scholarly journals Central Airway Obstruction due to Mediastinal Malignant Lymphoma Requiring Venovenous-Extracorporeal Membrane Oxygenation

2019 ◽  
Vol 2 (2) ◽  
pp. 42-47 ◽  
Author(s):  
Yoshihiro Ueda ◽  
Ichiro Hirayama ◽  
Ryohei Horie ◽  
Kent Doi ◽  
Naoto Morimura

Extracorporeal membrane oxygenation (ECMO) therapy might be controversial when patients with advanced malignant disease develop heart or lung failure refractory to conventional management. Especially as for the hematological malignancy patients, the induction of ECMO therapy must be considered carefully, since it is often associated with bleeding complications or infectious diseases. Here, we report a case of life-threatening airway obstruction requiring ECMO. The trachea of the patient was narrowed by an anterior mediastinal tumor too highly to ventilate both lungs, so she had to be connected to venovenous-ECMO (VV-ECMO) before pathological examination and radical treatment were planned. During the intensive care with ECMO, she was diagnosed with malignant lymphoma and the chemotherapy was started. The chemotherapy brought such an immediate result that the trachea regained its patency and ECMO was disconnected 9 days after the initiation of the chemotherapy. Then, the patient was able to leave the intensive care unit with no sequelae. Central airway obstruction is a life-threatening situation, in which prompt decisions are essential. On the other hand, if the airway is impaired by hematological malignancy, it might be generally challenging to consider ECMO as a bridge until the chemotherapy takes an effect. The prognosis of hematological malignancy differs according to its subtype or stage, so it may be reasonable to take ECMO therapy into consideration for some population.

2018 ◽  
Vol 42 (5) ◽  
pp. 317-319
Author(s):  
M. Ramírez-Romero ◽  
B. Hernández-Alonso ◽  
C. García-Polo ◽  
A.J. Abraldes-Bechiarelli ◽  
A. Garrino-Fernández ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Sabrina Meyer ◽  
Anne-Sophie Dincq ◽  
Lionel Pirard ◽  
Sebahat Ocak ◽  
Jean-Paul D’Odémont ◽  
...  

Purpose. Airway stenting offers good palliation and improves the quality of life in patients with inoperable bronchotracheal stenosis. However, in some cases, the management of stenting can be life-threatening. Hence, a strategy for maintaining oxygenation and hemodynamic stability should be anticipated to avoid critical situations. Herein, we report the use of extracorporeal membrane oxygenation (ECMO) in bronchotracheal stenting management to secure oxygenation and facilitate interventions. Methods. We retrospectively reviewed all patients who underwent rigid bronchoscopy under ECMO support for the management of bronchotracheal stenting at CHU UCL Namur hospital (Belgium), between January 2009 and December 2019. Results. We included 14 bronchoscopy cases performed on 11 patients (3 patients underwent 2 bronchoscopies) in this study; 12 were performed on males and 2 on females. The median age was 54 years. There were 11 benign and 3 malignant etiologies for the central airway obstruction/stenosis. Eight cases were supported by venovenous ECMO and six by venoarterial ECMO. The median ECMO time was 267 minutes. The weaning of ECMO support was successful in all cases. In most cases, the procedures were performed effectively and safely. Only two local complications caused by the cannulation of ECMO were reported, and anticoagulation was adapted to avoid bleeding at the operating site and clot formation in the system. Conclusion. Elective ECMO support was helpful and safe for the high-risk management of bronchotracheal stenting with rigid bronchoscopy and was not associated with any additional significant complications.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Albert Youngwoo Jang ◽  
Young Jun Oh ◽  
Seok In Lee ◽  
Oh Kyung Lim ◽  
Soon Yong Suh

Abstract Background Although life-threatening complications of extracorporeal membrane oxygenation (ECMO) are well described, non-life threatening complications are less known. Herein, we report a case of femoral neuropathy (FN) due to nerve compression caused by cannula compression and deep vein thrombosis (DVT) after successful ECMO therapy, which seriously undermined one’s quality of life. Case presentation A 70-year old male presented to the emergency department for chest pain. The patient had cardiac arrest before percutaneous coronary intervention (PCI) and was inserted with ECMO. Although he was successfully weaned from ECMO 4 days after PCI, he consistently complained swelling, abnormal sensation, and weakness in his right lower extremity, where the cannulas were inserted. Imaging studies showed deep vein thrombosis (DVT) in his right leg, which was further treated with anticoagulants. Symptoms, however, remained after the regression of DVT. Nerve conduction study revealed femoral neuropathy, which may have been caused by ECMO cannula compression and tissue swelling. Conclusion The current case proposes that non-life threatening complications of ECMO therapy can seriously affect quality of life. Venous drainage distant from the arterial cannula may prevent such complications.


Perfusion ◽  
2017 ◽  
Vol 33 (4) ◽  
pp. 320-322 ◽  
Author(s):  
Sean P. Kane ◽  
Elliott Cohen

Hydrochlorothiazide has been shown to cause rare, but serious non-cardiogenic pulmonary edema. We present a case report of a patient with apparent septic shock and acute respiratory distress syndrome (ARDS) requiring life-sustaining veno-venous extracorporeal membrane oxygenation (VV-ECMO). Upon further review of the literature and the chronology of the patient’s presentation, her condition was most likely due to an immune-mediated reaction to hydrochlorothiazide. This represents the first case, to our knowledge, of such a severe reaction to hydrochlorothiazide supported with ECMO therapy.


2020 ◽  
Author(s):  
Binbin Ren ◽  
Qing Wang ◽  
Hongying Ni ◽  
Jie Chang ◽  
Kun Chen ◽  
...  

Abstract Background: Clot formation along airway can lead to airway obstruction, causing life-threatening condition to the patient. However, blood from the oral cavity flowing down the endotracheal tube and forming a giant blood clot in the airway is rarely reported.Case presentation: Here we present a case of central airway obstruction by a blood clot due to tonsil bleeding, which was managed with timely procedure. Conclusions:The case do give us further educational meaning when such patient presented.


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