Vascular Refilling Is Not Reduced in Dialysis Sessions with Morbid Events

2017 ◽  
Vol 43 (4) ◽  
pp. 309-314 ◽  
Author(s):  
Susanne Kron ◽  
Daniel Schneditz ◽  
Til Leimbach ◽  
Sabine Aign ◽  
Joachim Kron
Keyword(s):  
Blood Volume ◽  
Normal Blood ◽  
Strongly Correlated ◽  
Patient Groups

Background: It is commonly believed that insufficient vascular refilling leads to hypovolemia during hemodialysis and contributes to intradialytic morbid events (IME). But data of refilling volumes at the time of IME are lacking. Methods: We compared the vascular refilling in 10 patients with IME with 14 stable patients with normal blood volume at the dialysis end (66-80 mL/kg). Results: The refilling characteristics in patients with IME did not differ from those in stable patients. The refilling fraction (refilling/ultrafiltration [UF] ratio) was 73.8 ± 9.4% in patients with IME, and 70.2 ± 6.4% in patients with normal blood volume at the end of the treatment. Refilling volume strongly correlated with UF volume in both patient groups (r2 = 0.93 and r2 = 0.81, respectively). Conclusion: IME are associated with a specific blood volume below 65 mL/kg. Vascular refilling is a constant fraction of UF in stable as well as in symptomatic dialysis sessions.

scholarly journals Blood Volume and Molybdenum Toxicity in Rabbits

Blood ◽  
1953 ◽  
Vol 8 (12) ◽  
pp. 1105-1106 ◽  
Author(s):  
JACK D. BURKE ◽  
L. R. ARRINGTON ◽  
G. K. DAVIS
Keyword(s):  
Body Weight ◽  
Blood Volume ◽  
Normal Blood ◽  
Normal Range

Abstract The blood volume of normal rabbits and rabbits anemic with molybdenum toxicity was determined using the dye and P32 methods. The blood volume per unit of body weight was found to be within the normal range indicating that rabbits were able to maintain normal blood volume even though anemic as a result of molybdenum toxicity.

scholarly journals Measuring the ratio of femoral vein diameter to femoral artery diameter by ultrasound to estimate volume status

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhihang Ma ◽  
Jiaxin Gai ◽  
Yinghan Sun ◽  
Yunpeng Bai ◽  
Hongyi Cai ◽  
...  
Keyword(s):  
Blood Volume ◽  
Femoral Artery ◽  
Roc Curve ◽  
Femoral Vein ◽  
Venous Pressure ◽  
Volume Status ◽  
Strongly Correlated ◽  
Central Venous ◽  
Test Characteristics ◽  
Vein Diameter

Abstract Background Currently, the accepted effective method for assessing blood volume status, such as measuring central venous pressure (CVP) and mean pulmonary artery pressure (mPAP), is invasive. The purpose of this study was to explore the feasibility and validity of the ratio of the femoral vein diameter (FVD) to the femoral artery diameter (FAD) for predicting CVP and mPAP and to calculate the cut-off value for the FVD/FAD ratio to help judge a patient’s fluid volume status. Methods In this study, 130 patients were divided into two groups: in group A, the FVD, FAD, and CVP were measured, and in group B, the FVD, FAD, and mPAP were measured. We measured the FVD and FAD by ultrasound. We monitored CVP by a central venous catheter and mPAP by a Swan-Ganz floating catheter. Pearson correlation coefficients were calculated. The best cut-off value for the FVD/FAD ratio for predicting CVP and mPAP was obtained according to the receiver operating characteristic (ROC) curve. Results The FVD/FAD ratio was strongly correlated with CVP (R = 0.87, P < 0.0000) and mPAP (R = 0.73, P < 0.0000). According to the ROC curve, an FVD/FAD ratio ≥ 1.495 had the best test characteristics to predict a CVP ≥ 12 cmH2O, and an FVD/FAD ratio ≤ 1.467 had the best test characteristics to predict a CVP ≤ 10 cmH2O. An FVD/FAD ratio ≥ 2.03 had the best test characteristics to predict an mPAP ≥ 25 mmHg. According to the simple linear regression curve of the FVD/FAD ratio and CVP, when the predicted CVP ≤ 5 cmH2O, the FVD/FAD ratio was ≤ 0.854. Conclusion In this study, the measurement of the FVD/FAD ratio obtained via ultrasound was strongly correlated with CVP and mPAP, providing a non-invasive method for quickly and reliably assessing blood volume status and providing good clinical support.

scholarly journals Increased hippocampal blood volume and normal blood flow in schizophrenia

2015 ◽  
Vol 232 (3) ◽  
pp. 219-225 ◽  
Author(s):  
Pratik Talati ◽  
Swati Rane ◽  
Jack Skinner ◽  
John Gore ◽  
Stephan Heckers
Keyword(s):  
Blood Flow ◽  
Blood Volume ◽  
Normal Blood ◽  
Normal Blood Flow

Pressure-volume curves in live, intact dogs

1961 ◽  
Vol 201 (3) ◽  
pp. 471-474 ◽  
Author(s):  
Travis Q. Richardson ◽  
James O. Stallings ◽  
Arthur C. Guyton
Keyword(s):  
Blood Volume ◽  
Normal Blood ◽  
Control Value ◽  
The Mean ◽  
Major Factors ◽  
Blood Volumes

The effect of changes in blood volume on mean circulatory pressure was studied in 10 dogs. Mean circulatory pressure increased linearly as the blood volume was expanded and decreased linearly as blood volume was lowered below the normovolemic level. For example, the mean circulatory pressure fell from a normal of 7 mm Hg down to 0 mm Hg when the animals were rapidly hemorrhaged 14.7% of their normal blood volume; when the blood volumes were expanded to 50% above normal, the mean circulatory pressure rose from the control value of 7 mm Hg up to 30 mm Hg. It is concluded that one of the major factors determining the mean circulatory pressure is blood volume.

A Pilot Study of the Snap & Sniff Threshold Test

2018 ◽  
Vol 127 (5) ◽  
pp. 312-316
Author(s):  
Rong-San Jiang ◽  
Kai-Li Liang
Keyword(s):  
Pilot Study ◽  
Correlation Coefficient ◽  
Strongly Correlated ◽  
Olfactory Threshold ◽  
Retest Reliability ◽  
Threshold Test ◽  
Patient Groups ◽  
The Mean ◽  
Test Retest Reliability ◽  
Olfactory Thresholds

Objectives: The Snap & Sniff® Threshold Test (S&S) has been recently developed to determine the olfactory threshold. The aim of this study was to further evaluate the validity and test–retest reliability of the S&S. Methods: The olfactory thresholds of 120 participants were determined using both the Smell Threshold Test (STT) and the S&S. The participants included 30 normosmic volunteers and 90 patients (60 hyposmic, 30 anosmic). The normosmic participants were retested using the STT and S&S at an intertest interval of at least 1 day. Results: The mean olfactory threshold determined with the S&S was −6.76 for the normosmic participants, −3.79 for the hyposmic patients, and −2 for the anosmic patients. The olfactory thresholds were significantly different across the 3 groups ( P < .001). Snap & Sniff–based and STT-based olfactory thresholds were correlated weakly in the normosmic group (correlation coefficient = 0.162, P = .391) but more strongly correlated in the patient groups (hyposmic: correlation coefficient = 0.376, P = .003; anosmic: correlation coefficient = 1.0). The test–retest correlation for the S&S-based olfactory thresholds was 0.384 ( P = .036). Conclusion: Based on validity and test–retest reliability, we concluded that the S&S is a proper test for olfactory thresholds.

scholarly journals Willebrand factor in hemostasis in the in vitro bleeding time

Blood ◽  
1979 ◽  
Vol 54 (6) ◽  
pp. 1347-1357 ◽  
Author(s):  
A Kimura ◽  
EJ Bowie ◽  
RJ Campbell ◽  
DN Fass
Keyword(s):  
Blood Volume ◽  
Bleeding Time ◽  
Normal Blood ◽  
In Vitro System ◽  
Skin Changes ◽  
Incision Site ◽  
Flow Through ◽  
Von Willebrand ◽  
Willebrand Factor

Abstract Heparinized porcine blood and plasma, at constant hydrostatic pressure, was allowed to flow through a 5-mm incision in a small piece of porcine skin. Changes in the exuded blood volume were measured, and the incision site was examined microscopically. When normal blood flowed through either normal or von Willebrand skin, the exuded blood volume decreased gradually and eventually stopped. Microscopic examination revealed a platelet plug in the incision site. This plug was positive for Willebrand factor when examined by immunofluorescence. In contrast, the blood from von Willebrand pigs continued to flow constantly, and a platelet plug was not seen. The delayed in vitro hemostasis in von Willebrand blood was corrected to the normal range by the addition of either normal plasma or partially purified Willebrand factor. Normal blood, in which the Willebrand factor was immunologically inhibited, showed delayed hemostasis. For this in vitro system, it appeared that plasmatic Willebrand factor played an essential role in hemostasis.

Sign in / Sign up

Export Citation Format

Share Document