scholarly journals Hyaluronic Acid Binding Protein 2 Is a Novel Regulator of Vascular Integrity

2010 ◽  
Vol 30 (3) ◽  
pp. 483-490 ◽  
Author(s):  
Nurbek Mambetsariev ◽  
Tamara Mirzapoiazova ◽  
Bolot Mambetsariev ◽  
Saad Sammani ◽  
Frances E. Lennon ◽  
...  
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Vol 100 (5) ◽  
pp. 382-386 ◽  
Author(s):  
Yan-Bo Chen ◽  
Chuan-Tao Jiang ◽  
Guo-Qiang Zhang ◽  
Jin-Song Wang ◽  
Da Pang

Gene ◽  
1997 ◽  
Vol 190 (1) ◽  
pp. 223-225 ◽  
Author(s):  
Satarupa Das ◽  
Tushar Baran Deb ◽  
Rajeev Kumar ◽  
Kasturi Datta

Tumor Biology ◽  
2012 ◽  
Vol 34 (1) ◽  
pp. 597-608 ◽  
Author(s):  
Rajeev K Boregowda ◽  
Hitesh N. Appaiah ◽  
Mortha Karunakumar ◽  
Shivanna Parameshwariah ◽  
Geetha Avadani ◽  
...  

Oncotarget ◽  
2020 ◽  
Vol 11 (46) ◽  
pp. 4325-4337
Author(s):  
Talita Diniz Melo-Hanchuk ◽  
Carolina Colleti ◽  
Ângela Saito ◽  
Maria Carolina Santos Mendes ◽  
José Barreto Campello Carvalheira ◽  
...  

2019 ◽  
Author(s):  
Manjunath Dandi ◽  
Sunil B Kumaraswamy ◽  
Shashidhara A V ◽  
Hitesh N Appaiah ◽  
Anil Thomas ◽  
...  

Abstract Abstract Objective: Management and diagnosis of multiple human cancers remain a challenge and search for a common biomarker are still debatable. We described a method and evaluated the use of monoclonal antibody UNIVMab, to detect the protein (H11) as a common biomarker for all cancer irrespective of grade and origin . H11 protein identified as a unique Hyaluronan binding protein not detected earlier. We applied this test both with ELISA, Western blot, fractionated in anion exchange, cibacron gel exclusion, b-Hyaluronan interaction and HA-Oligo competition from various grades of Human cancers sera and processed for the detection of hyaluronan binding protein H11, reacted with Monoclonal antibody UNIVMab and with b-HA. Results: Studies from ELISA, Western blot and b-Hyaluronan interactions showed a definitive positive over-expression of UNIVMab reacted H11 antigen in all fortyfive cancer sera compared to normal sera and can be used as a common biomarker. We believe, UNIVMab detected H11 antigen, a unique hyaluronan binding protein, is a common biomarker for all cancer sera. Keywords: ELISA, Western blot, Hyaluronic acid binding protein, H11 (sera antigen), UNIVMab. Common Biomarker, Cancers Sera


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