scholarly journals Development of a New Method for Endovascular Aortic Repair: Combination Therapy of Cell Transplantation and Stent Grafts With a Drug Delivery System

Circulation ◽  
2006 ◽  
Vol 114 (1_suppl) ◽  
pp. I-378-I-383 ◽  
Author(s):  
M. Kajimoto
Keyword(s):  
Drug Delivery ◽  
Combination Therapy ◽  
Drug Delivery System ◽  
Cell Transplantation ◽  
Delivery System ◽  
Endovascular Aortic Repair ◽  
New Method ◽  
Stent Grafts ◽  
Aortic Repair

Topology Optimization of MEMS-Based Biodegradable Controlled Drug Delivery System for Combination Therapy

2007 ◽  
Author(s):  
Ruixia Yu ◽  
Hualing Chen ◽  
Tianning Chen ◽  
Hairong Wang
Keyword(s):  
Drug Delivery ◽  
Topology Optimization ◽  
Controlled Release ◽  
Combination Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Release System ◽  
Evolutionary Structural Optimization ◽  
Controlled Drug Delivery System ◽  
Controlled Release System

MEMS-based biodegradable controlled release system with micro multi-chambers can respectively enclose two drugs in different chambers to realize a combination therapy. In order to synchronously obtain the linear release of two drugs, it is necessary to completely investigate the topology optimization of the system. This paper introduces the theory of multi-objective topology optimization into MEMS-based biodegradable controlled release system for the combination therapy. Furthermore, a new method of CA-based evolutionary structural optimization (CA-ESO) is presented to accomplish the topology optimization of this controlled release system. The result shows that the optimized drug delivery system can achieve the objective of the synchronizing linear release for two drugs. The conclusion illustrates that the CA-ESO method proposed in this paper is validity for the topology optimization of MEMS-based biodegradable controlled release system.

A multifunctional near-infrared laser-triggered drug delivery system using folic acid conjugated chitosan oligosaccharide encapsulated gold nanorods for targeted chemo-photothermal therapy

2019 ◽  
Vol 7 (24) ◽  
pp. 3811-3825 ◽  
Author(s):  
Panchanathan Manivasagan ◽  
Seung Won Jun ◽  
Van Tu Nguyen ◽  
Nguyen Thanh Phong Truong ◽  
Giang Hoang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Folic Acid ◽  
Combination Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Infrared Laser ◽  
Chitosan Oligosaccharide

FA–COS–TGA–GNRs–DOX have been successfully designed as a drug delivery system for chemo-photothermal combination therapy.

In situ gel-forming dual drug delivery system for synergistic combination therapy of colorectal peritoneal carcinomatosis

RSC Advances ◽  
2015 ◽  
Vol 5 (123) ◽  
pp. 101494-101506 ◽  
Author(s):  
Xiaoling Li ◽  
Rangrang Fan ◽  
Yuelong Wang ◽  
Min Wu ◽  
Aiping Tong ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Combination Therapy ◽  
Peritoneal Carcinomatosis ◽  
Drug Delivery System ◽  
Delivery System ◽  
Local Drug Delivery ◽  
In Situ Gel ◽  
Local Drug Delivery System ◽  
Dual Drug

A novel local drug delivery system composed of docetaxel loaded micelles and an oxaliplatin loaded hydrogel was fabricated and proved to be potentially useful in the treatment of colorectal peritoneal carcinomatosis.

PTX encapsulated by an XG–DOX conjugate for combination therapy against multi-drug resistance

RSC Advances ◽  
2016 ◽  
Vol 6 (109) ◽  
pp. 107606-107612 ◽  
Author(s):  
Zhuli Huang ◽  
Xuan Xie ◽  
Jean Felix Mukerabigwi ◽  
Chang Wang ◽  
Shufang Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Combination Therapy ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Delivery System ◽  
Multi Drug Resistance ◽  
New Type ◽  
Dual Drug

A new type of targeted dual drug delivery system was designed and possesses outstanding advantages over ordinary systems, proving effective against MDR cancer cells.

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