scholarly journals Laser fluorescence as an alternative for digital radiography in detecting caries lesions

2020 ◽  
Author(s):  
Lucila Massu Yoshizaki Akinaga Moreira ◽  
Bruna Cordeiro Amarante ◽  
Bruno Munhoz Marotta ◽  
Christyan Hiroshi Iida ◽  
Danielle Ayumi Nishimura ◽  
...  
Keyword(s):  
Diagnostic Method ◽  
Near Infrared ◽  
New Technologies ◽  
Assessment System ◽  
Laser Fluorescence ◽  
Infrared Light ◽  
Caries Detection ◽  
Complementary Method ◽  
Diagnodent Pen ◽  
Caries Lesions

Diagnosis of caries lesions consists of visual/tactile methods following the International Caries Detection and Assessment System (ICDAS) and radiographic methods (BW), however these methods have limitations for detecting caries at different depths and locations and is usually influenced by the examiner’s experience. New technologies have emerged to improve caries diagnosis methods, among these are methods that use optical principles to quantify differences between healthy and demineralized tissues, for example: quantitative light- -induced fluorescence (QLF), the “DIAGNOdent” caries detection pen, and VistaProof (fluorescence camera). This literature review aims to provide up-to-date information on the applicability of fluorescence-based methods in the diagnosis of caries. The results show that DIAGNOdent pen was the most effective method for diagnosing caries, wherein some authors indicate that it can be used as the only diagnostic method, but most recommend using it as a complementary method to ICDAS and BW. LFpen must be used in association with ICDAS and 2 articles indicate near-infrared light transillumination (NILT) as a substitute for BW, however there is still a need for further studies to reach a concrete decision. In conclusion, digital methods for the diagnosis of caries are efficient, but they do not replace visual/tactile methods and bitewing radiographs. Therefore, they should be used as a complementary diagnostic method to those already known and widely used and studied.

scholarly journals Occlusal Caries Detection and Diagnosis Using Visual ICDAS Criteria, Laser Fluorescence Measurements, and Near-Infrared Light Transillumination Images

2019 ◽  
Vol 29 (1) ◽  
pp. 25-31 ◽  
Author(s):  
Melek Tassoker ◽  
Sevgi Ozcan ◽  
Said Karabekiroglu
Keyword(s):  
Near Infrared ◽  
Third Molar ◽  
Laser Fluorescence ◽  
Infrared Light ◽  
Caries Detection ◽  
Occlusal Caries ◽  
Fluorescence Measurements ◽  
Diagnodent Pen ◽  
Icdas Ii ◽  
Molar Teeth

Objective: Current diagnostic tools for non-cavitated occlusal caries are not very reliable. For this reason, newer systems need to be developed. The aim of this study was to compare the performance of visual inspection (ICDAS-II), laser fluorescence (DIAGNOdent pen), and the near-infrared transillumination technique (DIAGNOcam) in the detection of non-cavitated occlusal caries lesions under clinical and laboratory conditions in 90 third molar teeth planned for extraction. Materials and Methods:Ninety third molar teeth were firstly examined in clinical conditions, scored according to ICDAS-II criteria, and examined with DIAGNOdent pen and DIAGNOcam devices. After finishing the clinical examination, the teeth were re-evaluated shortly after the extractions with the same methods. Then, the teeth were sectioned for histological validation according to Downer’s criteria. Sensitivity, specificity, accuracy, and area under the receiver operating characteristic (ROC) curves were calculated based on the histological results. Results: For the D0–D1–4 threshold, the area under the ROC curve values ranged between 0.754 and 0.881 for all systems. Sensitivity values ranged between 80.5 and 96.1%, and specificity values ranged between 61.5 and 84.6% for the three caries detection methods. DIAGNOcam had the best correlation value (0.616) according to histological observations and demonstrated a sensitivity rate of 96.1%, a specificity rate of 61.5%, and an accuracy rate of 91.1%. Conclusions: DIAGNOcam was found to be the most effective method for the diagnosis of occlusal caries without cavitation in permanent molar teeth.

scholarly journals Comparison of Laser Fluorescence and Digital Radiograph with International Caries Detection and Assessment System in Primary Teeth (In-vivo study)

2021 ◽  
Vol 17 (14) ◽  
Author(s):  
Rana Kassab ◽  
Nayer Abo Elsaad ◽  
Shiern Badr
Keyword(s):  
Primary Teeth ◽  
Clinical Performance ◽  
Assessment System ◽  
Diagnostic Methods ◽  
Caries Detection ◽  
Occlusal Caries ◽  
Bitewing Radiography ◽  
Diagnodent Pen ◽  
Icdas Ii ◽  
Caries Lesions

Background: There has been an increased incidence of dental caries in children due to recent changes in lifestyle. More sensitive and reproducible diagnostic tools for precise caries detection in children are needed because of the complex occlusal anatomy. Aim: To compare the clinical performance and accuracy of international caries detection and assessment system-II (ICDAS II) versus DIAGNOdent pen and digital bitewing radiograph in the detection of occlusal caries in the primary teeth. Materials and Methods: Fifty children aged 6-11 years were assessed of both gender (29 girls and 21 boys) and 377 occlusal surface of primary teeth were examined by visual ICDAS II, DIAGNOdent pen and digital bitewing radiographic examination at D0 (non caries lesions), D1 (lesions limited to enamel) and D2 (lesions limited to dentin) thresholds. Results: Sensitivity at D0 for ICADS II was 14.23% and 95.95% for DIAGNOdent pen and 87.85% for digital bitewing, radiographs while specificity for both ICADS II and bitewing radiographs were 99.23% but 73.85% for DIAGNOdent pen. At D1, threshold sensitivity of ICADS II and digital bitewing radiographs were higher than DIAGNOdent pen but specificity for bitewing radiographs and DIAGNOdent pen 90.69% - 87.99%. were highly significant than ICADS II At D2, threshold specificity for all diagnostic methods was almost similar with better sensitivity for ICADS II and digital bitewing radiographs. Conclusion: This study showed that ICDAS II, Diagnodent pen, and bitewing radiography are effective for the detection of occlusal caries for primary molars. Digital bitewing radiography correlated stronger with ICDASII than Diagnodent pen and proved to be the best method to detect occlusal lesions within the dentin in primary molars while Diagnodent pen and bitewing radiography are better for detecting enamel caries lesion. In addition, the clinical performance of three diagnostic methods was insufficient to detect occlusal caries lesions separately. Consequently, it is advisable to use a combination of diagnostic methods, especially in unclear cases, as well as in cases of initial lesions and their monitoring.

scholarly journals Self-assembling Peptide P11-4 and Fluoride for Regenerating Enamel

2017 ◽  
Vol 97 (2) ◽  
pp. 148-154 ◽  
Author(s):  
M. Alkilzy ◽  
A. Tarabaih ◽  
R.M. Santamaria ◽  
C.H. Splieth
Keyword(s):  
Odds Ratio ◽  
Test Group ◽  
Assessment System ◽  
Laser Fluorescence ◽  
Fluoride Varnish ◽  
Caries Detection ◽  
Control Group ◽  
Analog Scale ◽  
Self Assembling ◽  
Carious Lesions

Regenerative medicine-based approaches for caries treatment focus on biomimetic remineralization of initial carious lesions as a minimal invasive therapy. In vitro, self-assembling peptide P11-4 enhances remineralization of early carious lesions. To investigate the safety and clinical efficacy of P11-4 for treatment of initial caries, a randomized controlled single-blind study was conducted on children aged >5 y with visible active early caries on erupting permanent molars. Subjects were randomized to either the test group (P11-4 + fluoride varnish) or control group (fluoride varnish alone). Caries were assessed at baseline and at 3 and 6 mo posttreatment per laser fluorescence, a visual analog scale, the International Caries Detection and Assessment System, and Nyvad caries activity criteria. Intention-to-treat analyses were performed, and safety and clinical feasibility of the treatment approaches were assessed. Compared with the control group, the test group showed clinically and statistically significant improvement in all outcomes at 3 and 6 mo. The laser fluorescence readings (odds ratio = 3.5, P = 0.015) and visual analog scale scores (odds ratio = 7.9, P < .0001) were significantly lower for the test group, and they showed regression in the International Caries Detection and Assessment System caries index (odds ratio = 5.1, P = 0.018) and conversion from active to inactive lesions according to Nyvad criteria (odds ratio = 12.2, P < 0.0001). No adverse events occurred. The biomimetic mineralization facilitated by P11-4 in combination with fluoride application is a simple, safe, and effective noninvasive treatment for early carious lesions that is superior to the presently used gold standard of fluoride alone. By regenerating enamel tissue and preventing lesion progression, this novel approach could change clinical dental practice from a restorative to a therapeutic approach. This could avoid additional loss of healthy hard tissue during invasive restorative treatments, potentially enabling longer tooth life and thereby lowering long-term health costs ( ClinicalTrials.gov NCT02724592).

scholarly journals Combined Near-Infrarred Light Transillumination and Direct Digital Radiography Increases Diagnostic In Approximal Caries

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Maria Melo ◽  
Agustin Pascual ◽  
Isabel Camps ◽  
Fadi Ata-Ali ◽  
Javier Ata-Ali
Keyword(s):  
Digital Radiography ◽  
Gold Standard ◽  
Near Infrared ◽  
Infrared Light ◽  
Caries Detection ◽  
Posterior Teeth ◽  
Lesion Extension ◽  
Diagnostic Capacity ◽  
Approximal Caries ◽  
Approximal Surface

Abstract The objective of this study was to evaluate the clinical ability of Near-Infrared Light-Transillumination (NILT) for approximal dentinal caries detection and to compare with direct digital-radiography (DDR), as well as to determine whether the combination of both techniques improves the diagnostic capacity of the lesions. From 88 patients (over 18 years), 138 posterior teeth (76 molars and 62 premolars), that had approximal caries reached into dentine determined by DDR, were included. Lesion extension and DDR images were scored as follows: D0 = sound surface, D1/D2 = caries restricted to the outer/inner-half of the enamel, and D3/4 = caries restricted to the outer/inner-half of the dentin. Opening of the approximal surface using 0.5 mm-in-diameter diamond-bar was used as gold-standard. The lesion extension was then determined by the following criteria: no dentinal caries (D0/1/2) or dentinal caries (D3/4). Seventy-one lesions were D3 and 67 lesions were D4. Sensitivities of overall/D3/D4 were 98.0/95.7/100.0 (NILT) and 100/100/100 (DDR), respectively. Correlations with gold-standard were 0.92 (NILT) and 0.42 (DDR), respectively. The correlation increased to 0.97 (p = 0.045) on combining NILT and DDR. There was no difference in sensitivity between the methods (p > 0.05); but was differences in the correlation (p < 0.01). It can be concluded that NILT showed sensitivity similar to that of DDR and higher correlation than DDR for approximal dentinal caries detection. Accordingly, it may be used to monitor the progression of caries without exposing the patient to ionizing radiation, this being of particular interest in growing patients and in pregnant women. In this respect, NILT can be an effective diagnostic tool adjunctive to bitewing radiographs in detecting approximal dentinal caries. The combination of NILT and DDR represents an increase in the diagnosis of approximal lesions The proposed diagnostic protocol comprises visual examination, followed by NILT and DDR only if the former technique detects approximal caries.

scholarly journals Metabolic Profile of Supragingival Plaque Exposed to Arginine and Fluoride

2019 ◽  
Vol 98 (11) ◽  
pp. 1245-1252 ◽  
Author(s):  
M.M. Nascimento ◽  
A.J. Alvarez ◽  
X. Huang ◽  
C. Browngardt ◽  
R. Jenkins ◽  
...  
Keyword(s):  
Acid Production ◽  
Metabolic Profile ◽  
Assessment System ◽  
Caries Detection ◽  
Metabolic Profiles ◽  
Ph Homeostasis ◽  
Supragingival Plaque ◽  
Plaque Ph ◽  
Oral Biofilms ◽  
Caries Lesions

Caries lesions develop when acid production from bacterial metabolism of dietary carbohydrates outweighs the various mechanisms that promote pH homeostasis, including bacterial alkali production. Therapies that provide arginine as a substrate for alkali production in supragingival oral biofilms have strong anticaries potential. The objective of this study was to investigate the metabolic profile of site-specific supragingival plaque in response to the use of arginine (Arg: 1.5% arginine, fluoride-free) or fluoride (F: 1,100 ppm F/NaF) toothpastes. Eighty-three adults of different caries status were recruited and assigned to treatment with Arg or F for 12 wk. Caries lesions were diagnosed using International Caries Detection and Assessment System II, and plaque samples were collected from caries-free and carious tooth surfaces. Taxonomic profiles were obtained by HOMINGS (Human Oral Microbe Identification using Next Generation Sequencing), and plaque metabolism was assessed by the levels of arginine catabolism via the arginine deiminase pathway (ADS), acidogenicity, and global metabolomics. Principal component analysis (PCA), partial least squares–discriminant analysis, analysis of variance, and random forest tests were used to distinguish metabolic profiles. Of the 509 active lesions diagnosed at baseline, 70 (14%) were inactive after 12 wk. Generalized linear model showed that enamel lesions were significantly more likely to become inactive compared to dentin lesions ( P < 0.0001), but no difference was found when treatment with Arg was compared to F ( P = 0.46). Arg significantly increased plaque ADS activity ( P = 0.031) and plaque pH values after incubation with glucose ( P = 0.001). F reduced plaque lactate production from endogenous sources ( P = 0.02). PCA revealed differences between the metabolic profiles of plaque treated with Arg or F. Arg significantly affected the concentrations of 16 metabolites, including phenethylamine, agmatine, and glucosamine-6-phosphate ( P < 0.05), while F affected the concentrations of 9 metabolites, including phenethylamine, N-methyl-glutamate, and agmatine ( P < 0.05). The anticaries mechanisms of action of arginine and fluoride are distinct. Arginine metabolism promotes biofilm pH homeostasis, whereas fluoride is thought to enhance resistance of tooth minerals to low pH and reduce acid production by supragingival oral biofilms.

scholarly journals In vivo performance of near-infrared light transillumination for dentine proximal caries detection in permanent teeth

2020 ◽  
Vol 32 (4) ◽  
pp. 187-193
Author(s):  
Ayşe Dündar ◽  
Mehmet Ertuğrul Çiftçi ◽  
Özlem İşman ◽  
Ali Murat Aktan
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Caries Detection ◽  
Permanent Teeth ◽  
Near Infrared Light ◽  
Proximal Caries

scholarly journals Monitoring of Sound and Carious Surfaces under Sealants over 44 Months

2014 ◽  
Vol 93 (11) ◽  
pp. 1070-1075 ◽  
Author(s):  
M. Fontana ◽  
J.A. Platt ◽  
G.J. Eckert ◽  
C. González-Cabezas ◽  
K. Yoder ◽  
...  
Keyword(s):  
Assessment System ◽  
Retention Rates ◽  
Caries Detection ◽  
Major Barrier ◽  
Occlusal Surfaces ◽  
Before And After ◽  
Permanent Molars ◽  
Caries Lesions ◽  
Sealant Retention ◽  
Lesion Severity

Although there is strong evidence for the effectiveness of sealants, one major barrier in sealant utilization is the concern of sealing over active caries lesions. This study evaluated detection and monitoring of caries lesions through a clear sealant over 44 mo. Sixty-four 7- to 10-year-old children with at least 2 permanent molars with International Caries Detection and Assessment System (ICDAS) scores 0-4 (and caries less than halfway through the dentin, radiographically) were examined with ICDAS, DIAGNOdent, and quantitative light-induced fluorescence (QLF) before sealant placement and 1, 12, 24, and 44 mo (except QLF) after. Bitewing radiographs were taken yearly. DIAGNOdent and QLF were able to distinguish between baseline ICDAS before and after sealant placement. There was no significant evidence of ICDAS progression at 12 mo, but there was small evidence of minor increases at 24 and 44 mo (14% and 14%, respectively) with only 2% ICDAS ≥ 5. Additionally, there was little evidence of radiographic progression (at 12 mo = 1%, 24 mo = 3%, and 44 mo = 9%). Sealant retention rates were excellent at 12 mo = 89%, 24 mo = 78%, and 44 mo = 70%. The small risk of sealant repair increased significantly as baseline ICDAS, DIAGNOdent, and QLF values increased. However, regardless of lesion severity, sealants were 100% effective at 12 mo and 98% effective over 44 mo in managing occlusal surfaces at ICDAS 0-4 ( i.e., only 4 of 228 teeth progressed to ICDAS ≥ 5 associated with sealants in need of repair and none to halfway or more through the dentin, radiographically). This study suggests that occlusal surfaces without frank cavitation (ICDAS 0-4) that are sealed with a clear sealant can be monitored with ICDAS, QLF, or DIAGNOdent, which may aid in predicting the need for sealant repair.

scholarly journals Dental Caries Diagnosis and Detection Using Neural Networks: A Systematic Review

2020 ◽  
Vol 9 (11) ◽  
pp. 3579
Author(s):  
María Prados-Privado ◽  
Javier García Villalón ◽  
Carlos Hugo Martínez-Martínez ◽  
Carlos Ivorra ◽  
Juan Carlos Prados-Frutos
Keyword(s):  
Neural Network ◽  
Systematic Review ◽  
Neural Networks ◽  
Dental Caries ◽  
Near Infrared ◽  
Data Extraction ◽  
Infrared Light ◽  
Caries Detection ◽  
Detection And Diagnosis

Dental caries is the most prevalent dental disease worldwide, and neural networks and artificial intelligence are increasingly being used in the field of dentistry. This systematic review aims to identify the state of the art of neural networks in caries detection and diagnosis. A search was conducted in PubMed, Institute of Electrical and Electronics Engineers (IEEE) Xplore, and ScienceDirect. Data extraction was performed independently by two reviewers. The quality of the selected studies was assessed using the Cochrane Handbook tool. Thirteen studies were included. Most of the included studies employed periapical, near-infrared light transillumination, and bitewing radiography. The image databases ranged from 87 to 3000 images, with a mean of 669 images. Seven of the included studies labeled the dental caries in each image by experienced dentists. Not all of the studies detailed how caries was defined, and not all detailed the type of carious lesion detected. Each study included in this review used a different neural network and different outcome metrics. All this variability complicates the conclusions that can be made about the reliability or not of a neural network to detect and diagnose caries. A comparison between neural network and dentist results is also necessary.

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