Abstract P107: Differences In Hypercholesterolemia Prevalence Between African Americans And Whites: A Cross-sectional Study Using 2017-2018 National Health And Nutrition Examination Surveys Data

Importance: African Americans (AA) have a 20% higher risk of CVD death than Whites. Treating hypercholesterolemia (HC) is paramount in CVD primary prevention. Some evidence showed that AA have a lower risk of HC compared to whites. Methods: A cross-sectional study using the 2017-18 National Health and Nutrition Examination Surveys data. Logistic regression analysis was used to compare the prevalence of diagnosed HC in AA and whites aged 18-80 years old. Serum total cholesterol (TC) and high-density lipoprotein (HDL) levels were compared by multiple linear regression. Results: Among 2549 participants, 51.7% were females, and 63.4% were white. The mean (SD) age was 51.6 (19.1) years. AA had a 24 % reduced risk of HC diagnosis than whites after adjusting for age, Body Mass Index (BMI), diabetes, hypertension, and smoking; OR [95%CI]= 0.767 [0.621, 0.923]. There was no difference in TC level (p=0.7242), while HDL was higher among AA (p<0.0001, β=3.83), adjusting for age, gender, BMI, smoking, diabetes, education level, and use of cholesterol medications. Conclusion: Consistent with some evidence, AA had a lower prevalence of HC diagnosis and higher HDL levels.

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12-year Trends in Lipid Levels in Korean Children and Adolescents: A Cross-sectional Study Based on the Korea National Health and Nutrition Examination Survey

Journal of the Endocrine Society ◽

10.1210/jendso/bvab048.1338 ◽

2021 ◽

Vol 5 (Supplement_1) ◽

pp. A656-A656

Author(s):

Kyungchul Song ◽

Jeon Soyoung ◽

Hye Sun Lee ◽

Youngha Choi ◽

Jun Suk Oh ◽

...

Keyword(s):

National Health ◽

Density Lipoprotein ◽

Cross Sectional Study ◽

Overweight And Obesity ◽

Lipoprotein Cholesterol ◽

Sectional Study ◽

Lipid Levels ◽

Cross Sectional ◽

The Mean ◽

Korean Youth

Abstract Background: Dyslipidaemia at a young age is one of the risk factors of adulthood cardiovascular disease. However, investigations on the trends in lipid levels among the youth are scarce. Thus, we aimed to analyse the trends in lipid levels in Korean youth from 2007 through 2018. Methods: This cross-sectional study investigated the lipid profiles of 10,734 youths aged 10-18 years using data from the four phases of the Korea National Health and Nutritional Examination Survey: IV (2007-2009), V (2020-2012), VI (2013-2015), and VII (2016-2018). We assessed the age-, sex-, and body mass index (BMI)-adjusted mean levels of lipids at each survey. Findings: The mean levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and non-high-density lipoprotein cholesterol (non-HDL-C) levels increased from phase IV to VII. Among boys, the prevalence of subjects with acceptable levels of TC, LDL-C, and non-HDL-C decreased, whereas that of subjects with adverse levels increased from phase VI to VII. In BMI- and sex-specific analysis, adverse trends in TC, LDL-C, and non-HDL were more apparent among boys with normal BMI than among those who were overweight and obese. Among girls, the mean TC, LDL-C, and triglycerides levels increased in subjects with normal BMI and overweight. Interpretation: Our results suggest worsening trends in lipid levels and dyslipidaemia among Korean youth. These adverse trends were seen even in youth with normal BMI. These findings indicate the need for more concern about lipid levels in youth with normal BMI as well as those with overweight and obesity.

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Cross-sectional study of the association between age-related macular degeneration and arthritis in the National Health and Nutrition Examination Survey 2005–2008

BMJ Open ◽

10.1136/bmjopen-2019-035805 ◽

2020 ◽

Vol 10 (12) ◽

pp. e035805

Author(s):

Zhuoting Zhu ◽

Huan Liao ◽

Sen Liu ◽

Jian Zhang ◽

Yifan Chen ◽

...

Keyword(s):

Macular Degeneration ◽

National Health ◽

Logistic Models ◽

Cross Sectional Study ◽

Age Related Macular Degeneration ◽

Nutrition Examination Survey ◽

Sectional Study ◽

Cross Sectional ◽

Health And Nutrition ◽

Age Related

ObjectiveTo explore the association between age-related macular degeneration (AMD) and arthritis in a representative sample of the US population.DesignPopulation-based, cross-sectional study.SettingThe National Health and Nutrition Examination Survey (NHANES) 2005–2008.ParticipantsA total of 4813 participants aged 40 years and older with available information on AMD and arthritis in the 2005–2008 NHANES.MethodsThe status and types of arthritis were obtained from questionnaires. Non-mydriatic fundus photographs were collected. The types of AMD were assessed using the modified Wisconsin Age-Related Maculopathy Grading Classification Scheme. The association between arthritis and AMD was evaluated using logistic regression models.ResultsAfter adjusting for covariates, participants with any or early AMD had significantly lower odds of having any type of arthritis (any AMD: OR=0.56, 95% CI: 0.36–0.86; early AMD: OR=0.55, 95% CI: 0.34–0.88) or osteoarthritis (OA) (any AMD: OR=0.43, 95% CI: 0.26–0.71; early AMD: OR=0.44, 95% CI: 0.25–0.76) compared with those without AMD. When considering AMD as the outcome, significant negative associations were also found between any arthritis or OA and any (any arthritis: OR=0.64, 95% CI: 0.43–0.94; OA: OR=0.52, 95% CI: 0.33–0.82) or early AMD (any arthritis: OR=0.61, 95% CI: 0.40–0.93; OA: OR=0.51, 95% CI: 0.31–0.86) in the multivariable logistic models. There was no significant association between different types of arthritis and late AMD.ConclusionsPeople with arthritis, especially those with OA, were less likely to have AMD compared with those without arthritis and vice versa. Further studies are needed to confirm this potential protective effect of arthritis and/or arthritis treatment on AMD and to explore the underlying mechanisms.

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