author(s):  
Nasrin Zand ◽  
Leila Ataie-Fashtami ◽  
Parvin Mansouri ◽  
Mohsen Fateh ◽  
Afshan Shirkavand
Keyword(s):  
Pain Relief ◽  
Adverse Effects ◽  
Laser Therapy ◽  
Behçet’S Disease ◽  
Co2 Laser ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Behcet's Disease ◽  
Oral Ulcers ◽  
Aphthous Ulcers

Introduction: Behçet’s disease (BD) is a debilitating and chronic vasculitis which can affect multiple organs. Recurrent oral aphthosis is the most common clinical feature of BD. The remarkable pain associated with painful oral ulcers can exert a major impact on the patients’ quality of life. Relieving pain of these oral ulcers is an essential approach in the management of mucocutaneous lesions of BD. Non-thermal CO2 laser therapy (NTCLT) as a novel photobiomodulative approach has recently been used for significant and immediate pain reduction of some types of painful oral lesions such as recurrent aphthous stomatitis, pemphigus vulgaris, and so on. In this procedure by some considerations, the conventional CO2 laser is used as a non-surgical, non- thermal, photobiomodulative laser without any visible thermal adverse effects. In this article, we report our experiences about the analgesic effects of NTCLT on painful oral aphthous ulcers of BD. Case Presentation: We report four cases of BD, whose painful oral aphthous ulcers were irradiated with NTCLT. Immediately after NTCLT, the pain of the lesions was significantly relieved with no visible complications. Conclusion: The results of this study suggest that NTCLT could be proposed as a hopeful procedure for significant and instant pain relief of oral aphthous ulcers of BD without any visible thermal adverse effects.

scholarly journals Histopathological Evaluation of Behçet's Disease and Identification of New Skin Lesions

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Özgür Gündüz
Keyword(s):  
Differential Diagnosis ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Skin Lesions ◽  
Direct Immunofluorescence ◽  
Inflammatory Disorder ◽  
Behcet's Disease ◽  
Histopathological Evaluation ◽  
New Skin

Behçet's disease (BD) is a multisystemic, relapsing inflammatory disorder with an obscure etiology and pathogenesis. Diagnosis depends on the clinician's ability to identify a group of nonspecific mucocutaneous lesions, which also manifest in a number of other diseases. In recent years, there has been an increase in the studies focusing on the histopathological aspects of Behçet's disease diagnostic mucocutaneous lesions. Their results emphasize the value of histopathology and direct immunofluorescence (DIF) in the differential diagnosis of Behçet's disease.

scholarly journals One-Year Period Prevalence of Oral Aphthous Ulcers and Oral Health-Related Quality of Life in Patients with Behçet’s Disease

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Mariko Naito ◽  
Yoshimi Suzukamo ◽  
Kenji Wakai ◽  
Miki Azechi ◽  
Fumio Kaneko ◽  
...  
Keyword(s):  
Oral Health ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Control Group ◽  
Behcet's Disease ◽  
Aphthous Ulcers ◽  
Related Quality ◽  
Health Related

The aim of this study was to investigate the 1-year period prevalence of oral aphthous ulcers (OAUs) and their association with oral health-related quality of life (OHQOL) in patients with Behçet’s disease (BD) and in the general population. In this cross-sectional study, 675 patients with Behçet’s disease (BD group) and 1,097 males and females in the Japanese general population (control group) completed both questionnaires on their OAU status during the prior year and the General Oral Health Assessment Index (GOHAI). In the BD group, 84% of patients reported experiencing an OAU during the previous year, and the mean number of OAUs/year was 13. In the control group, 31% of individuals experienced an OAU during the previous year, and the mean number of OAUs/year was one. Multivariate analysis indicated that both BD patients (OR, 6.2; 95% CI, 4.8–8.0) and controls (OR, 2.6; 95% CI, 2.0–3.5) who had OAUs at least twice per year were more likely to have GOHAI scores below the norm than were controls who had fewer than two OAUs per year. The association between HLA-B*51 and OAUs remains unknown. The presence of OAUs has a negative effect on the OHQOL of patients with BD.

scholarly journals Brainstem astrocytoma as a neuro-Behçet’s disease mimic

2018 ◽  
Vol 11 (1) ◽  
pp. e226945
Author(s):  
Julia Manasson ◽  
Jonathan Howard ◽  
Johannes Nowatzky
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Correct Diagnosis ◽  
Brain Biopsy ◽  
Behcet's Disease ◽  
Unsteady Gait ◽  
Recurrent Aphthous Ulcers ◽  
Fluid Attenuated Inversion Recovery ◽  
Motor Dexterity

A 58-year-old man with a history of recurrent aphthous ulcers since childhood was admitted to the hospital with acute neurological decline characterised by loss of motor dexterity, dysarthria, dysphagia and unsteady gait. MRI brain was significant for symmetrical hyperintense T2 fluid attenuated inversion recovery (FLAIR) in the corticospinal tracts, including parts of the pons and the mesodiencephalic junction. Though initial concern was for neuro-Behçet’s disease, brain biopsy ultimately revealed a diagnosis of astrocytoma. This report demonstrates a mimic of neuro-Behçet’s disease and the importance of confirming the correct diagnosis prior to initiating therapy.

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