scholarly journals Long-Term Excessive Body Weight and Adult Left Ventricular Hypertrophy Are Linked Through Later-Life Body Size and Blood Pressure

2017 ◽  
Vol 120 (10) ◽  
pp. 1614-1621 ◽  
Author(s):  
Huijie Zhang ◽  
Tao Zhang ◽  
Shengxu Li ◽  
Yajun Guo ◽  
Wei Shen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Body Size ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Later Life ◽  
Left Ventricular ◽  
Excessive Body Weight

Blood Pressure Control and Left Ventricular Hypertrophy in Long-Term Capd and Hemodialysis Patients: A Cross-Sectional Study

2003 ◽  
Vol 23 (6) ◽  
pp. 563-567 ◽  
Author(s):  
Ali Ihsan Günal ◽  
Erdogan Ilkay ◽  
Ercan Kirciman ◽  
Ilgin Karaca ◽  
Ayhan Dogukan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Left Ventricular Hypertrophy ◽  
Wall Thickness ◽  
Left Atrial ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Volume Control ◽  
Left Ventricular Chamber ◽  
Significant Difference

Background It is still not clear whether hypertension and left ventricular hypertrophy (LVH) are more common in continuous ambulatory peritoneal dialysis (CAPD) than in hemodialysis (HD) patients. Methods To examine this subject, the indices of cardiac performance were compared between 50 HD and 34 CAPD patients. Patients were further divided into two subgroups [long-term (L) CAPD and L-HD] according to dialysis modality and duration of dialysis (more than 60 months’ duration). Results The blood pressure and cardiothoracic index of CAPD patients did not differ from HD patients. On average, the left atrial index was 2 mm/m2 higher in HD patients than in CAPD patients. Left ventricular chamber sizes, wall thickness, and left ventricular mass index (LVMI) in patients on CAPD were similar to those of HD patients. Isovolumic relaxation time (IVRT) of CAPD patients was insignificantly less than that of HD patients (101 ± 22 and 115 ± 27 msec respectively). There was no significant difference between the two subgroups (L-HD and L-CAPD) in blood pressure, left atrial diameter, left ventricular chamber size, wall thickness, LVMI, ejection fraction, or IVRT. Conclusion If normovolemia and normotension are obtained by strict volume control without using antihypertensive drugs, the effects of the two modalities of chronic dialysis treatment (HD and CAPD) on cardiac structure and function are not different from each other.

Influence of Long-Term Amelioration of Anemia and Blood Pressure Control on Left Ventricular Hypertrophy in Hemodialyzed Patients

Nephron ◽  
1992 ◽  
Vol 61 (1) ◽  
pp. 21-25 ◽  
Author(s):  
Carlos Zehnder ◽  
Michel Zuber ◽  
Martin Sulzer ◽  
Beat Meyer ◽  
Edi Straumann ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Left Ventricular Hypertrophy ◽  
Blood Pressure Control ◽  
Ventricular Hypertrophy ◽  
Pressure Control ◽  
Left Ventricular

Abstract P097: Trajectories of Childhood Blood Pressure and Adult Left Ventricular Hypertrophy: The Bogalusa Heart Study

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Tao Zhang ◽  
Shengxu Li ◽  
Lydia Bazzano ◽  
Jiang He ◽  
Paul Whelton ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Later Life ◽  
Left Ventricular ◽  
Repeated Measurements ◽  
Geometric Patterns ◽  
Linear And Nonlinear ◽  
One Year ◽  
The Impact

Background: Childhood blood pressure (BP) levels predict adult left ventricular hypertrophy (LVH). However, information is limited on the association between childhood BP trajectory and adult LVH. This longitudinal study aims to characterize longitudinal BP trajectories from childhood and examine the impact of level-independent childhood BP trajectories on adult LVH and remodeling patterns. Methods: The longitudinal cohort consisted of 1,154 adults (787 whites and 367 blacks) who had repeated measurements of BP 4-15 times from childhood (4-19 years) to adulthood (20-51 years) and assessment of echocardiographic LV dimensions in adulthood. Model-estimated levels and linear slopes of BP at childhood age points were calculated in one-year intervals using the growth curve parameters and their first derivatives, respectively. Results: Linear and nonlinear curve parameters differed significantly between race-sex groups. BP showed race and sex differences from age 15 years onwards. Adults with LVH had higher long-term BP levels than normal adults in race-sex groups. Linear and nonlinear slope parameters of BP differed consistently, significantly between LVH and normal groups. Level-independent linear slopes of systolic BP showed significantly negative associations (odds ratio=0.75~0.82, p=0.001~0.015) during pre-puberty period of 4-9 years but significantly positive associations (odd ratio=1.29~1.46, p=0.001~0.008) during the puberty period of 13-19 years with adult LVH, adjusting for covariates (see the figure below). These associations were consistent across race-sex groups. Of note, the association of childhood BP linear slopes with concentric LVH was significantly stronger than that with eccentric LVH during the puberty period of 12-19 years. Conclusions: These observations indicate that the impact of BP trajectories on adult LVH and geometric patterns originates in childhood. Puberty is a crucial period for the development of LVH in later life, which has implications for early prevention.

Abstract 1562: Long-term Results (up To 19 Years) Of Balloon Angioplasty Of Coarctation Of The Aorta On Systemic Hypertension And Left Ventricular Hypertrophy.

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Walid Hassan ◽  
Mohamed Fawzy ◽  
Jehad Al Buraiki ◽  
Mohamed Al Amri ◽  
Mohamed Shoukri ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Left Ventricular Hypertrophy ◽  
Balloon Angioplasty ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Long Term Results ◽  
Systemic Hypertension ◽  
List Type

Aim : To define the long-term effect of balloon angioplasty (BA) of aortic coarctation (AC) on systemic hypertension and left ventricular hypertrophy (LVH) in adolescent and adult patients. Methods : Follow-up data of 53 patients (mean age 24 ± 9 years) undergoing BA for discrete AC at median interval of 12.5 years (range 5–19 years) including cardiac catheterization, MRI and Echocardiography form the basis of this study. Patients were divided into two groups (A&B) based on whether or not long-term antihypertensive therapy was required. Results : No early or late deaths occurred. Fifty-one patients had baseline hypertension, 49 patients had baseline LVH (92%), BA produced an immediate reduction in peak AC gradient from 66 ± 23 mmHg (95% confidence interval [CI]: 59.5 to 72.7) to 10.8 ± 7 mmHg (95% CI: 8.8 to 12.5) (p< 0.0001). Follow-up catheterization 12 months later revealed a residual gradient of 6.2 ± 6 mmHg (95% CI: 4.4 to 7.9) (p<0.001). The Doppler gradient across coarctation decreased from 59.6 ± 17 to 16 ± 8.4 mmHg at one year and 12.0 ± 6.9 mmHg at last follow-up. Left ventricular mass index (LVMI) decreased significantly in 48 patients (98%) from 132 ± 30.7 (95% CI: 122 to 141.9) to 86 ± 19.9 gram/m 2 (95% CI: 79.5 to 92.5)(p<0.0001). The systolic blood pressure decreased from 165 ± 17 mmHg (95% CI: 159 to 171) to 125 ± 10 mmHg (95% CI: 122 to 131, p<0.001) in 40 patients (group A) and from 184 ± 19 mmHg (95% CI: 169 to 198) to 142 ± 22 mmHg (95% CI: 124 to 156, p<0.001) in 11 patients (group B). The blood pressure had normalized without medication in 40 (78%) of the 51 patients (165 ± 17 mmHg to 115 ± 10 mmHg). Conclusion : Long-term results of BA for discrete AC are excellent and should be considered as first option for treatment of this disease; Regression of LVH (≥ 20% reduction in LVMI) occurred in 98% of patients after BA and only 22% of patients required medications for hypertension.

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