Role of Pleural Mesothelial Cells in the Production of the Submesothelial Connective Tissue Matrix of Lung

1984 ◽  
Vol 130 (2) ◽  
pp. 267-274 ◽  
Author(s):  
Stephen I. Rennard ◽  
Marie-Claude Jaurand ◽  
Jean Bignon ◽  
Oichi Kawanami ◽  
Victor J. Ferrans ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Mesothelial Cells ◽  
Pleural Mesothelial Cells ◽  
Connective Tissue Matrix ◽  
Tissue Matrix

Strategies For Immunodissection Of The Connective Tissue Matrix And Basement Membranes

1999 ◽  
Vol 5 (S2) ◽  
pp. 1222-1223
Author(s):  
Douglas R. Keene ◽  
Sara F. Tufa
Keyword(s):  
Connective Tissue ◽  
Elastic Fiber ◽  
Dry Weight ◽  
Basement Membranes ◽  
The Matrix ◽  
Connective Tissue Matrix ◽  
Main Component ◽  
Tissue Matrix ◽  
And Task

Connective tissue matrices are quite diversified and include that composing skin, tendon, bone, cartilage, cornea and many others. The main component of the connective tissue matrix is collagen, composing approximately 70% of the dry weight of the human body. More members of the collagen family are discovered each year, with over twenty types described to date. Many of these collagens are tissue specific. In addition to the collagens, the connective tissue matrix is also the residence of epithelial and endothelial basement membranes and many other molecules including a variety of proteoglycans and elastic fiber components. The cells within the matrix are highly differentiated and task specific.Using immunocytochemical technique applied at the level of the electron microscope, we have focused our resources to understand the structure and functional role of these matrix molecules.

Role of oxygen derivatives in the cytotoxicity and DNA damage produced by asbestos on rat pleural mesothelial cells in vitro

1994 ◽  
Vol 15 (6) ◽  
pp. 1251-1255 ◽  
Author(s):  
Hang Ying Dong ◽  
Annie Buard ◽  
Annie Renier ◽  
Francoise Lévy ◽  
Laure Saint-Etienne ◽  
...  
Keyword(s):  
Dna Damage ◽  
Mesothelial Cells ◽  
Pleural Mesothelial Cells

Toward a kinetic theory of connective tissue micromechanics

1993 ◽  
Vol 74 (2) ◽  
pp. 665-681 ◽  
Author(s):  
S. M. Mijailovich ◽  
D. Stamenovic ◽  
J. J. Fredberg
Keyword(s):  
Connective Tissue ◽  
Three Dimensional ◽  
Elastic Fibers ◽  
Tissue Elasticity ◽  
Field Equations ◽  
Fiber Network ◽  
Rate Dependent ◽  
Connective Tissue Matrix ◽  
Tissue Matrix ◽  
And Diffusion

The aim of this study is to develop unifying concepts at the microstructural level to account for macroscopic connective tissue dynamics. We establish the hypothesis that rate-dependent and rate-independent dissipative stresses arise in the interaction among fibers in the connective tissue matrix. A quantitative theoretical analysis is specified in terms of geometry and material properties of connective tissue fibers and surrounding constituents. The analysis leads to the notion of slip and diffusion boundary layers, which become unifying concepts in understanding mechanisms that underlie connective tissue elasticity and energy dissipation during various types of loading. The complex three-dimensional fiber network is simplified to the interaction of two ideally elastic fibers that dissipate energy on slipping interface surfaces. The effects of such interactions are assumed to be expressed in the aggregate matrix. Special solutions of the field equations are obtained analytically, whereas the general solution of the model field equations is obtained numerically. The solutions lead to predictions of tissue behavior that are qualitatively, if not quantitatively, consistent with reports of a variety of dynamic moduli, their dependencies on the rate and amplitude of load application, and some features associated with preconditioning.

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