Symptoms of Depression, Acute Myocardial Infarction, and Total Mortality in a Community Sample

Circulation ◽  
1996 ◽  
Vol 93 (11) ◽  
pp. 1976-1980 ◽  
Author(s):  
John C. Barefoot ◽  
Marianne Schroll
2004 ◽  
Vol 17 (2) ◽  
pp. 114-120 ◽  
Author(s):  
Rosa Sicari ◽  
Eugenio Picano ◽  
Patrizia Landi ◽  
Emilio Pasanisi ◽  
Lucia Venneri

Open Heart ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. e001860
Author(s):  
Robert Zheng ◽  
Kenya Kusunose ◽  
Yuichiro Okushi ◽  
Yoshihiro Okayama ◽  
Michikazu Nakai ◽  
...  

BackgroundCardiovascular diseases are the second most common cause of mortality among cancer survivors, after death from cancer. We sought to assess the impact of cancer on the short-term outcomes of acute myocardial infarction (AMI), by analysing data obtained from a large-scale database.MethodsThis study was based on the Diagnosis Procedure Combination database in the Japanese Registry of All Cardiac and Vascular Diseases and the Diagnosis Procedure Combination. We identified patients who were hospitalised for primary AMI between April 2012 and March 2017. Propensity Score (PS) was estimated with logistic regression model, with cancer as the dependent variable and 21 clinically relevant covariates. The main outcome was in-hospital mortality.ResultsWe split 1 52 208 patients into two groups with or without cancer. Patients with cancer tended to be older (cancer group 73±11 years vs non-cancer group 68±13 years) and had smaller body mass index (cancer group 22.8±3.6 vs non-cancer 23.9±4.3). More patients in the non-cancer group had hypertension or dyslipidaemia than their cancer group counterparts. The non-cancer group also had a higher rate of percutaneous coronary intervention (cancer 92.6% vs non-cancer 95.2%). Patients with cancer had a higher 30-day mortality (cancer 6.0% vs non-cancer 5.3%) and total mortality (cancer 8.1% vs non-cancer 6.1%) rate, but this was statistically insignificant after PS matching.ConclusionCancer did not significantly impact short-term in-hospital mortality rates after hospitalisation for primary AMI.


ESC CardioMed ◽  
2018 ◽  
pp. 2333-2337
Author(s):  
Jorge Romero ◽  
Andrea Natale ◽  
Ricardo Avendano ◽  
Mario Garcia ◽  
Luigi Di Biase

Sudden cardiac death (SCD) is a major health problem in both the United States and worldwide. There is considerable controversy regarding the optimal time after acute myocardial infarction for risk stratification as well as the ideal time to place an implantable cardioverter defibrillator for primary prevention for SCD. Several parameters have been considered and tested for risk stratification of SCD after acute myocardial infarction. However, the only criterion that is currently being implemented is the left ventricular ejection fraction (LVEF). There are different imaging methods to measure LVEF, including echocardiography, cardiovascular magnetic resonance (CMR) imaging, nuclear scintigraphy, and angiography. When compared, these methods have shown modest correlation among them with up to 10% differences in LVEF and wide standard deviations (average 10%), which raises questions about their reliability to make decisions about primary prevention strategies for these patients. Moreover, LVEF assessment after acute myocardial infarction may be significantly affected by transient myocardial stunning and patients with a LVEF greater than 35% are not exempt from ventricular arrhythmias. Despite previous studies showing a considerably higher reduction in cardiac and total mortality when electrophysiological study is performed, current guidelines for prevention of SCD do not recommend electrophysiological study very strongly. CMR imaging has gained popularity for risk stratification of SCD. Delayed gadolinium enhancement has been proven to be useful in the identification of myocardial scar due to acute or chronic myocardial infarction. In the authors’ opinion, electrophysiological study and CMR imaging and probably strain echocardiography as well as cardiac iodine-123 metaiodobenzylguanidine will eventually play more important roles in risk stratification of patients with ischaemic cardiomyopathy based on the data published to date.


2008 ◽  
Vol 65 (10) ◽  
pp. 733-737 ◽  
Author(s):  
Vuk Mijailovic ◽  
Igor Mrdovic ◽  
Marina Ilic ◽  
Milika Asanin ◽  
Milena Srdic ◽  
...  

Background/Aim. Acute bundle branch block (ABBB) presence is associated with the increasing mortality of patients with acute myocardial infarction (AMI). The aim of this study was investigate ABBB influence with respect to in-hospital (IN) and long-term mortality in patients with AIM, as well as total mortality in follow-up, the presence of in-hospital congestive cardiac insufficiency (CCI) and the presence of CCI at follow-up. Methods. This study included 606 consecutive patients with AMI. A total of 415 (68.5%) were males and 191 (31.5%) females, mean age 64.0?11.9. After the dismissal the patients underwent 18-month follow-up period. Results. Acute bundle branch block was registered in 44 patients (7.2%), out of which 15 patients (2.4%) had the left (L) ABBB and 29 patients (4.8%) had the right (R) ABBB. The patients with ABBB showed higher proportion of IH CCI (Killip III and IV) and hypotension compared with the control group (patients without ABBB). In the group of patients with ABBB ?-blockers, statins, aspirin and ACE-inhibitors were less applied. All the three ABBB groups exhibited an increased IH mortality (ABBB 47.7% vs 11.2%, p < 0.01, ARBBB 55.1% vs 11.2% p < 0.01, ALBBB 33.3% vs 11.2%, p < 0.01). Follow-up mortality of the patients with ABBB and ALBBB was higher in comparison with the control group (log-rank p = 0.046 and log-rank p = 0.01, respectively), whereas the group with ARBBB did not show any differences (log-rank, p = 0.59). Conclusion. The patients with ABBB AMI are a risk group of patients that commonly exhibit both early and remote CCI accompanied by high mortality. That is the reason why this sub-group of AMI patients should receive an urgent diagnostics followed by aggressive therapeutic treatment. <br><br><font color="red"><b> This article has been retracted. Link to the retraction <u><a href="http://dx.doi.org/10.2298/VSP0901074U">10.2298/VSP0901074U</a></u></b></font>


Circulation ◽  
2001 ◽  
Vol 103 (suppl_1) ◽  
pp. 1349-1349
Author(s):  
Kenneth J Mukamal ◽  
Richard W Nesto ◽  
Mylan C Cohen ◽  
James E Muller

0027 Some, but not all, recent studies have found that diabetes is independently associated with long-term mortality following hospitalization for acute myocardial infarction. These studies have also failed to control for certain possible confounding factors, such as alcohol use, physical exertion, and socioeconomic status. In the Determinants of Myocardial Infarction Onset Study, trained interviewers performed chart reviews and face-to-face interviews with 1935 patients hospitalized with acute myocardial infarction between 1989 and 1993. We used Cox proportional hazards regression to determine the effect of diabetes on long-term survival after adjustment for sociodemographic characteristics, medical history, and acute infarct-related complications. Of the 1935 patients, 320 (17%) died during a median follow-up of 3.8 years. Diabetes was associated with higher total mortality in adjusted analyses (hazard ratio 1.6; 95% confidence interval, 1.3-2.1). The magnitude of the effect of diabetes was identical to that of a previous myocardial infarction. The effect of diabetes was not significantly modified by age, smoking, household income, use of thrombolytic therapy, type of hypoglycemic treatment, or duration of diagnosed diabetes, but the mortality risk associated with diabetes was higher among women than among men (adjusted hazard ratios 2.8 versus 1.3; p=0.02). In summary, diabetes is independently associated with increased mortality following acute myocardial infarction, particularly among women. The increase in risk is of the same magnitude as a previous myocardial infarction and provides further support for aggressive treatment of coronary risk factors among diabetic patients.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
S Rosato ◽  
P D'Errigo ◽  
V Manno ◽  
A Maraschini ◽  
F Cerza ◽  
...  

Abstract Background Uncertainties on long-term outcomes after acute myocardial infarction (AMI) still exist, despite the ongoing progresses in the management of patients with AMI. This study aims to appraise early and 1-year outcome of patients hospitalized due to AMI and to describe the role of heart failure (HF) as complication affecting prognoses. Methods Retrospective nationwide cohort study based on administrative data on patients with AMI admitted in all Italian hospitals from 2007 to 2017. Index admission mortality rate (I-MR), 30-day and 1-year post-discharge mortality rate (PD-MR), and 30-day and 1-year total mortality rate (T-MR) were analysed; mortality average annual changes (AC) and their 95% CI were calculated; the Cox model, adjusting for age, sex, comorbidities and length of stay, was used to analyse 1-year PD-MR Results 1,148,820 patients were considered. From 2007 to 2017, both I-MR and T-MR up to 1 year decreased significantly (from 10.9 to 8.4%; AC: -0.28%; CI: -0.31 to -0.25 and from 20.2% to 17.1%: AC: -0.33%; CI: -0.39 to -0.28, respectively). From 2010, also the rate of PD-MR decreased significantly from 11.7% to 10.4%, with such favourable trend confirmed at multivariable analyses. The HF diagnosis at the index admission is always associated with a significant increase in the risk of death (1-year T-MR average: 43% and 12% in patients with or without HF, respectively; both patients with and without HF show a constant improvement in I-MR, T-MR and PD-MR over time. Conclusions In the last decade, the remarkable improvements in the in-hospital treatment of patients with AMI and in the overall prognosis up to 1 year are confirmed by a constant decrease in both early and long-term mortality. Since complication from HF remains a dangerous condition that significantly worsens the prognosis of the AMI patient, appropriate management strategies must be identified and implemented to guarantee best results from both clinic and public health perspective. Key messages Remarkable improvements achieved in overall prognosis after AMI over the past 10 years. HF confirms to be a condition able to worsen AMI patients’ prognosis.


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