scholarly journals Polyunsaturated Fatty Acids, DNA Repair Single Nucleotide Polymorphisms and Colorectal Cancer in the Singapore Chinese Health Study

2009 ◽  
Vol 2 (6) ◽  
pp. 273-279 ◽  
Author(s):  
Mariana C. Stern ◽  
Lesley M. Butler ◽  
Román Corral ◽  
Amit D. Joshi ◽  
Jian-Min Yuan ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Fatty Acids ◽  
Dna Repair ◽  
Single Nucleotide Polymorphisms ◽  
Polyunsaturated Fatty Acids ◽  
Health Study ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Singapore Chinese

Single nucleotide polymorphisms in desaturases genes – effect on docosahexaenoic acid levels in maternal and fetal tissues and early development of the child.

2017 ◽  
Vol 86 (2) ◽  
pp. 177
Author(s):  
Malwina Anna Malinowska ◽  
Oskar Wojciech Wiśniewski ◽  
Magdalena Warchoł
Keyword(s):  
Fatty Acids ◽  
Single Nucleotide Polymorphisms ◽  
Polyunsaturated Fatty Acids ◽  
Infant Health ◽  
Birth Outcome ◽  
Genetic Profile ◽  
Nucleotide Polymorphisms ◽  
Dietary Recommendations ◽  
Single Nucleotide ◽  
Pregnancy And Lactation

Polyunsaturated fatty acids (PUFAs) beneficially affect an optimal fetal growth and development right after birth. This effect is particularly significant for the growth and maturation of brain. Therefore, an appropriate maternal regimens for PUFAs supplementation, during pregnancy and lactation, may influence birth outcome and infant health. Recently, it has been shown that genetic profile is an another factor determining long‑chain polyunsaturated fatty acids (LC‑PUFA) composition in human tissues. Single Nucleotide Polymorphisms (SNPs) in the fatty desaturase 1 and 2 (FADS1 and FADS2) modify endogenous synthesis of PUFAs indicating that PUFAs blood concentration may depend on genetic background. What is more, a number of studies indicate that maternal FADS gene variants by their influence on LC‑PUFAs synthesis are associated with child’s health right after birth as well as within first years of life. Determining individual dietary recommendations for clinical practice can be beneficial for both mother and the child.

Impact on response and survival of DNA repair single nucleotide polymorphisms in relapsed or refractory multiple myeloma patients treated with thalidomide

2011 ◽  
Vol 35 (9) ◽  
pp. 1178-1183 ◽  
Author(s):  
María Teresa Cibeira ◽  
Carlos Fernández de Larrea ◽  
Alfons Navarro ◽  
Tania Díaz ◽  
Dolors Fuster ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Dna Repair ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Refractory Multiple Myeloma

scholarly journals Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer

2010 ◽  
Vol 31 (8) ◽  
pp. 1381-1386 ◽  
Author(s):  
B. Frank ◽  
M. Hoffmeister ◽  
N. Klopp ◽  
T. Illig ◽  
J. Chang-Claude ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Single Nucleotide Polymorphisms ◽  
Wnt Signaling ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Cell Death Pathway

Deletion and Single Nucleotide Polymorphisms in Common Glutathione-S Transferases Contribute to Colorectal Cancer Development

2019 ◽  
Vol 25 (4) ◽  
pp. 1579-1587 ◽  
Author(s):  
Milica Lj. Stojkovic Lalosevic ◽  
Vesna M. Coric ◽  
Tatjana D. Pekmezovic ◽  
Tatjana P. Simic ◽  
Marija S. Pljesa Ercegovac ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Single Nucleotide Polymorphisms ◽  
Cancer Development ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Glutathione S Transferases

Association between single nucleotide polymorphisms in the DNA repair gene LIG3 and acute adverse skin reactions following radiotherapy

2011 ◽  
Vol 99 (2) ◽  
pp. 231-234 ◽  
Author(s):  
Robert J.S. Murray ◽  
George A. Tanteles ◽  
Jamie Mills ◽  
Angus Perry ◽  
Irene Peat ◽  
...  
Keyword(s):  
Dna Repair ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Repair Gene ◽  
Skin Reactions ◽  
Single Nucleotide ◽  
Dna Repair Gene
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