Fine-Needle Aspiration Cytology of Intranodal Palisaded Myofibroblastoma of the Inguinal Lymph Node

2016 ◽  
Vol 60 (1) ◽  
pp. 89-92 ◽  
Author(s):  
Jianwu Xie ◽  
Cufeng Pu ◽  
Jan F. Silverman
Keyword(s):  
Lymph Node ◽  
Fine Needle Aspiration ◽  
Single Cells ◽  
Needle Aspiration ◽  
Palpable Mass ◽  
Fine Needle ◽  
Acellular Matrix ◽  
Spindle Cells ◽  
Mesenchymal Neoplasm ◽  
Intranodal Palisaded Myofibroblastoma

Background: Intranodal palisaded myofibroblastoma (IPM) is a rare, lymph node mesenchymal neoplasm; the cytologic features are limited in the literature. Case: The patient was a 51-year-old female who had a firm, palpable mass in the right inguinal region. Fine-needle aspiration (FNA) was performed. The smears revealed large, 3-dimensional clusters of cohesive spindle cells, densely surrounding a central, orange-colored, acellular matrix core. These cells had a single, elongated nucleus and an inconspicuous nucleolus. Also seen were spindle cells in short fascicles with dense cytoplasm. The spindle cells were loosely arranged in a single-cell pattern. In addition to the spindle cells and matrix, hemosiderin granules were scattered in the background. A few lymphocytes were identified. Conclusion: A diagnosis of IPM should be considered when FNA smears of lymph node show bland spindle cells in various patterns including single cells, short fascicles, large cohesive clusters with core amianthoid fibers and background hemosiderin granules.

Ultrasound-Guided Fine-Needle Aspiration of Superficial Lymphadenopathy Performed by Interventional Pathologists: The Applicability of the Sydney System from 2 Years of Experience and 363 Cases

2021 ◽  
pp. 1-10
Author(s):  
Héctor Enrique Torres Rivas ◽  
Karen Villar Zarra ◽  
Lisseth Andrea Pérez Pabón ◽  
María de la Paz González Gutierréz ◽  
Nuria Zapico Ortiz ◽  
...  
Keyword(s):  
Lymph Node ◽  
Retrospective Study ◽  
Fine Needle Aspiration ◽  
Diagnostic Procedure ◽  
Needle Aspiration ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Specialized Hospital ◽  
Uncertain Significance ◽  
Sydney System

<b><i>Introduction:</i></b> The Sydney system proposal for the study and reporting of lymphadenopathy by fine-needle aspiration (FNA) constitutes one of the first attempts to standardize this procedure. Here, we review its applicability. <b><i>Materials and Methods:</i></b> A retrospective study in which all ultrasound-guided FNAs (USFNAs) of superficial lymphadenopathy (palpable or not) performed by interventional pathologists in 2 specialized hospital centers were quantified over 2 years. The procedure was systematized, and the diagnoses were reclassified according to the Sydney system categories. <b><i>Results:</i></b> We analyzed 363 USFNAs of lymphadenopathies. The distribution of cases by categories was as follows: insufficient (<i>n</i> = 13; 3.58%), benign (<i>n</i> = 208; 57.30%), atypia of uncertain significance (<i>n</i> = 7; 1.93%), suspicious (<i>n</i> = 21; 5.79), and malignant (<i>n</i> = 114; 31.40%). The risks of malignancy calculated for categories I, II, III, IV, and V were 27%, 3%, 50%, 100%, and 100%, respectively. <b><i>Conclusion:</i></b> The implementation of the Sydney system allows the systematization and standardization of the lymph node FNA methodology, with increased efficacy and efficiency. Assimilating the recommendations enables the qualification of the diagnostic procedure.

The Application of Fine Needle Aspiration Biopsy in the Diagnosis of Axillary Masses

2021 ◽  
pp. 1-7
Author(s):  
Cong-Gai Huang ◽  
Meng-Ze Li ◽  
Shao-Hua Wang ◽  
Xiao-Qin Tang ◽  
Johannes Haybaeck ◽  
...  
Keyword(s):  
Lymph Node ◽  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Benign Lesions ◽  
Fine Needle ◽  
Significant Difference ◽  
Malignant Lesions ◽  
Axillary Mass

<b><i>Introduction:</i></b> We intend to determine the diagnostic power of fine needle aspiration biopsy (FNAB) for differentiation between malignant and benign lesions on axillary masses and draw the physicians’ attention to the benefits of FNAB cytology in the diagnosis of axillary masses. <b><i>Methods:</i></b> In this study, 1,328 patients with an axillary mass diagnosed by FNAB were retrospectively reviewed. These cases were registered at the affiliated hospital of Southwest Medical University (China), July 2014 to June 2017. Cytological results were verified either by histopathology following surgical resection or clinical follow-up. <b><i>Results:</i></b> Of the 1,328 patients affected by axillary masses, 987 (74.3%) cases were female, and 341 (25.7%) cases were male. The highest incidence of patients was in the age group of 41–50 years (375, 28.2%). There were 1,129 (85.0%) patients with benign lesions and 199 (15.0%) with malignant lesions. Of the 199 malignant lesions cases, 21 cases were lymphomas, 2 cases were accessory breast cancers, and 176 cases were lymph node metastatic tumors. Under lymph node metastases, the most frequent primary tumors were breast cancer (141, 80.1%), followed by lung cancer (21, 11.9%). According to the study, the characters of 1,328 cases showed statistically significant difference (χ<sup>2</sup> = 4.534, <i>p</i> = 0.033), and the incidence of females with axillary mass was significantly higher than that of males. There was a statistically significant difference in the distribution of benign and malignant cases in the patient age groups (χ<sup>2</sup> = 1.129, <i>p</i> = 0.000), and the incidence of patients of 41–50 years of age was significantly higher than that of other patients. The diagnostic accuracy of FNAB in axillary masses was analyzed with the results of 95.98% of sensitivity, 99.56% of specificity, 97.45% of positive predictive value, and 99.29% of negative predictive value. <b><i>Conclusion:</i></b> Our results confirm that FNAB is a valuable initial screening method regarding pathologic diagnosis of axillary mass, in particular with respect to malignancy in 41- to 50-year-old female patients.

Fine-Needle Aspiration Effects on Benign Lymph Node Histology

1985 ◽  
Vol 133 (2) ◽  
pp. 350-350
Author(s):  
F.G. Behm ◽  
G.J. O’Dowd ◽  
W.J. Frable
Keyword(s):  
Lymph Node ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Lymph Node Histology ◽  
Benign Lymph Node

Correlation of Ultrasound Findings and Fine-Needle Aspiration Cytology for the Diagnosis of Axillary Lymph Node Metastasis in Patients with Breast Carcinoma

2018 ◽  
Vol 63 (1) ◽  
pp. 17-22
Author(s):  
Kusum Kapila ◽  
Preetha Alath ◽  
Govind H. Hebbar ◽  
Mohammed Jaragh ◽  
Sara S. George ◽  
...  
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Width Ratio ◽  
Axillary Lymph ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Length Width ◽  
Needle Aspiration Cytology

Objective: Ultrasound-guided fine-needle aspiration cytology (USG-FNAC) is used for the detection of axillary lymph node (ALN) metastasis in patients with breast carcinoma (BC). US findings have a good diagnostic accuracy with high sensitivity and specificity. The aim of this study is to correlate the detection of ALN metastases on US with FNAC in BC patients. Study Design: In 75 BC patients, over a period of 9 months (January to September 2017), the size, cortical thickness (CT), presence or absence of hilar fat, and length/width ratio of ALN on US were reviewed and correlated with FNAC findings. Results: The age range was 29–78 (mean 52) years. There were 38 patients with a single ALN and 37 with multiple ALNs. ALNs with a maximum length of > 2.5 cm were malignant in 100% of cases while those ≥1.5 cm were malignant in 80.4%. ALNs with a CT of > 3 mm had metastasis in 78.1% cases. ALNs with absent hilar fat showed tumour in 87.5% cases. A length/width ratio of < 2 showed a metastatic tumour in 66.7% of aspirates. Conclusion: An association was seen between metastatic carcinoma on FNAC and axillary US features of a maximum length of ≥1.5 cm, the absence of hilar fat, and a CT of > 3 mm (p < 0.05).

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