scholarly journals Dynamic Serosal Perfusion Assessment during Colorectal Resection Using Visible Light Spectroscopy

2021 ◽  
pp. 1-7
Author(s):  
Alexander Gräfitsch ◽  
Philipp Kirchhoff ◽  
Savas D. Soysal ◽  
Silvio Däster ◽  
Henry Hoffmann

<b><i>Introduction:</i></b> Anastomotic leakage (AL) in colorectal surgery occurs with an incidence of up to 20%. Bowel perfusion is deemed to be one of the most important factors for anastomotic healing. However, not much is known about its variability during colorectal surgery and its impact on the outcome. Therefore, this study aims to evaluate serosal oxygen saturation patterns during colorectal resections with visible light spectroscopy (VLS). <b><i>Materials and Methods:</i></b> Bowel perfusion in patients undergoing left-sided colorectal resections was assessed at different timepoints during surgery using VLS on the colonic serosa. The primary outcome parameter was serosal oxygen saturation (StO<sub>2</sub>) at the anastomosis during different timepoints of surgery. <b><i>Results:</i></b> We included 50 patients who underwent colorectal resection for bowel cancer (58%) and diverticular disease (34%). StO<sub>2</sub> at the proximal site of the anastomosis increased significantly throughout the surgery (mean difference 3.61%; 95% CI –6.22 to –1.00; <i>p</i> = 0.008). However, aberrancy from this identified perfusion pattern had no impact on the postoperative outcome. <b><i>Conclusion:</i></b> During colorectal resections, we could demonstrate an increase of the colonic StO<sub>2</sub> throughout surgery. Appearance of AL was not associated with lower StO<sub>2</sub>, underlining the multifactorial genesis of developing AL.

2017 ◽  
Vol 41 (11) ◽  
pp. 2923-2932 ◽  
Author(s):  
Henry Hoffmann ◽  
Tarik Delko ◽  
Philipp Kirchhoff ◽  
Rachel Rosenthal ◽  
Juliane Schäfer ◽  
...  

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Peter Tschann ◽  
Nikola Vitlarov ◽  
Martin Hufschmidt ◽  
Daniel Lechner ◽  
Paolo N. C. Girotti ◽  
...  

Abstract Introduction Endometriosis is associated with a high number of chronic pelvic pain and reduced quality of life. Colorectal resections in case of bowel involvement of endometriosis are associated with an unneglectable morbidity in young and healthy patients. There is no linear correlation established between the degree of symptoms and stage of endometriosis. The aim of this study was to correlate the histological findings to preoperative pain scores in colorectal resected patients with endometriosis. Methods Twenty-five patients who underwent laparoscopic colorectal resection for endometriosis between 2014 and 2019 were included in this retrospective study. Pain level was assessed preoperatively and postoperatively via phone call in May 2020. Histopathology was correlated to preoperative symptoms and postoperative outcome. Results Average follow-up time was 38.68 months (± 19.92). Preoperative VAS-score was 8.32 (± 1.70). We observed a significant reduction of pain level in all patients after surgery (p ≤ 0.005). Pain levels were equal regarding the presence of satellite spots and various degrees of infiltration depth. The resection margins were clear in all patients. Postoperative complications occurred in 6 cases (24%) and anastomotic leakage was observed in 3 patients (12%). Average VAS-score at time of follow-up was 1.70 (± 2.54). Conclusion Our data demonstrate that adequate colorectal resection leads to reduction of pain and an increase of quality of life irrespective of histopathological findings. An experienced team is necessary to improve intraoperative outcome and to reduce postoperative morbidity in case of complication.


2012 ◽  
Vol 112 (1) ◽  
pp. 26-32 ◽  
Author(s):  
Shunsaku Koga ◽  
Yutaka Kano ◽  
Thomas J. Barstow ◽  
Leonardo F. Ferreira ◽  
Etsuko Ohmae ◽  
...  

The overarching presumption with near-infrared spectroscopy measurement of muscle deoxygenation is that the signal reflects predominantly the intramuscular microcirculatory compartment rather than intramyocyte myoglobin (Mb). To test this hypothesis, we compared the kinetics profile of muscle deoxygenation using visible light spectroscopy (suitable for the superficial fiber layers) with that for microvascular O2 partial pressure (i.e., PmvO2, phosphorescence quenching) within the same muscle region (0.5∼1 mm depth) during transitions from rest to electrically stimulated contractions in the gastrocnemius of male Wistar rats ( n = 14). Both responses could be modeled by a time delay (TD), followed by a close-to-exponential change to the new steady level. However, the TD for the muscle deoxygenation profile was significantly longer compared with that for the phosphorescence-quenching PmvO2 [8.6 ± 1.4 and 2.7 ± 0.6 s (means ± SE) for the deoxygenation and PmvO2, respectively; P < 0.05]. The time constants (τ) of the responses were not different (8.8 ± 4.7 and 11.2 ± 1.8 s for the deoxygenation and PmvO2, respectively). These disparate (TD) responses suggest that the deoxygenation characteristics of Mb extend the TD, thereby increasing the duration (number of contractions) before the onset of muscle deoxygenation. However, this effect was insufficient to increase the mean response time. Somewhat differently, the muscle deoxygenation response measured using near-infrared spectroscopy in the deeper regions (∼5 mm depth) (∼50% type I Mb-rich, highly oxidative fibers) was slower (τ = 42.3 ± 6.6 s; P < 0.05) than the corresponding value for superficial muscle measured using visible light spectroscopy or PmvO2 and can be explained on the basis of known fiber-type differences in PmvO2 kinetics. These data suggest that, within the superficial and also deeper muscle regions, the τ of the deoxygenation signal may represent a useful index of local O2 extraction kinetics during exercise transients.


2010 ◽  
Vol 47 (1) ◽  
pp. 116-118 ◽  
Author(s):  
Marcelo Averbach ◽  
Pedro Popoutchi ◽  
Oswaldo Wiliam Marques Jr ◽  
Ricardo Z Abdalla ◽  
Sérgio Podgaec ◽  
...  

Laparoscopic colorectal surgery is believed to be technically and oncologically feasible. Robotic surgery is an attractive mode in performing minimally-invasive surgery once it has several advantages if compared to standard laparoscopic surgery. The aim of this paper is to report the first known case of colorectal resection surgery using the robotic assisted surgical device in Brazil. A 35-year-old woman with deep infiltrating endometriosis with rectal involvement was referred for colorectal resection using da Vinci® surgical system. The authors also reviewed the most current series and discussed not only the safety and feasibility but also the real benefits of robotic colorectal surgery


2009 ◽  
Vol 152 (2) ◽  
pp. 288-295 ◽  
Author(s):  
Anne Karliczek ◽  
David A. Benaron ◽  
Clark J. Zeebregts ◽  
Theo Wiggers ◽  
Gooitzen M. van Dam

2008 ◽  
Vol 199 (6) ◽  
pp. 636.e1-636.e4 ◽  
Author(s):  
Rubén A. Quintero ◽  
Ramen H. Chmait ◽  
Jane Carver ◽  
Patricia W. Bornick ◽  
Mary H. Allen ◽  
...  

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