scholarly journals Toxic Keratoconjunctivitis from Coral Reef

2021 ◽  
pp. 694-698
Author(s):  
Tedi Begaj ◽  
Stephan Ong Tone ◽  
Joseph B. Ciolino
Keyword(s):  
Coral Reef ◽  
Conjunctival Injection ◽  
Clinical Resolution ◽  
Topical Antibiotics ◽  
Fluid Content ◽  
Mild Disease ◽  
Eye Pain ◽  
Topical Corticosteroids ◽  
Close Observation ◽  
Corneal Infiltrates

A 25-year-old woman presented with right eye pain, lid edema, conjunctival injection and chemosis, and mild corneal epitheliopathy after exposure to fluid content from an aquarium coral reef. Topical moxifloxacin and prednisolone were started 4 times daily, with full clinical resolution after 2 weeks. Toxin-mediated keratoconjunctivitis may occur after exposure to zoanthid coral reef, particularly in aquarium enthusiasts. Topical corticosteroids in tandem with topical antibiotics appear to be effective in mild disease. However, in severe cases that exhibit corneal infiltrates and stromal thinning, close observation is warranted in case of possible keratolysis.

scholarly journals Simultaneous Subconjunctival Triamcinolone and Bevacizumab Injections for Management of Blepharokeratoconjunctivitis in Children

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Chu Luan Nguyen ◽  
Tony S. Chen ◽  
Khoi Tran ◽  
James E. H. Smith ◽  
Noni Lewis
Keyword(s):  
Conventional Treatment ◽  
Case Series ◽  
Corneal Neovascularization ◽  
Conjunctival Injection ◽  
Management Options ◽  
Conventional Management ◽  
Palpebral Conjunctiva ◽  
Meibomian Glands ◽  
Corneal Infiltrates ◽  
Red Eyes

Purpose. To report the efficacy of subconjunctival triamcinolone (Kenalog A-40, Alcon) and bevacizumab (Avastin, Genentech) injections in fraternal twins with blepharokeratoconjunctivitis (BKC) causing progressive, bilateral corneal neovascularization and scarring. Methods. In this retrospective observational case series, two three-year-old male twins with BKC had presented with bilateral red eyes, photophobia, and frequent blinking. Examination of each child showed bilateral deep stromal and superficial corneal neovascularization, corneal infiltrates, multiple follicles on the palpebral conjunctiva bilaterally with blepharitis, and thick turbid sebum expressed from the Meibomian glands. Their disease progressed despite conventional treatment. Both twins were managed with subconjunctival triamcinolone injection and subconjunctival bevacizumab injection of each eye. Results. The treatment resulted in improvement of symptoms, and examination over an 8-10-month period postinjections showed fading stromal corneal infiltrates, partially regressed corneal neovascularization, and reduced conjunctival injection without complications. Conclusion. This case series highlights the potential vision threatening complications of BKC. In addition to conventional management options, this report is the first published use of subconjunctival triamcinolone and bevacizumab injections for BKC in children in an attempt to minimize and improve corneal neovascularization and scarring and subsequently to retain useful vision.

Successful outpatient treatment of sinusitis exacerbations caused by community-acquired methicillin-resistant Staphylococcus aureus

2005 ◽  
Vol 132 (6) ◽  
pp. 828-833 ◽  
Author(s):  
Roland Z. Gerencer
Keyword(s):  
Outpatient Treatment ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Outpatient Basis ◽  
Oral Antibiotics ◽  
Clinical Resolution ◽  
Topical Antibiotics ◽  
Intravenous Antibiotics ◽  
The Mean ◽  
Mean Time

OBJECTIVE: To determine whether community-acquired MRSA sinusitis can be adequately treated on an outpatient basis without the need for intravenous antibiotics. STUDY DESIGN AND SETTING: Retrospective review of all cases of community-acquired MRSA sinusitis encountered by the author over a 36-month period. RESULTS: Of 29 patients who tested positive for MRSA sinusitis, 26 patients had follow-up information available and were retrospectively reviewed. The average follow-up period was 12.0 months (range: 1–36 mo). Twelve infectious episodes of MRSA were treated with oral antibiotics alone and 16 were treated with a combination of oral and topical antibiotics. The mean time to clinical resolution with these regimens was 5.7 weeks (range: 3–8 wks). Two patients experienced recurrent MRSA infections resulting in a recurrence rate of 7.7% and an overall resolution rate of 92.3%. CONCLUSIONS: Community-acquired MRSA sinusitis can be very adequately treated on an outpatient basis with culture-directed oral and topical antibiotics.

Hypersensitivity to topical corticosteroids in otitis externa

1993 ◽  
Vol 107 (7) ◽  
pp. 597-599 ◽  
Author(s):  
S. M. Wilkinson ◽  
M. H. Beck
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
External Auditory Canal ◽  
Otitis Externa ◽  
Topical Antibiotics ◽  
Topical Corticosteroids ◽  
Inflammatory Dermatosis ◽  
Allergic Contact

Over a12-monthperiod, nine patients were seen in a contact dermatitis clinic with an inflammatory dermatosis localized predominantly to the external auditory canal. Of these patients, four were found to have an allergic contact dermatitis which was exacerbating their dermatitis. All were allergic to one or more corticosteroids and topical antibiotics used in the treatment of their dermatitis. We would suggest that hypersensitivity to topical corticosteroids and other medicaments be considered in patients with otitis externa which fails to respond to treatment.

Development of Botanical Based Topical Antibiotics

Planta Medica ◽  
2013 ◽  
Vol 79 (10) ◽  
Author(s):  
KP Manfredi ◽  
M Walter ◽  
C Pitzen
Keyword(s):  
Topical Antibiotics

Screening for haemorrhagic disorders in paediatric patients by means of a questionnaire

2009 ◽  
Vol 29 (S 01) ◽  
pp. S87-S89 ◽  
Author(s):  
I. Music ◽  
M. Novak ◽  
B. Acham-Roschitz ◽  
W. Muntean
Keyword(s):  
Predictive Value ◽  
Laboratory Diagnosis ◽  
Von Willebrand Disease ◽  
Control Group ◽  
Older Children ◽  
Mild Disease ◽  
History Of ◽  
Von Willebrand ◽  
Specific Symptoms ◽  
Infants And Young Children

SummaryAim: In children, screening for haemorrhagic disorders is further complicated by the fact that infants and young children with mild disease in many cases most likely will not have a significant history of easy bruising or bleeding making the efficacy of a questionnaire even more questionable. Patients, methods: We compared the questionnaires of a group of 88 children in whom a haemorrhagic disorder was ruled out by rigorous laboratory investigation to a group of 38 children with mild von Willebrand disease (VWD). Questionnaires about child, mother and father were obtained prior to the laboratory diagnosis on the occasion of routine preoperative screening. Results: 23/38 children with mild VWD showed at least one positive question in the questionnaire, while 21/88 without laboratory signs showed at least one positive question. There was a trend to more specific symptoms in older children. Three or more positive questions were found only in VWD patients, but only in a few of the control group. The question about menstrual bleeding in mothers did not differ significantly. Sensitivity of the questionnaire for a hemostatic disorder was 0.60, while specifity was 0.76. The negative predictive value was 0.82, but the positive predictive value was only 0.52. Conclusions: Our small study shows, that a questionnaire yields good results to exclude a haemostatic disorder, but is not a sensitive tool to identify such a disorder.

Movement and growth of the coral reef holothuroids Bohadschia argus and Thelenota ananas

2016 ◽  
Vol 551 ◽  
pp. 201-214 ◽  
Author(s):  
SW Purcell ◽  
TP Piddocke ◽  
SJ Dalton ◽  
YG Wang
Keyword(s):  
Coral Reef
Sign in / Sign up

Export Citation Format

Share Document