scholarly journals Predictors of Short- and Long-Term Mortality in Ischemic Stroke: A Community-Based Study in Brno, Czech Republic

2021 ◽  
pp. 1-8
Author(s):  
Tomas Bryndziar ◽  
Dominika Matyskova ◽  
Petra Sedova ◽  
Silvie Belaskova ◽  
Miroslav Zvolsky ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Czech Republic ◽  
Cardiac Failure ◽  
Mortality Rates ◽  
Nihss Score ◽  
History Of ◽  
Short And Long Term ◽  
Statin Use ◽  
Long Term Mortality

<b><i>Background and Objective:</i></b> Short- and long-term mortality following ischemic stroke (IS) and their predictors have not been defined in the Czech population, and studies on long-term mortality are largely missing for the populations of Central Europe. <b><i>Methods:</i></b> Using the National Register of Hospitalized Patients and the Czech National Mortality Registry, we analyzed data on 1-month, 1-year, and 3-year all-cause mortality for patients admitted with IS to any of the 4 hospitals with a certified stroke unit in Brno, Czech Republic, in 2011. We reviewed discharge summaries and recorded potential factors impacting mortality after the index stroke event. Using univariate and multivariable analyses, we identified predictors of mortality at all 3 time points. <b><i>Results:</i></b> In our multivariable model, statin use (odds ratio [OR] 0.095, <i>p</i> &#x3c; 0.0001), age at stroke (OR 1.03, <i>p</i> = 0.0445), and admission National Institutes of Health Stroke Scale (NIHSS) score (OR 1.16, <i>p</i> &#x3c; 0.0001) predicted 1-month mortality, while statin use (OR 0.43, <i>p</i> = 0.0004), history of cardiac failure (OR 2.17, <i>p</i> = 0.0137), age at stroke (OR 1.07, <i>p</i> &#x3c; 0.0001), and admission NIHSS score (OR 1.14, <i>p</i> &#x3c; 0.0001) predicted 1-year mortality. Statin use (OR 0.54, <i>p</i> = 0.0051), history of cardiac failure (OR 2.13, <i>p</i> = 0.0206), age at stroke (OR 1.07, <i>p</i> &#x3c; 0.0001), and admission NIHSS score (OR 1.11, <i>p</i> &#x3c; 0.0001) also predicted 3-year mortality. <b><i>Conclusions:</i></b> Our study is the first to report data on short- and long-term mortality rates and their predictors in patients hospitalized with IS in the Czech population. Our results indicate that mortality rates and predictors of mortality are consistent with those reported in studies from other populations throughout the world.

scholarly journals Epidemiology of Major Lower Extremity Amputations in Individuals With Diabetes in Austria, 2014-2017: A Retrospective Analysis of Health Insurance Database

2020 ◽  
Author(s):  
Faisal Aziz ◽  
Berthold Reichardt ◽  
Caren Sourij ◽  
Hans-Peter Dimai ◽  
Daniela Reichart ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Health Insurance ◽  
Lower Extremity ◽  
Renal Disease ◽  
Mortality Rates ◽  
Short And Long Term ◽  
Male Sex ◽  
Long Term Mortality

Abstract Background: Previous data show a high incidence of major lower extremity amputations (LEA) in Austria. Moreover, recent data on the epidemiology of major LEA are sparse in the Country. This study estimated the incidence and mortality rates of major LEA and assessed risk factors of post major LEA mortality in individuals with diabetes.Methods: A retrospective cohort analysis of 507,180 individuals with diabetes enrolled in the Austrian Health Insurance between 2014 and 2017 was performed. Crude and age-standardized rates of major LEA (hip, femur, knee, lower leg) were estimated by extracting their procedure codes from the database. Short- (30-day, 90-day) and long-term (1-year, 5-year) all-cause cumulative mortality after major LEA was estimated from the date of amputation till the date of death. Poisson regression was performed to compare rates by characteristics and assess the annual trend. The Cox-regression was performed to identify significant risk factors of all-cause mortality after major LEA.Results: A total of 2,165 individuals with diabetes underwent major LEA between 2014 and 2017. The mean age was amputees was 73.0 ±11.3 years, 62.7% were males, and 87.3% had a peripheral vascular disease (PVD). The overall age-standardized rate was 6.44 per 100,000 population. The rate increased with age (p<0.001) and was higher (p<0.001) in males (9.38) than females (5.66). The rate was 5.71 in 2014, 6.86 in 2015, 6.71 in 2016, and 6.66 in 2017, with an insignificant annual change of 3% (p=0.825). The cumulative 30-day mortality was 13.5%, 90-day was 22.0%, 1-year was 34.4%, and 5-year was 66.7%. Age, male sex, above-knee amputation, Charlson index, and heart failure were significantly associated with both short- and long-term mortality. Cancer, dementia, heart failure, PVD, and renal disease were only associated with long-term mortality.Conclusions: The rate of major LEA remained stable between 2014 and 2017 in Austria. Short and long-term mortality rates were considerably high after major LEA. Old age, male sex, above-knee amputations, heart failure, and Charlson Index were significant predictors of both short- and long-term mortality, whereas, comorbidities such as cancer, dementia, PVD, and renal disease were significant predictors of long-term mortality only.

Abstract WP514: Association Between Statin Utilization and Short- and Long-term Mortality Among Patients With TIA and Ischemic Stroke

Stroke ◽  
2019 ◽  
Vol 50 (Suppl_1) ◽  
Author(s):  
Jason Sico ◽  
Xin Hu ◽  
Susan Ofner ◽  
Fitsum Baye ◽  
Jennifer Dearborn ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Short And Long Term ◽  
Long Term Mortality

Predicting short and long-term mortality after acute ischemic stroke using EHR

2021 ◽  
pp. 117560
Author(s):  
Vida Abedi ◽  
Venkatesh Avula ◽  
Seyed-Mostafa Razavi ◽  
Bavishi Shreya ◽  
Durgesh Chaudhary ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Short And Long Term ◽  
Long Term Mortality

Impact of Pulmonary Artery Catheter Use on Short- and Long-Term Mortality in Patients with Cardiogenic Shock

Cardiology ◽  
2016 ◽  
Vol 136 (1) ◽  
pp. 61-69 ◽  
Author(s):  
Xavier Rossello ◽  
Montserrat Vila ◽  
Mercedes Rivas-Lasarte ◽  
Andreu Ferrero-Gregori ◽  
Jordi Sans-Roselló ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Cardiogenic Shock ◽  
Mortality Rates ◽  
Coronary Syndrome ◽  
Short Term Mortality ◽  
Long Term Follow Up ◽  
Short And Long Term ◽  
The Impact ◽  
Long Term Mortality

Objectives: The impact of pulmonary artery catheterization (PAC) on survival in patients with cardiogenic shock (CS) is not well established. This study aimed to assess whether Swan-Ganz catheter monitoring is related to short- and long-term mortality in patients with CS. Methods: One hundred and twenty-nine consecutive patients with a first admission for CS were prospectively enrolled in a single-center registry between December 2005 and May 2009, and were subsequently followed up over 5.3 years. Results: PAC was used in 64% of all patients with a mean age of 68 years (65% men). After adjustment for age, gender and the presence of CS upon admission, PAC was associated with lower short-term mortality [hazard ratio (HR) = 0.55, 95% confidence interval (CI) 0.35-0.86, p = 0.008] as well as lower mortality rates in the long-term follow-up (HR = 0.63, 95% CI 0.41-0.97, p = 0.035). In a subgroup analysis, the use of PAC was associated with reduced mortality in patients without acute coronary syndrome (ACS), i.e. 49% in the Swan-Ganz group vs. 82% (p = 0.010), but there was no difference within the ACS group. Conclusions: The use of PAC in patients with CS was associated with lower short- and long-term mortality rates after adjustment for age, gender and the presence of shock upon admission. This benefit was only significant in those patients without ACS.

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