First Subungual Cryptococcosis Described in an HIV Patient with Disseminated Cryptococcosis

2021 ◽  
pp. 1-3
Author(s):  
Soumiya Chiheb ◽  
Yasmine Slimani ◽  
Rajaa Karam ◽  
Farida Marnissi ◽  
Fouzia Hali
Keyword(s):  
Case Report ◽  
Systemic Therapy ◽  
Surgical Excision ◽  
Excisional Biopsy ◽  
Middle Finger ◽  
Yeast Cells ◽  
Histopathological Analysis ◽  
Cryptococcal Infection ◽  
The Right ◽  
Cutaneous Cryptococcosis

<b><i>Background:</i></b> Cutaneous cryptococcosis occurs in 10–15% of patients with disseminated cryptococcosis. It typically presents as papulonodular molluscum-like lesions, but it can also produce a wide variety of lesions. Cryptococcal infection of the nail unit has never been reported. <b><i>Case Report:</i></b> A 28-year-old woman with a history of HIV with disseminated cryptococcosis in complete remission was referred to evaluate a subungual swelling of the right middle finger. Examination revealed an ulcero-burgeoning nodule over the right middle finger’s subungual area with onycholysis, eschar, and erosion. An excisional biopsy was performed. Histopathological analysis demonstrated multiple histiocytic granulomas centered by encapsulated yeast cells. Culture grew <i>Cryptococcus neoformans var. neoformans</i>. After 9 months of follow-up, there was no recurrence of the lesion. <b><i>Discussion:</i></b> It is the first reported case of nail involvement in the course of cutaneous cryptococcosis. Definitive diagnosis required pathology and culture. Cryptococcal infection of the nail unit was recalcitrant to systemic therapy while the remaining infection cleared. Our case report suggests that surgical excision associated with systemic therapy is the best treatment approach for subungual cryptococcosis. Recognition of rare manifestations of cutaneous cryptococcosis, such as ours, is essential because HIV cases increase continuously.

scholarly journals 999 Case Report: A Rare Congenital Granular Cell Epulis In a Newborn Female Infant

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
R O'Rorke ◽  
D Ramkumar ◽  
S Jones
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Infant Feeding ◽  
Benign Lesion ◽  
Granular Cell ◽  
Surgical Excision ◽  
Excisional Biopsy ◽  
Histopathological Analysis ◽  
Anterior Maxilla ◽  
Congenital Granular Cell Epulis

Abstract Background A congenital granular cell epulis (CGCE) is a rare benign lesion of uncertain histologic origin that is found on the mucosa of the alveolar ridges of newborn babies. There have been less than 250 reported cases of CGCE. They are most commonly found in the anterior maxilla region in female infants. Case Report An 8-week-old female was referred from the Neonatal team with a 10mmX5mm lesion found at birth on the mucosa of the anterior maxilla. She was seen in the Oral and Maxillofacial Department where her parents reported that the lesion was causing discomfort when feeding and they were keen for its removal. On initial medical examination the patient was diagnosed with a Grade 1 ejection systolic murmur and was awaiting further cardiac investigations. With this in mind and the young age of the patient, it was decided an excisional biopsy of the lesion under local anaesthesia (LA) would be the safest option. The lesion was excised uneventfully when the patient was 9 weeks old. It was shown to be a congenital granular cell epulis following histopathological analysis. The patient was reviewed 8 weeks post-operatively. There were no signs of recurrence, the infant’s feeding had improved drastically, and she was thriving. Discussion CGCE is a rare and interesting lesion in neonates. Early diagnosis and treatment of CGCE is essential in facilitating infant feeding. This report highlights that a well-planned surgical excision under LA is a well-tolerated and safer option which is welcomed by parents.

scholarly journals A case report and literature review: post-traumatic mammary myofibroblastoma

2019 ◽  
Vol 6 (4) ◽  
pp. 1385 ◽  
Author(s):  
Hadi Abdullah Alaskar ◽  
Ahmed Mohammed AlMuhsin ◽  
Mirza Faraz Saeed ◽  
Amro Salem
Keyword(s):  
Case Report ◽  
Malignant Tumors ◽  
Surgical Excision ◽  
Excisional Biopsy ◽  
Clinical Findings ◽  
Histopathological Analysis ◽  
Minor Trauma ◽  
Elderly Age ◽  
Rare Benign Tumor ◽  
A Minor

Mammary myofibroblastoma is a rare benign tumor of the breast, with a higher incidence in elderly age group. It is diagnosed via radiologic and histologic findings, as clinical findings share the same presentation with other, more common, benign breast pathologies. Surgical excision is the only treatment modality used to treat this tumor. We report the case of a 56-years-old-male, who presented with the complaint of left-sided chest swelling for 1 year following a minor trauma to the chest. Ultrasonographic imaging of the mass was the initial investigation and it revealed a well-defined hypoechoic lesion, excisional biopsy was done, followed by histopathological analysis of the mass, which gave the diagnosis of mammary myofibroblastoma. The aim of this case-report is to further study and characterize this rare lesion and its relationship to previous minor or major trauma and other risk factors, in addition, a proper diagnosis should be taken when encountering a similar mass as it mimics many benign and malignant tumors, furthermore a follow up plan should be established to assess the rate of possible recurrence.

scholarly journals Extrauterine adenomyoma located in the inguinal region: a case report of a 44-year-old woman

2020 ◽  
Vol 2020 (10) ◽  
Author(s):  
Winesh Ramphal ◽  
Chloé M L Peters ◽  
Luthy S M Alcalá ◽  
Dennis van Hamont ◽  
Paul D Gobardhan
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Preoperative Diagnosis ◽  
Laparoscopic Hysterectomy ◽  
Surgical Excision ◽  
Inguinal Region ◽  
Histopathological Analysis ◽  
Pathologic Examination ◽  
Benign Tumours ◽  
The Right

Abstract Adenomyomas are benign tumours made of smooth muscle cells, endometrial glands and stroma. An extrauterine location is extremely rare with an unknown pathogenesis. Preoperative diagnosis is challenging and pathologic examination is necessary to confirm the diagnosis. Here we present a case report of a 44-year-old woman with a painful non-reducible mass in the right inguinal region without fever or other alarming symptoms 2 months after a laparoscopic hysterectomy. She was treated with a surgical resection of the mass. Extrauterine adenomyoma is a very uncommon entity. Preoperative workup is challenging, as confirmation of the diagnosis can only be achieved by histopathological analysis following surgical excision.

scholarly journals Intrascrotal lipoblastoma in adulthood

2019 ◽  
Vol 12 (12) ◽  
pp. e231320
Author(s):  
Mário José Pereira-Lourenço ◽  
Duarte Vieira-Brito ◽  
João Pedro Peralta ◽  
Noémia Castelo-Branco
Keyword(s):  
Case Report ◽  
Magnetic Resonance ◽  
S100 Protein ◽  
Surgical Excision ◽  
Large Mass ◽  
Histological Diagnosis ◽  
Physical Exam ◽  
Nodular Lesion ◽  
Inferior Portion ◽  
The Right

This case report describes the case of a 37-year-old man that noticed an intrascrotal right mass with 1 month of evolution. During physical exam presented with a large mass at the inferior portion of the right testicle, clearly separated from the testicle, with a tender consistency and mobile. An ultrasound was performed that showed a solid and subcutaneous nodular lesion, extra testicular, heterogeneous, measuring 7.2 cm. Pelvic magnetic resonance imageMRI showed a lesion compatible with a lipoma. The patient was subjected to surgical excision of the lesion by scrotal access, having histology revealed a lipoblastoma (LB) of the scrotum. Histological diagnosis was obtained by microscopic characteristics (well-circumscribed fatty neoplasm) and immunohistochemistry (stains for CD34, S100 protein and PLAG1 were positive; stains for MDM2 and CDK4 were negative). LB is extremely rare after adolescence in any location, being this first described case of intrascrotal LB described in adulthood.

scholarly journals Squamous Cell Carcinoma Arising at a Skin Graft Donor Site: Case Report and Review of the Literature

2021 ◽  
Vol 7 ◽  
pp. 2513826X2110084
Author(s):  
Weston Thomas ◽  
Kevin Rezzadeh ◽  
Kristie Rossi ◽  
Ajul Shah
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Skin Graft ◽  
Donor Site ◽  
Skin Grafting ◽  
Excisional Biopsy ◽  
Graft Donor ◽  
The Right

Introduction: Skin graft reconstruction is a common method of providing wound coverage. Rarely, skin grafting can be associated with the development of squamous cell carcinoma (SCC) in the graft donor site. Case Report: The patient is a 72-year old male with a 15-year history of bilateral hip wounds. He underwent a multitude of treatments previously with failed reconstructive efforts. After presenting to us, he underwent multiple debridements and eventual skin grafting. Within 4 weeks of the final skin graft, a mass developed at the skin graft donor site at the right thigh. Excisional biopsy returned a well differentiated keratinizing SCC. Discussion/Conclusion: This case demonstrates the acute presentation of SCC in a patient following a skin graft without known risk factors. The purpose of this unique case report is to highlight a very rare occurrence of SCC at a skin graft donor site.

scholarly journals Neuroendocrine Neoplasm in Cecal Appendix: A Case Report

2019 ◽  
Vol 4 (7) ◽  
pp. 118-126
Author(s):  
Pedro Walisson Gomes Feitosa ◽  
Andrezza Lobo Rodrigues ◽  
Esther Barbosa Gonçalves Felix ◽  
Maria Stella Batista de Freitas Neta ◽  
Sávio Samuel Feitosa Machado
Keyword(s):  
Case Report ◽  
Surgical Approach ◽  
Iliac Fossa ◽  
Neuroendocrine Neoplasm ◽  
Neuroendocrine Neoplasms ◽  
Histopathological Analysis ◽  
High Mitotic Activity ◽  
Precise Diagnosis ◽  
The Right ◽  
A Site

Although neuroendocrine neoplasms are relatively uncommon entities, the appendix is a site with relatively frequent emergence of this pathology and its precise diagnosis and clinical management have been a challenge for practitioners. This paper aims to present and discuss a case report of neuroendocrine neoplasia in the appendix of a patient with acute abdomen who underwent appendectomy. A 46-year-old man referred to the Emergency Department complaining of abdominal pain in the right iliac fossa and signs of peritoneal irritation. After diagnosis of acute appendicitis, the patient underwent appendectomy. In a macroscopic analysis, an area of 1.9 cm long, hardened, irregular and yellowish shapes was noted in the distal third of the appendix. Histopathological analysis showed neoplasia consisting of invasive islands of monotonous rounded epithelioid cells, large areas of necrosis, high mitotic activity, neural and angiolymphatic invasion and extension to adipose tissue compatible with invasion of the mesoappendix. Circumferential resection was compromised, suggesting the persistence of neoplasia in the patient even after the surgical approach, which would probably recommend the need for surgical approach. Therefore, the importance of sending collected materials for anatomopathological analysis is emphasized, since it helps in the clinical evaluation, in the etiological diagnosis, guides the medical conduct in the evolution of the case, as well as assisting in family mourning in cases of mortality.Keywords: Neuroendocrine tumor, Appendix, Histopathological analysis. 

scholarly journals Huge true aneurysm of the facial artery treated with internal trapping and surgical excision: a case report

2020 ◽  
Vol 2020 (9) ◽  
Author(s):  
Kiyoko Nakagawa ◽  
Takuji Yasuda ◽  
Natsuko Kobayashi ◽  
Kazuhiko Urabe
Keyword(s):  
Case Report ◽  
Case Reports ◽  
Surgical Excision ◽  
Facial Artery ◽  
True Aneurysm ◽  
The Right

Abstract A report of true aneurysms is extremely rare. There are only five previous case reports of true aneurysm of the facial artery. In the previously reported cases, there was no case that underwent trapping and surgical excision. In this case report, we describe the procedure of internal trapping before the surgical excision of a huge true aneurysm of the right facial artery for a 79-year-old woman. There was no recurrence of the aneurysm during a 6-month follow-up period.

scholarly journals Osteoid Osteoma of the Maxilla Presenting as Dental Implant Pain

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
R. Al Sadhan ◽  
A. Alosaimi ◽  
R. Al Shagroud ◽  
M. U. Zaman ◽  
M. S. Allahyani
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Osteoid Osteoma ◽  
Surgical Excision ◽  
Excisional Biopsy ◽  
Complete Relief ◽  
Radiographic Assessment ◽  
Solitary Lesion ◽  
The Right

Osteoid osteoma (OO) is a benign osteogenic lesion, regularly noticed in young individuals. A solitary lesion most frequently appears in long bones but is extremely rare in jawbones. Pain is a distinguishing characteristic of this lesion. Herein, we report a rare case of an OO in the right maxilla of a 37-year-old male presenting as pain associated with dental implants. Clinical and radiographic features were indicative of a benign neoplasia of boney origin. An excisional biopsy and histological examination of the lesion confirmed the diagnosis of osteoid osteoma. Surgical excision was followed by immediate relief of most of the pain. His follow-up visits were documented; complete relief of symptoms with no complications was observed during the postoperative period. There was no evidence of recurrence at a two-year follow-up. Osteoid osteoma of the maxilla may present as pain related to dental implants, and careful radiographic assessment of the entire jawbone should be considered if diagnosis of dental implant pain is unclear.

scholarly journals Vallecular cyst in an infant with stridor: a case report

2018 ◽  
Vol 6 (1) ◽  
pp. 58-62
Author(s):  
Nabin Lageju ◽  
Rajendra Prasad Sharma Guragain
Keyword(s):  
Case Report ◽  
Ct Scan ◽  
Cystic Lesion ◽  
Failure To Thrive ◽  
Surgical Excision ◽  
Infants And Children ◽  
Solid Component ◽  
Feeding Difficulties ◽  
The Right ◽  
In Infants And Children

Background and Objectives: Vallecular cysts are rare and generally asymptomatic. In infants and children they present with stridor, feeding difficulties, failure to thrive. Treatment is surgical excision with cautery or laser.Presentation of Case: We discuss the clinical, radiological presentation of a 7 months old child with vallecular cyst which was surgically treated with deroofing and marsupialisation with elecrocautery. There was no recurrence even up 2 years of follow-up.Discussion: Flexible nasopharyngolaryngoscopic examination was done which showed present of swelling in the left vallecula pushing the epiglottis posteriorly and to the right with narrowed normal endolarynx. Radiological investigations with CT scan showed cystic lesion noted in left side of neck with no septation and solid component. The lesion was extending to ipsilateral vallecula and paraglottic region with narrowing of endolarynx.Conclusion: Vallecular cyst is rare cause of noisy breathing in infants and children. In adults it is usually asymptomatic. Treatment of choice is marsupialization with electrocautery or laser.

scholarly journals A maxillary ameloblastic fibrosarcoma tumor: a rare case report from Syria

2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
Amjad Soltany ◽  
Ghazal Asaad ◽  
Rami Daher ◽  
Mouhannad Dayoub ◽  
Ali Khalil ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Rare Case ◽  
Soft Tissue Sarcomas ◽  
Surgical Excision ◽  
Low Grade ◽  
Rare Case Report ◽  
Ameloblastic Fibrosarcoma ◽  
The Right

Abstract Ameloblastic fibrosarcoma (AFS) is a rare, aggressive malignant odontogenic tumor. AFS is seen most frequently in second and third decades of life. We are reporting a case of a low grade AFS in a 21-year-old male complaining of a painless swelling in the right side of the maxilla. The patient was treated with surgical excision followed by radiotherapy, which is considered the most effective approach for most of soft tissue sarcomas. AFS has a high-reported recurrence rate (up to 37%); therefore, long-term surveillance for recurrence is crucial.

Sign in / Sign up

Export Citation Format

Share Document