scholarly journals Endoscopic Resection of a Pedunculated Cavernous Hemangioma of the Sigmoid Colon: A Case Report

2019 ◽  
Vol 13 (3) ◽  
pp. 418-422
Author(s):  
Naotaka Ogasawara ◽  
Manami Suzuki ◽  
Kazunori Adachi ◽  
Yoshiharu Yamaguchi ◽  
Sayuri Yamamoto ◽  
...  
Keyword(s):  
Sigmoid Colon ◽  
Cavernous Hemangioma ◽  
Histopathological Examination ◽  
Narrow Band Imaging ◽  
Submucosal Tumor ◽  
Benign Tumors ◽  
Normal Colonic Mucosa ◽  
Negative Resection Margin ◽  
Basal Portion ◽  
Snare Polypectomy

Hemangiomas are common benign tumors that usually occur on the head and neck in children. However, colonic hemangiomas are rare in clinical practice. Approximately 80% of colonic hemangiomas are of the cavernous type, and morphologically, ≥80% of colonic hemangiomas are sessile and semi-pedunculated. Notably, pedunculated colonic hemangiomas are rare. A 69-year-old woman presented with hematochezia and underwent colonoscopy, which revealed a soft pedunculated submucosal tumor (SMT) measuring 1.5 cm in diameter, in the sigmoid colon. The surface of the SMT resembled the surrounding normal colonic mucosa with regard to color and appearance, with multiple red patches. Narrow-band imaging revealed a few telangiectasias on the surface of the SMT. The lesion could not be definitively diagnosed based on endoscopic findings. Therefore, for more accurate diagnosis, the SMT was removed by snare polypectomy with electrocautery after clipping the basal portion of the tumor stalk for prophylactic hemostasis. Histopathological examination of the specimen revealed a cavernous hemangioma with a negative resection margin. We report a case of a pedunculated cavernous hemangioma of the sigmoid colon removed by snare polypectomy with electrocautery after clipping the basal portion of the tumor stalk for prophylactic hemostasis.

scholarly journals A rare case of adrenal cavernous hemangioma

2020 ◽  
Vol 73 (3-4) ◽  
pp. 101-103
Author(s):  
Ivo Vujicik
Keyword(s):  
Computed Tomography ◽  
Cavernous Hemangioma ◽  
Histopathological Examination ◽  
Benign Tumors ◽  
Sinusoidal Dilatation ◽  
Radiologic Findings ◽  
Iodinated Contrast ◽  
Microscopic Evaluation ◽  
Cavernous Hemangiomas ◽  
Postoperative Diagnosis

Introduction. Adrenal cavernous hemangiomas are extremely rare non-functioning benign tumors. The majority of adrenal cavernous hemangiomas are diagnosed incidentally after surgery by histopathological examination. Case Report. We report a clinical case of a 57-year-old woman with adrenal cavernous hemangioma. On admission, the patient?s adrenal-related hormones were in the reference range, so adrenal endocrine dysfunction was ruled out. The computed tomography scan revealed a well-circumscribed, round, heterogeneous right adrenal mass (32.3 x 55.4 mm). Iodinated contrast enhanced abdominal computed tomography showed a slight inhomogeneity. In this case, preoperative radiologic findings and absence of signs of local invasion indicated laparoscopic adrenalectomy. The patient underwent right transperitoneal adrenalectomy. Microscopic evaluation showed a sinusoidal dilatation and fibrotic septa, so postoperative diagnosis of adrenal cavernous hemangioma was made. Conclusion. In summary, we reported a case of an incidentally discovered non-functioning adrenal cavernous hemangioma treated by laparoscopic surgery. The diagnosis of adrenal cavernous hemangioma may be challenging, and it is commonly made after surgery, since it is frequently confirmed by histopathological examination.

scholarly journals A case of appendiceal ganglioneuroma in neurofibromatosis type 1

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Tadaaki Shimizu ◽  
Nao Hondo ◽  
Yusuke Miyagawa ◽  
Masato Kitazawa ◽  
Futoshi Muranaka ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Neurofibromatosis Type 1 ◽  
Histopathological Examination ◽  
Submucosal Tumor ◽  
Fibrous Tissue ◽  
Neurofibromatosis Type ◽  
Inherited Disease ◽  
Negative Resection Margin ◽  
Neurogenic Tumors

Abstract Background Neurofibromatosis type 1 is an autosomal dominant inherited disease associated with multiple skin neurofibromas or other neurogenic tumors, such as nodular plexiform neurinoma or cerebrospinal tumor. Gastrointestinal stromal tumors are often complicated in patients with neurofibromatosis type 1, although involvement of the appendix is rare, and there have been few reports of appendiceal ganglioneuroma. Case presentation The patient was a 29-year-old man diagnosed with neurofibromatosis type 1 based on physical findings and his family history. During the follow-up of neurofibromatosis, computed tomography was performed to detect neurological tumors, such as neurofibromas in the brain, spinal cord, and gastrointestinal tract. Computed tomography showed a markedly thickened appendix wall, and an appendiceal tumor was suspected. Laparoscopic appendectomy was performed, and a 50 × 35 mm appendiceal submucosal tumor was resected with a negative resection margin. At histopathological examination, the tumor was diagnosed as ganglioneuroma; it showed short spindle-shaped cells and ganglion cells diffusely infiltrated into the proper muscle layer and fibrous tissue that grew around nerve cells. The patient was discharged on the 5th postoperative day without postoperative complications and was doing well at 13 months following the operation. Conclusions Gastrointestinal stromal tumor and neurofibroma are the most common gastrointestinal tumors associated with neurofibromatosis type 1, but ganglioneuroma of the appendix is rare. Appendiceal neurogenic tumors should be considered in patients with neurofibromatosis type 1, and surgical resection is necessary because of the risk of malignancy.

Esophageal Adenocarcinoma with Enteroblastic Differentiation Arising in Ectopic Gastric Mucosa in the Cervical Esophagus: a Case Report and Literature Review

2017 ◽  
Vol 26 (2) ◽  
pp. 193-197 ◽  
Author(s):  
Ryosuke Gushima ◽  
Rei Narita ◽  
Takashi Shono ◽  
Hideaki Naoe ◽  
Takashi Yao ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Esophageal Adenocarcinoma ◽  
Histopathological Examination ◽  
Narrow Band Imaging ◽  
Carbohydrate Antigen ◽  
Endoscopic Examination ◽  
Ectopic Gastric Mucosa ◽  
Tubular Adenocarcinoma ◽  
Positron Emission ◽  
Elevated Lesion

Background: Adenocarcinoma with enteroblastic differentiation is a subtype of alpha-fetoprotein (AFP) producing adenocarcinoma. This type of tumor is associated with a poor prognosis and is prone to metastasize. Esophageal adenocarcinoma with enteroblastic differentiation is extremely rare.Case presentation: The patient was a 65-year-old woman who was referred to our hospital with dysphagia. Endoscopic examination revealed an elevated lesion 20mm in diameter at 17cm from the upper incisors. Endoscopic submucosa dissection (ESD) was performed and histopathological examination revealed tubular adenocarcinoma composed of cuboidal cells with clear cell cytoplasm. Immunohistochemical stain was diffusely positive for Sall-like protein 4 (SALL4) and weakly positive for AFP and glypican 3. From this result, we diagnosed esophageal adenocarcinoma with enteroblastic differentiation. The patient is still alive without recurrence of cancer 40 months after ESD.Conclusion: To our knowledge, this is the first report to undergo ESD for esophageal adenocarcinoma with enteroblastic differentiation arising from ectopic gastric mucosa in the esophagus.Abbreviations: AFP: alfa-fetoprotein; CA19-9: carbohydrate antigen 19-9; CEA: carcinoembryonic antigen; ESD: endoscopic submucosal dissection; EUS: endoscopic ultrasound; FDG-PET: [18F] fluorodeoxyglucose positron emission tomography; ME: magnifying endoscopy; NBI: narrow band imaging; SALL 4: Sall-like protein 4; SCC: squamous cell carcinoma antigen.

scholarly journals Filiform polyposis with sigmoid colon adenocarcinoma: a case report

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Takayuki Okuno ◽  
Takamitsu Kanazawa ◽  
Hirohisa Kishi ◽  
Hiroyuki Anzai ◽  
Koji Yasuda ◽  
...  
Keyword(s):  
Sigmoid Colon ◽  
Colon Adenocarcinoma ◽  
Resected Specimen ◽  
Normal Colonic Mucosa ◽  
Histological Findings ◽  
P53 Expression ◽  
History Of ◽  
Reparative Process ◽  
Inflammatory Polyposis ◽  
Filiform Polyposis

Abstract Background Filiform polyposis is a rare form of inflammatory polyposis, which is occasionally formed in the colon of patients with history of inflammatory bowel disease (IBD). It is characterized by presence of several to hundreds of slender, worm-like polyps in the colon lined by histologically normal colonic mucosa and often coalesce, resulting in a tumor-like mass. Filiform polyposis is most frequently associated with a post-inflammatory reparative process in patients with IBD history, and only cases of filiform polyposis occurring in patients without IBD history have been reported. Filiform polyposis has been considered as a benign inflammatory polyposis without any risk of dysplasia, while the possibility of carcinogenesis of inflammatory polyps is not fully excluded. To date, only three cases of filiform polyposis coexisting with dysplasia have been reported. Case presentation A 59-year-old male patient with no past medical history of IBD underwent laparoscopic sigmoidectomy for obstructive filiform polyposis, which was associated with sigmoid colon adenocarcinoma. Based on the histological findings of the resected specimen, invasive sigmoid colon adenocarcinoma was surrounded by filiform polyposis, and adenocarcinoma also scattered uniformly on the surface of filiform polyposis. In immunohistochemistry, abnormal p53 expression was observed in adenocarcinoma, while it was not shown in mucosa on filiform polyposis. Conclusions This is the fourth case of filiform polyposis that is closely associated with colon dysplasia or adenocarcinoma based on histological findings. However, immunohistochemical findings did not support the theory that inflammation initiates adenocarcinoma in filiform polyposis like IBD. Hence, further immunohistochemical and genetic analyses are needed to clarify the association between filiform polyposis and carcinogenesis.

scholarly journals Solitary Amyloidosis of the Sigmoid Colon Featuring Submucosal Tumor Caused Hematochezia

2013 ◽  
Vol 52 (22) ◽  
pp. 2523-2527 ◽  
Author(s):  
Naotaka Ogasawara ◽  
Wataru Kitagawa ◽  
Konen Obayashi ◽  
Yoshitsugi Itoh ◽  
Hisatsugu Noda ◽  
...  
Keyword(s):  
Sigmoid Colon ◽  
Submucosal Tumor

A Case of Incidentally Detected Bladder Lipoma and a Review of the Literature

2021 ◽  
Vol 17 ◽  
Author(s):  
Emre Emekli ◽  
Elif Gündoğdu
Keyword(s):  
Histopathological Examination ◽  
Adrenal Adenoma ◽  
Bladder Wall ◽  
Benign Tumors ◽  
Imaging Features ◽  
Multiplanar Reconstructions ◽  
Clinical Presentations ◽  
Pelvic Lipomatosis ◽  
One Year

Background: Lipomas are benign fatty tumors made of fat tissue. Bladder lipomas are extremely rare. For this reason, it is necessary to be aware of the imaging features when incidentally detected in imaging. Case Report: In the abdominal computed tomography (CT) performed as part of the follow-up examination of a 43-year-old patient, who had undergone surgery for adrenal adenoma five years earlier, a 14x9x8 mm smoothly marginated, ovoid-shaped, hypodense mass lesion with a homogeneous internal structure was detected in the anterior bladder wall. The pre-contrast density of the lesion was measured as -105 HU. The magnetic resonance imaging performed one year after the CT examination revealed a 14x9x8 intramural mass in the bladder wall, showing protrusion toward the lumen. The group was observed to be markedly hypointense on fat-suppressed T1 and T2-weighted images and considered consistent with a bladder lipoma. Discussion: Bladder lipomas are benign lesions that can vary in clinical presentations but usually cause hematuria. The differential diagnosis of bladder lipomas includes other mesenchymal rare benign tumors that can arise from the urinary bladder submucosal layer, including leiomyoma, hemangioma, plasmacytoma, fibroma, and neurofibroma, in imaging bladder lipomas present as homogeneous lesions containing macroscopic fat. Only the liposarcoma and pelvic lipomatosis could also show similar features. The less differentiated liposarcomas tend to present more heterogeneous enhancement, irregular-shaped margins, and infiltrative behavior. Also, appropriate multiplanar reconstructions may allow the radiologist to determine it is an extravesical pelvic lipomatosis. Conclusion: Using CT and MRI, these lesions rich in adipose tissue can be distinguished from other lesions, and their diagnosis can be made to a great extent. However, a histopathological examination is required for a definitive diagnosis.

scholarly journals Submucosal cavernous hemangioma of the esophagus. the rare clinical case of endoscopic diagnosis and treatment by the endoscopic submucosal dissection method (esd)

2019 ◽  
Vol 1 (7) ◽  
pp. 33-40
Author(s):  
V.A. Yakovenko ◽  
A.M. Kiosov ◽  
A.A. Denisenko ◽  
V.P. Kovalenko ◽  
S.V. Fen
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Cavernous Hemangioma ◽  
Clinical Case ◽  
Submucosal Tumor ◽  
Integrated Approach ◽  
University Hospital ◽  
Vascular Neoplasm ◽  
Submucosal Dissection ◽  
Endoscopic Method ◽  
Upper Third

The cavernous esophagus hemangiomais a rare, benign vascular neoplasm of the esophagus, which is asymptomatic and can be detected by chance during diagnostic video gastroscopy.The aim ofthe study is to describe in the rare clinical case of diagnosis and an integrated approach in choosing an endoscopic method of treating a submucosal benign vascular neoplasm of the esophagus (cavernous hemangioma).Material and method. A 46-year-old patient was sent to the University Hospital of ZSMU to conduct video esophagogastroduodenoscopy in order to examine and select the treatment method for the submucosaltumor of the upper third of the esophagus found in one of the city’s clinics.Results. A comprehensive examination of the patient with a submucosal neoplasm of the upper third of the esophagus, including video esophagogastroscopy with high-resolution endoscopes (EGD), endoscopic ultrasonography (EUS), and computer-aided tomography (CT) were performed. At the EGD a submucosal tumor was reviled in the upper third of the esophagus. It was bluish in color, had a wide base, 3cm in length and 2cm in height, movable, with soft-elastic consistency. EUS revealed that the tumor is not associated with the muscular layer, has many small vessels. The structure of the neoplasm was hypoechoic, inhomogeneous due to the inclusion of calcinates. On CT scan a rounded tumor was found in the lumen of the upper third of the esophagus, 20x15x30mm in size, with clear and even margins, homogeneous structure with a single calcinate in the structure was found. The patient was underwent of endoscopic surgery. The tumor was removed by the endoscopic submucosal dissection (ESD).Conclusion. Cavernous esophagus hemangioma is a rare vascular submucosal neoplasm of the esophagus, which is usually asymptomatic, but has a great potential for complications such as bleeding, which is sometimes fatal. Timely diagnosis and minimally invasive endoscopic treatment methods are the prevention of complications and the treatment of choice for the treatment of esophageal submucoustumors.

scholarly journals Solitary Schwannoma on the Hypothenar Region of the Hand: A Literature Review

2020 ◽  
Vol 5 (10) ◽  
pp. 449-452
Author(s):  
Kastanis G ◽  
Kapsetakis P ◽  
Magarakis G ◽  
Bachlitzanaki M ◽  
Christoforidis C ◽  
...  
Keyword(s):  
Literature Review ◽  
Clinical Diagnosis ◽  
Peripheral Nerves ◽  
Histopathological Examination ◽  
Final Diagnosis ◽  
Benign Tumors ◽  
Rare Manifestation ◽  
Histopathological Evidence ◽  
Volar Surface

Schwannomas or neurilemmomas are the most common benign tumors of the neural sheaths of the peripheral nerves. Incidence of these tumors in the hand accounts to 0.8-2%. The majority of them appear as an isolated grown mass along the route of the nerves. Peripheral nerves benign tumors present many difficulties concerning the clinical diagnosis and only histopathological evidence provides the final diagnosis. In this case study, we present a 45 year old man with a grown asymptomatic mass on the volar surface of right hand (hypothenar) remained for two years and impinging the skin of the hand only the last months. Initial MRI results diagnosed the mass as gaglion cyst. Histopathological examination revealed a schwannoma. We present this case as a rare manifestation of a schwannoma in hypothenar area of the hand. A literature review of diagnoses and therapeutic management is also presented.

scholarly journals Long segment cervicothoracic intramedullary dermoid with concomitant conal lesion – A case report

2020 ◽  
Vol 11 ◽  
pp. 268
Author(s):  
Andrew Aranha ◽  
Pankaj Kumar ◽  
Ajay Choudhary ◽  
Purnima Paliwal
Keyword(s):  
Histopathological Examination ◽  
Case Reports ◽  
Benign Tumors ◽  
Resonance Imaging ◽  
Tumor Capsule ◽  
Neural Tissues ◽  
History Of ◽  
Intramedullary Dermoid Cyst ◽  
Similar Intensity ◽  
Surgical Extirpation

Background: Spinal dermoid cysts are benign tumors that result from congenital or acquired ectodermal inclusions. Long segment intramedullary involvement of the spinal cord is exceedingly rare, and there are only a handful of case reports found in the literature. Case Description: A 30-year-old female presented with a 3-month history of myelopathy characterized by progressive quadriparesis and urinary incontinence. Magnetic resonance imaging revealed multifocal heterogeneous intramedullary masses extending from C2 to T4 and at T12–L1 with similar intensity lesions seen within the central cord from T5 to T11 level. Following tumor decompression, she showed significant improvement in neurological function 1 month later. The histopathological examination confirmed the diagnosis of a multifocal intramedullary dermoid cyst. Conclusion: Partial surgical extirpation is a reasonable treatment for long segment intramedullary dermoid cysts, particularly when the tumor capsule is adherent to critical adjacent neural tissues.

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