Abstract 17063: Sleep Related Breathing Disorders and Heart Rate Variability in Young and Healthy Adults From the General Population

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Stefanie Aeschbacher ◽  
Matthias Bossard ◽  
Mirco von Rotz ◽  
Tobias Schoen ◽  
Anna Maseli ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Sleep Apnea ◽  
Large Population ◽  
Healthy Adults ◽  
Apnea Hypopnea Index ◽  
Sleep Related Breathing Disorders ◽  
Breathing Disorders ◽  
Relationship Of ◽  
The Relationship

Background: The influence of sleep related breathing disorders on heart rate variability (HRV), a measure of autonomic nervous function, is not well studied. We therefore assessed the relationship of the Apnea-Hypopnea Index (AHI) and the Oxygen Desaturation Index (ODI) with 24-hour HRV in a large population of young and healthy adults. Methods: Individuals aged between 25-41 years with a body mass index ≤35km/kg2 and without known sleep apnea syndrome (SAS) or cardiovascular disease were included in the population-based GAPP-study. A 24-hour electrocardiogram (ECG) was obtained in every participant, and systematic post-processing performed with a dedicated software. The standard deviation of all normal RR intervals (SDNN) was used as main HRV marker. AHI and ODI were obtained from nighttime pulsoxymetry with nasal airflow measurements. Sleep apnea (SA) was defined as either an AHI ≥5 or an ODI ≥5. Multivariable regression models were constructed to assess the relationship of SDNN with either AHI or ODI and to adjust for a large number of confounders. Results: We included 1266 participants (47% men) with a median age of 35 years. Mean SDNN among men and women was 162 and 148ms (p<0.0001), respectively. The proportion of participants with SA using an AHI- or ODI-based definition was 10 and 11%, respectively. Compared to individuals without SA, the beta coefficient (95% confidence interval (CI)) for SDNN was -7.48 (-14.75; -0.23, p=0.04) among those with an AHI-based SA definition, and was -11.45 (-18.39; -4.52, p=0.001) among those with an ODI-based SA definition. A highly significant inverse trend across different categories of AHI and ODI was observed, as shown in the Table. Conclusion: Early stages of sleep related breathing disorders are strongly associated with decreasing HRV in young and healthy adults, without evidence of a threshold. These findings suggest a tight link between sleep related breathing disorders and autonomic dysfunction.

scholarly journals P.2.35 Heart rate variability and sleep-related breathing disorders in commercial drivers

2019 ◽  
Vol 76 (Suppl 1) ◽  
pp. A96.1-A96
Author(s):  
Wei-te Wu ◽  
Yu-Jen Lin ◽  
Saou-Hsing Liou
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Sleep Apnea ◽  
Fasting Blood Glucose ◽  
Apnea Hypopnea Index ◽  
Sleep Related Breathing Disorders ◽  
Cross Sectional ◽  
Breathing Disorders ◽  
Obstructive Sleep ◽  
Commercial Drivers

BackgroundSleep-related breathing disorders, such as obstructive sleep apnea (OSA), seems to have an important influence on the autonomic nervous function on the heart, and associated with cardiovascular mortality. Therefore, we assessed the relations of sleep apnea-related parameters with 5 min heart rate variability (HRV) in a large cohort of male commercial drivers.MethodsThis cross-sectional study recruited 245 male bus drivers from one transportation company in Taiwan. Each participant was evaluated by a polysomnography (PSG) test and by blood lipids examination. Severity of OSA was categorized according to the apnea-hypopnea index (AHI). In addition, short-term HRV was tested.ResultsSubjects were categorized into severe OSA group (n=44; 17.9%), moderate and mild OSA group (n=117; 47.8%), and non-OSA group (n=84; 34.3%). AHI had negative correlations with SDNN (β=−0.075, p=0.007) and RMSSD (β=−0.121, p<0.001), adjusting for age, body mass index, smoking, drinking, systolic blood pressure, HDL, and fasting blood glucose. RMSSD level was decreased with severe OSA (β=−0.266, p=0.042) even adjusting for confounders.ConclusionsThe findings showed a low level of RMSSD in OSA among commercial drivers, especially in the severe group category. Decreased SDNN and RMSSD levels are associated with AHI level in commercial drivers, suggesting that they are tightly linked with autonomic dysfunction.

scholarly journals The relationship of trauma exposure to heart rate variability during wake and sleep in midlife women

2019 ◽  
Vol 57 (4) ◽  
Author(s):  
Rebecca C. Thurston ◽  
Mary Y. Carson ◽  
Karestan C. Koenen ◽  
Yuefang Chang ◽  
Karen A. Matthews ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Trauma Exposure ◽  
Midlife Women ◽  
Relationship Of ◽  
The Relationship

scholarly journals HEART RATE VARIABILITY AS A REFLECTION OF THE TONE OF THE VEGETATIVE NERVOUS SYSTEM OF SURGERY OF TUMORS OF THE REPRODUCTIVE SYSTEM OF WOMEN

2021 ◽  
Vol 2 (71) ◽  
pp. 6-9
Author(s):  
B. Kozhomberdiev ◽  
Ch. Makimbetova
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Reproductive System ◽  
Heart Rhythm ◽  
Vegetative Nervous System ◽  
Parasympathetic System ◽  
Relationship Of ◽  
The Relationship

The article presents the results of a study of heart rate variability at women after hysterectomy with appendages. There were showed the relationship of the sympathetic and parasympathetic system in the regulation of the heart rhythm. 

Treatment-Related Changes in Heart Rate Variability in Children with Sleep Apnea

2020 ◽  
Vol 162 (5) ◽  
pp. 737-745 ◽  
Author(s):  
Amal Isaiah ◽  
Dylan Bertoni ◽  
Kevin D. Pereira ◽  
Montserrat Diaz-Abad ◽  
Ron B. Mitchell ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Sleep Apnea ◽  
Secondary Analysis ◽  
Specific Treatment ◽  
Demographic Variables ◽  
Apnea Hypopnea Index ◽  
Average Heart Rate ◽  
Oxygen Desaturation Index ◽  
Obstructive Sleep

Objective Heart rate variability (HRV), a noninvasive indicator of autonomic regulation of cardiac rhythm, may represent the physiologic burden of obstructive sleep apnea (OSA). We hypothesized that the treatment-related effects of OSA on HRV in children are causally attributable to the improvement in OSA severity. Study Design Secondary analysis of outcomes from the Childhood Adenotonsillectomy Trial (CHAT). Setting Analysis of database. Subjects and Methods Time- and frequency-domain HRV parameters along with polysomnographic (PSG) and demographic variables were obtained from the CHAT study, which compared early adenotonsillectomy (eAT) to watchful waiting (WW) in children with OSA. The relative contributions of PSG variables and covariates to each HRV parameter were quantified. The proportion of changes in HRV parameters causally attributable to changes in OSA severity, measured by the apnea-hypopnea index (AHI) and oxygen desaturation index (ODI), was estimated. Results In total, 404 children aged 5 to 10 years were included. The median (interquartile range) age was 6 (3-9) years. The median body mass index percentile was 82 (53), 195 (48%) children were male, and 147 (36%) were African American. The average heart rate during PSG was the strongest independent predictor of each HRV parameter ( P < .001). Although eAT resulted in statistically significant changes in the majority of HRV parameters, these effects were not causally attributable to treatment-related changes in AHI or ODI. Conclusions The average heart rate strongly modulates HRV in children with OSA. Although eAT results in discernible changes in HRV, it appears to not be causally attributable to specific treatment-related changes in AHI or ODI.

Heart Rate and Heart-Rate Variability: An Attempt to Clarify

1968 ◽  
Vol 26 (3_suppl) ◽  
pp. 1047-1053 ◽  
Author(s):  
J. Alan Burdick ◽  
John T. Scarbrough
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Linear Relationship ◽  
Repeated Measurements ◽  
Normal Male ◽  
Resting Heart Rate ◽  
Resting Heart Rate Variability ◽  
Temporal Measures ◽  
Relationship Of ◽  
The Relationship

2 experiments were conducted to investigate a possible relationship of heart rate among and within individuals and to investigate the relationship between HR level and two temporal measures of HR variability. In Exp. 1 records for 18 normal male volunteers yielded a linear relationship between the autocorrelation and HR level which was confirmed by the data collected in Exp. 2, in which repeated measurements from 1 S were taken. Another temporal measure of variability was suggested (CVT) which combined this predictable relationship between Ra and MHR. The autocorrelation had no consistent significant association with any noted behavior or training in Exp. 2, but CVT did seem to relate to behavior. The data do not support the hypothesis that resting heart rate and resting heart-rate variability ( Ra or CVT) are reliable measures of “arousal” by themselves, rather that both are highly affected by conditions usually uncontrolled in experiments. The CVT did not significantly relate to EEG measures of arousal, taken during the wakeful state in Exp. 1.

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