scholarly journals Long-Term Evolution of Functional Limitations in Stroke Survivors Compared With Stroke-Free Controls: Findings From 15 Years of Follow-Up Across 3 International Surveys of Aging

Stroke ◽  
2021 ◽  
Author(s):  
Andres Gil-Salcedo ◽  
Aline Dugravot ◽  
Aurore Fayosse ◽  
Louis Jacob ◽  
Mikaela Bloomberg ◽  
...  
Keyword(s):  
Scale Score ◽  
Functional Limitations ◽  
Chronic Phase ◽  
Long Term Evolution ◽  
Stroke Survivors ◽  
Modified Rankin Scale ◽  
Term Evolution ◽  
Disability Level

Background and Purpose: In the chronic phase 2 to 5 years poststroke, limitations in activities of daily living (ADL) and instrumental ADL (IADL) initially plateau before steady increasing. However, the impact of age and differences in initial levels of disability on the evolution of these limitations remains unclear. As such, this study aims to evaluate differences in long-term evolution of ADL/IADL limitations between stroke survivors and stroke-free population, and how limitations differ by initial level of disability for stroke survivors. Methods: Thirty-three thousand six hundred sixty participants (5610 first-ever stroke cases with no recurrence during follow-up and 28 050 stroke-free controls) aged ≥50 from the Health and Retirement Study, Survey of Health, Ageing and Retirement in Europe, and English Longitudinal Study of Ageing were assessed for number of ADL/IADL limitations during the poststroke chronic phase (for cases) and over follow-up years 1996 to 2018 (for controls). Three thousand seven hundred eighteen stroke cases were additionally categorized by disability level using the modified Rankin Scale score of 1 to 2 years poststroke. Evolution of ADL/IADL limitations was assessed in stroke cases and controls and by modified Rankin Scale score (0–1, 2–3, 4–5) using linear mixed models. Models were stratified by age group (50–74 and ≥75 years) and adjusted for baseline characteristics, health behaviors, BMI, and comorbidities. Results: Findings showed relative stability of ADL/IADL limitations during 3 to 6 years poststroke followed by an increase for both populations, which was faster for younger stroke cases, suggesting a differential age-effect ( P <0.001). Disability level at 1 to 2 years poststroke influenced the evolution of limitations over time, especially for severe disability (modified Rankin Scale score, 4–5) associated with a reduction in limitations at 5 to 6 years poststroke. Conclusions: Our findings showed that during the poststroke chronic phase functional limitations first plateau and then increase and the evolution differs by disability severity. These results highlight the importance of adaptive long-term health and social care measures for stroke survivors.

Long-term Results of Enterprise Stent-Assisted Coiling of Cerebral Aneurysms

Neurosurgery ◽  
2012 ◽  
Vol 71 (2) ◽  
pp. 239-244 ◽  
Author(s):  
Kyle M. Fargen ◽  
Brian L. Hoh ◽  
Babu G. Welch ◽  
G. Lee Pride ◽  
Giuseppe Lanzino ◽  
...  
Keyword(s):  
Scale Score ◽  
Cerebral Aneurysms ◽  
High Volume ◽  
Vascular Reconstruction ◽  
Long Term Results ◽  
Modified Rankin Scale ◽  
Volume Data ◽  
Stent System

Abstract BACKGROUND: The Enterprise Vascular Reconstruction Device and Delivery System (Cordis; the Enterprise stent) was approved for use in conjunction with coiling of wide-necked aneurysms in 2007. No published long-term aneurysm occlusion or complication data exist for the Enterprise system. OBJECTIVE: We compiled data on consecutive patients treated with Enterprise stent-assisted coiling of aneurysms from 9 high-volume neurointerventional centers. METHODS: A 9 center registry was created to evaluate large volume data on the delayed safety and efficacy of the Enterprise stent system. Pooled data were compiled for consecutive patients undergoing Enterprise stent-assisted coiling at each institution prior to May 2009. RESULTS: Two-hundred twenty-nine patients with 229 aneurysms, 32 of which were ruptured aneurysms, were included in the study. Mean clinical and angiographic follow-up was 619.6 ± 26.4 days and 655.7 ± 25.2 days, respectively. Mean aneurysm size was 9.2 ± 0.4 mm. Fifty-nine percent of patients demonstrated 100% coil obliteration and 81% had 90% or higher occlusion at last follow-up angiography. A total of 19 patients (8.3%) underwent retreatment of their aneurysms during the follow-up period. Angiographic in-stent stenosis was seen in 3.4% and thromboembolic events occurred in 4.4%. Overall, 90% of patients who underwent Enterprise-assisted coiling had a modified Rankin Scale score of 2 or less at last follow-up. A poor modified Rankin Scale score was strongly associated with rupture status (P &lt; .001). CONCLUSION: Although this study is limited by its retrospective nature, the Enterprise stent system appears to be an effective, safe, and durable treatment for intracranial aneurysms when used in conjunction with coiling.

scholarly journals Long term evolution of soft tissue response in the fingers of high-level sport climbers: A cross-sectional 10 Year follow-up study

2021 ◽  
Vol 52 ◽  
pp. 173-179
Author(s):  
Stefan Fröhlich ◽  
Andreas Schweizer ◽  
Lisa Reissner ◽  
Tatjana Pastor ◽  
Jörg Spörri ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Long Term Evolution ◽  
Tissue Response ◽  
Cross Sectional ◽  
Follow Up Study ◽  
Term Evolution ◽  
Soft Tissue Response ◽  
High Level

Long-term Evolution of Hepatocellular Adenomas at MRI Follow-up

Radiology ◽  
2021 ◽  
Vol 298 (1) ◽  
pp. E57-E58
Author(s):  
Nora Frulio ◽  
Charles Balabaud ◽  
Hervé Trillaud ◽  
Paulette Bioulac-Sage
Keyword(s):  
Long Term Evolution ◽  
Term Evolution ◽  
Hepatocellular Adenomas

Long-term Evolution of Hepatocellular Adenomas at MRI Follow-up

Radiology ◽  
2020 ◽  
Vol 295 (2) ◽  
pp. 361-372 ◽  
Author(s):  
Federica Vernuccio ◽  
Maxime Ronot ◽  
Marco Dioguardi Burgio ◽  
François Cauchy ◽  
Kingshuk R. Choudhury ◽  
...  
Keyword(s):  
Long Term Evolution ◽  
Term Evolution ◽  
Hepatocellular Adenomas

Abstract 1122‐000087: Long‐Term Outcomes of Anterior Communicating Artery Aneurysm Treated with Coiling: Subset Analysis of SMART Registry

2021 ◽  
Vol 1 (S1) ◽  
Author(s):  
Clemens M Schirmer ◽  
Richard J Bellon ◽  
Bradley N Bohnstedt ◽  
Reade A DeLeacy ◽  
Min S Park ◽  
...  
Keyword(s):  
Adverse Events ◽  
Scale Score ◽  
Unruptured Aneurysm ◽  
Anterior Communicating Artery ◽  
Modified Rankin Scale ◽  
Serious Adverse Events ◽  
Large Aneurysm ◽  
Small Aneurysm

Introduction : The purpose of this study was to assess the long‐term clinical outcomes of anterior communicating artery (ACoA) aneurysm treated with coiling. Methods : Data on patients with an ACoA aneurysm were extracted from a prospective multicenter registry (SMART) that enrolled patients with intracranial aneurysms or other neurovascular abnormalities who underwent coiling. The primary effectiveness outcome was retreatment through follow‐up, and the primary safety outcome was procedural device‐related serious adverse events within 24 hours. Results : Of the 995 adults enrolled in the SMART registry, 230 had an ACoA aneurysm (Table). The average patient age was 59.1 years (SD 12.5), and 62.6% were female. A modified Rankin Scale score of 0 to 2 was present in 89.6% of patients. Most aneurysms were small (93.9%) and saccular (87.8%). The aneurysm was wide necked in 57.7% of patients and was ruptured in 35.7%. Coiling was stent assisted in 39.1% of patients and balloon assisted in 14.8%. Retreatment through follow‐up occurred in 8.1% (15/185) of patients—6.8% (12/176) of patients with a small aneurysm, 33.3% (3/9) of patients with a large aneurysm, 4.0% (5/126) of patients with an unruptured aneurysm, 16.9% (10/59) of patients with a ruptured aneurysm, 9.9% (9/91) of patients with unassisted coiling, 5.6% (4/71) of patients with stent‐assisted coiling, and 7.4% (2/27) of patients with balloon‐assisted coiling. Procedural device‐related serious adverse events within 24 hours occurred in 5.2% of patients—5.1% (11/216) of patients with a small aneurysm, 7.1% (1/14) of patients with a large aneurysm, 6.1% (9/148) of patients with an unruptured aneurysm, 3.7% (3/82) of patients with a ruptured aneurysm, 3.6% (4/111) of patients with unassisted coiling, 5.6% (5/90) of patients with stent‐assisted coiling, and 11.8% (4/34) of patients with balloon‐assisted coiling. No deaths occurred within 24 hours of the procedure. At 1 year, 91.8% (167/182) of patients had a Raymond–Roy Occlusion Classification of Class I or II. From immediately after the procedure to 1 year, progressive occlusion was observed in 29.1% (53/182) of patients, and stable occlusion was observed in 56.6% (103/182) of patients. At 1 year, the all‐cause mortality rate was 4.3%, and at a 1‐year follow‐up, a modified Rankin Scale score of 0 to 2 was present in 86.2% (112/130) of patients. Conclusions : Coiling of ACoA aneurysm was safe and had durable 1‐year results.

scholarly journals The incidence of experimental smoking in school children: an 8-year follow-up of the child and adolescent behaviors in long-term evolution (CABLE) study

2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Hsing-Yi Chang ◽  
Wen-Chi Wu ◽  
Chi-Chen Wu ◽  
Jennifer Y Cheng ◽  
Baai-Shyun Hurng ◽  
...  
Keyword(s):  
School Children ◽  
Child And Adolescent ◽  
Long Term Evolution ◽  
Term Evolution
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