scholarly journals Patients with Hidradenitis Suppurativa Suffer from Low Health-Related Quality of Life as Measured by the Generic 15D Instrument

2021 ◽  
pp. 1-7
Author(s):  
Mirkka J. Hirvonen ◽  
Rafael Pasternack ◽  
Tiina Lipitsä ◽  
Armi Vihervaara ◽  
Rauno Harvima ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Disease Severity ◽  
Hidradenitis Suppurativa ◽  
Clinical Severity ◽  
Dimensional Measure ◽  
Measurement Tools ◽  
Health Related Qol ◽  
Related Quality ◽  
Health Related

<b><i>Introduction:</i></b> Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease associated with various comorbidities and diminished quality of life (QoL). Among dermatological conditions, HS is reported to most severely diminish QoL. This study aimed to analyse the health-related QoL (HRQoL) of patients with HS in more detail by using generic to disease-specific HRQoL questionnaires. Correlations between the HRQoL measures and HS disease severity measures were assessed. <b><i>Methods:</i></b> We analysed the HRQoL and clinical severity of patients with HS (<i>N</i> = 92) treated in 5 Finnish hospitals using HRQoL measurement tools most often used in dermatological clinics, as well as the generic 15D instrument (standardized and self-administered 15-dimensional measure of HRQoL). The disease severity was assessed using the Hurley stage, International Hidradenitis Suppurativa Severity Score System, and disease severity evaluation by the investigator. <b><i>Results:</i></b> The mean 15D score of HS patients was low and comparable with that of patients with cancers. No correlation was found between HS severity measures and 15D score, indicating that even mild HS has a high impact on HRQoL. <b><i>Conclusions:</i></b> Our findings strengthen the understanding about HS as a debilitating disease and even compared with non-dermatological conditions and highlight the need of comprehensive care of patients with HS.

scholarly journals Quality of Life in Hidradenitis Suppurativa: An Update

2021 ◽  
Vol 18 (11) ◽  
pp. 6131
Author(s):  
Pavel V. Chernyshov ◽  
Andrew Y. Finlay ◽  
Lucia Tomas-Aragones ◽  
Francoise Poot ◽  
Francesca Sampogna ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hidradenitis Suppurativa ◽  
Acne Inversa ◽  
Health Related Quality ◽  
Number Of Patients ◽  
Related Quality ◽  
Health Related ◽  
Positive Effect ◽  
Specific Health

Knowledge on hidradenitis suppurativa/acne inversa (HS) is rapidly increasing. HS has a profound impact on patients and their family life. Several factors, such as comorbidities, unemployment and HS severity, make this impact even more severe. The most widely used instrument to measure this impact is the dermatology-specific DLQI. We also identified six HS-specific health-related quality of life (HRQoL) instruments. Of them, HIDRAdisk, HSIA, HiSQOL and HSQoL-24 are better validated but there is still lack of experience of its use. Several treatment methods showed positive effect on patients’ HRQoL. Surgery remains a method with a substantial positive effect on HRQoL. Several studies confirming a positive effect of adalimumab on the HRQoL of patients with HS were published during the last three years. Data on the influence of several other biologics on HRQoL of HS patients are controversial or based on studies with a small number of patients.

A Comparison of the Level of Dyspnea vs Disease Severity in Indicating the Health-Related Quality of Life of Patients With COPD

CHEST Journal ◽  
1999 ◽  
Vol 116 (6) ◽  
pp. 1632-1637 ◽  
Author(s):  
Takashi Hajiro ◽  
Koichi Nishimura ◽  
Mitsuhiro Tsukino ◽  
Akihiko Ikeda ◽  
Toru Oga ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Disease Severity ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Quality of Life and Health for Patients with Chronic Periodontitis: A Qualitative Study

2020 ◽  
Author(s):  
Jeehee Pyo ◽  
Ji-Hyun Lee ◽  
Mina Lee ◽  
Minsu Ock
Keyword(s):  
Quality Of Life ◽  
Periodontal Disease ◽  
Dental Care ◽  
Dental Health ◽  
The Elderly ◽  
Health Related Quality ◽  
Health Related Qol ◽  
Related Quality ◽  
Health Related

Abstract Background: Disease burden created by periodontal disease has been recognized as a global challenge. The burden of medical expenses is expected to increase continuously, parallel to the growth of the elderly population. Periodontal disease causes tooth loss if not treated early, and advanced periodontitis can cause a decline in chewing ability and word pronunciation as well as aesthetic function. These results diminish the health-related quality of life (QOL) for various populations, particularly the elderly, adults, pregnant women, and workers. Thus, not only is early detection and management of the disease necessary, but also a systematic strategy for the prevention of periodontal diseaseMethods: Adults 19 years of age or older diagnosed with chronic gingivitis (K05.1) or chronic periodontitis (K05.3) under the ICD-10 codes were selected to participate in the study. Among the patients visiting the dental outpatient department, the study participants were chosen for our sample. A total of 20 participants were informed of the purpose of the study and gave consent to participate in in-depth interviews.Results: The analysis results were summarized into the four upper categories of ‘Interfering Element for Dental Care,’ ‘Declined Quality of Life caused by Dental Disease,’ ‘Satisfaction Elements after Treatment of Dental Disease,’ ‘Improvements for Voluntary Dental Care.’ The treatment of periodontal disease has improved the health-related quality of life and enabled the participants to have positive health behaviors for dental care. Furthermore, they recognized the severity of periodontal disease and the importance of dental examinations. It enabled them to be aware of the need of societal effort for dental care awareness.Conclusions: This study was an in-depth examination of the health-related QOL of periodontal patients through qualitative research methodology. The experiences of periodontal disease identified by this study can not only help to assess the adequacy of the current dental health-related QOL assessment tools but also recognize unmet needs regarding periodontal disease and, ultimately, to raise the awareness of periodontal disease among the general public. Based on this research, we expect that research on health-related QOL on periodontal disease would expand and revitalize the dental health system and practices.

scholarly journals Effects of Euglena gracilis EOD-1 Ingestion on Salivary IgA Reactivity and Health-Related Quality of Life in Humans

Nutrients ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 1144 ◽  
Author(s):  
Ken-ichi Ishibashi ◽  
Machiko Nishioka ◽  
Nobuteru Onaka ◽  
Madoka Takahashi ◽  
Daisuke Yamanaka ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Euglena Gracilis ◽  
Health Related Quality ◽  
Salivary Iga ◽  
Health Related Qol ◽  
Related Quality ◽  
Health Related ◽  
Antibody Titers ◽  
Iga Antibody

Euglena gracilis EOD-1, a microalgal strain known for high yields of the β-1, 3-glucan paramylon, is suggested to function as a dietary fiber and enhance immunity. Here, we aimed to investigate the effects of E. gracilis EOD-1 biomass (EOD1BM) ingestion on immunoglobulin A (IgA) antibody titers in saliva, its reactivity, and the health-related quality of life (QOL) in humans. Reacting human immunoglobulin preparations and saliva with paramylon granules revealed the presence of anti-paramylon antibodies in the blood and saliva. We conducted a placebo-controlled, double-blind, crossover study involving 13 healthy subjects who ingested the placebo or EOD1BM for 4 weeks. Saliva was collected from each subject before and after ingestion, and IgA titers and E. gracilis EOD-1 paramylon (EOD1PM) reactivity were compared. In the EOD1BM Ingestion group, the anti-EOD1PM IgA content and titer increased after EOD1BM ingestion. No such change was observed in the Placebo group. Furthermore, the health-related QOL, especially mental health, increased in the EOD1BM Ingestion group. Thus, EOD1BM ingestion led to the production of paramylon (PM)-specific IgA antibody and increased salivary IgA antibody titers. We demonstrate that EOD1BM ingestion enhanced the immunity in the mucosal surface, evoked an antigen-specific response, and increased the health-related QOL, thereby contributing to health improvement.

scholarly journals Association between Clinical Signs of Oral Lichen Planus and Oral Health-Related Quality of Life: A Preliminary Study

2020 ◽  
Vol 8 (4) ◽  
pp. 113
Author(s):  
Sasirin Yiemstan ◽  
Sudaduang Krisdapong ◽  
Pornpan Piboonratanakit
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Oral Lichen Planus ◽  
Clinical Severity ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Oral Lichen ◽  
Oral Impacts

Subjective patient’s symptoms and Oral Health-Related Quality of Life (OHRQoL) are recommended to be involved in oral lichen planus (OLP) studies. This study aims to assess the OHRQoL of OLP patients, and their associations with pain and OLP in Thai patients. Sixty-nine patients were interviewed using the Numeric Rating Scale (NRS) for pain perception and Oral Impacts on Daily Performance (OIDP) index. OLP signs examined included localization, types, number of affected sides and clinical severity using the Thongprasom sign scoring system. There were significant associations (rs = 0.490, p < 0.001) between clinical severity and the intensity of oral impacts as well as pain (rs = 0.298, p = 0.013). The intensity of oral impacts and pain increased according to the increasing OLP clinical severity, except for the white striae lesions (Thongprasom sign score 1). The erosive/ulcerative OLP lesions (Thongprasom sign scores 4 and 5) were the most painful symptom and had the highest degree of oral impacts (p < 0.001). No significant associations were found between the number of affected lesion sides and OHRQoL (p = 0.316) and pain (p = 0.284). OHRQoL was associated with OLP type and clinical severity but not with the number of affected sides.

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