Medical Image Analysis Based on Endoscopic Radiofrequency Ablation Catheter System on the Treatment of Gastroesophageal Reflux Disease

2019 ◽  
Vol 9 (2) ◽  
pp. 395-399
Author(s):  
Wei-Tao Liang ◽  
Tao Li ◽  
Zhong-Gao Wang ◽  
Ji-Min Wu ◽  
Zhi-Wei Hu ◽  
...  
Keyword(s):  
Chest Pain ◽  
Radiofrequency Ablation ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Medical Image Analysis ◽  
Final Analysis ◽  
Ablation Procedure ◽  
Atypical Symptoms ◽  
Symptom Scores

Objective: Gastroesophagel reflux disease is not readily diagnosed using X-ray or even computer tomography. This study was to evaluate the endoscopic imaging for the radiofrequency ablation (RA) on the diagnosis and management of gastroesophageal reflux disease. Methods: We allocated 85 to mechanical RA and 80 patients to LTF. Primary outcome measures, including symptom scores of heartburn, regurgitation, chest pain, belching, hiccup, cough and asthma as well as proton pump inhibitors (PPIs) use, were analyzed. Results: There were 125 patients following mechanical radiofrequency ablation procedure (N = 60) or LTF (N = 65) included in the final analysis. The symptom scores were all significantly decreased as compared with the corresponding values before the two procedures in both groups (p < 0.05). After mechanical RA procedure and LTF, 30 (50%) and 45 (69.2%) patients in each group achieved complete PPIs therapy independence (p = 0.028). Comparing with LTF, the mechanical RA procedure had less effect on improving typical symptoms of heartburn and chest pain and the rate of reoperation (13% vs. 0, p = 0.003). Conclusions: Comparing with LTF in controlling GERD symptoms, the mechanical radiofrequency ablation procedure can offer equivalent relief on atypical symptoms. However, it has less effect on improving PPIs independence and avoiding reoperation.

Medical Image Analysis Based on Endoscopic Radiofrequency Ablation Catheter System on the Treatment of Gastroesophageal Reflux Disease Related Extra-Esophageal Symptoms

2019 ◽  
Vol 9 (8) ◽  
pp. 1765-1769
Author(s):  
Wei-Tao Liang ◽  
Tao Li ◽  
Ji-Min Wu ◽  
Zhi-Wei Hu ◽  
Chao Yan ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Statistical Significance ◽  
Medical Image Analysis ◽  
Final Analysis ◽  
Symptom Scores ◽  
Endoscopic Radiofrequency Ablation

Objective: Gastroesophageal reflux disease is easily missed on X-ray or even computer tomography. This study was to evaluate the endoscopic imaging for the radiofrequency ablation (RA) on the diagnosis and management of gastroesophageal reflux disease related extra-esophageal symptoms. Methods: From January 2011, to January 2012, we allocated 51 patients to LTF and 47 to RA procedure. Primary outcome measures, including symptom scores of globus hysterics, chest pain, belching, hiccup, cough and asthma as well as proton pump inhibitors (PPIs) use, were analyzed after 5-year follow-up. Results: There were 90 patients following RA procedure (N = 40) or LTF (N = 50) that completed the designated 5-year follow-up and were included in the final analysis. At the end of 5-year follow-up, the symptom scores were all significantly decreased as compared with the corresponding values before the two procedures in both groups (p < 0.05). Moreover, the improvement in symptom scores between the two groups did not achieve statistical significance. After RA procedure and LTF, 18 (45%) and 32 (64%) patients in each group achieved complete PPIs therapy independence (p = 0.071). Comparing with LTF, however, the RA procedure had a higher risk of reoperation (17.5% vs. 0, p = 0.002). Conclusion: Comparing with LTF in controlling GERD-related extra-esophageal symptoms, RA procedure can offer equivalent relief on symptoms and PPIs independence. However, it has a higher risk of reoperation during the 5 years follow-up.

scholarly journals Endoscopic cardial constriction with band ligation in the treatment of refractory gastroesophageal reflux disease: a preliminary feasibility study

2021 ◽  
Author(s):  
Zhi-Tong Li ◽  
Feng Ji ◽  
Xin-Wei Han ◽  
Rui Zhang ◽  
Li-Dong Chen ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Symptom Relief ◽  
Final Analysis ◽  
Band Ligation ◽  
Post Surgery ◽  
Esophageal Ph ◽  
Symptom Scores ◽  
Invasive Method

Abstract Background Gastroesophageal reflux disease (GERD) is a common digestive disease, could cause extra-esophageal symptoms. Peroral endoscopic cardial constriction with band ligation (PECC-b) is a minimally invasive method for the treatment of GERD in recent years. The goals of this study were to evaluate the clinical efficacy of PECC-b to treat gastroesophageal reflux-related symptoms. Methods A retrospective study of patients undergoing PECC-b between January 2017 and December 2018 at a single institution was conducted. All patients confirmed GERD by endoscopy, esophageal PH-impedance monitoring, esophageal manometry and symptom questionnaires. The outcome measures included reflux-related scores, patients’ satisfaction and drug independence after 12 months following surgery. Results A total of 68 patients, with follow-up of 12 months post surgery, were included in the final analysis. The symptom scores were all significantly decreased as compared with preoperation (P < 0.05). The esophageal symptom scores showed a better improvement than extra-esophageal symptoms (P < 0.001). Fifty-three (77.9%) patients achieved complete drug therapy independence and 52 (76.5%) patients were completely or partially satisfied with the symptom relief following surgery. Conclusions The PECC-b is a safe, effective and recommended approach for the control of GERD-related symptoms. Further multicenter prospective studies are required to confirm these outcomes.

Gastroesophageal Reflux Disease: A Gastroenterologist's Perspective

2011 ◽  
Vol 21 (3) ◽  
pp. 89-99
Author(s):  
Michael F. Vaezi
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Best Practice ◽  
Clinical Care ◽  
Diagnostic Testing ◽  
Diagnostic Tools ◽  
Swallowing Function ◽  
Atypical Symptoms

Gastroesophageal reflux disease (GERD) is a commonly diagnosed condition often associated with the typical symptoms of heartburn and regurgitation, although it may present with atypical symptoms such as chest pain, hoarseness, chronic cough, and asthma. In most cases, the patient's reduced quality of life drives clinical care and diagnostic testing. Because of its widespread impact on voice and swallowing function as well as its social implications, it is important that speech-language pathologists (SLPs) understand the nature of GERD and its consequences. The purpose of this article is to summarize the nature of GERD and GERD-related complications such as GERD-related peptic stricture, Barrett's esophagus and adenocarcinoma, and laryngeal manifestations of GERD from a gastroenterologist's perspective. It is critical that SLPs who work with a multidisciplinary team understand terminology, diagnostic tools, and treatment to ensure best practice.

scholarly journals Diagnosis and management of gastroesophageal reflux disease

2014 ◽  
Vol 27 (3) ◽  
pp. 210-215 ◽  
Author(s):  
Maria Aparecida Coelho de Arruda Henry
Keyword(s):  
Quality Of Life ◽  
Surgical Treatment ◽  
Gastroesophageal Reflux Disease ◽  
Drug Use ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Disease Diagnosis ◽  
Clinical Treatment ◽  
Atypical Symptoms

INTRODUCTION: Gastroesophageal reflux disease (GERD) is probably one of the most prevalent diseases in the world that also compromises the quality of life of the affected significantly. Its incidence in Brazil is 12%, corresponding to 20 million individuals. OBJECTIVE: To update the GERD management and the new trends on diagnosis and treatment, reviewing the international and Brazilian experience on it. METHOD: The literature review was based on papers published on Medline/Pubmed, SciELO, Lilacs, Embase and Cochrane crossing the following headings: gastroesophageal reflux disease, diagnosis, clinical treatment, surgery, fundoplication. RESULTS: Various factors are involved on GERD physiopathology, the most important being the transient lower esophageal sphincter relaxation. Clinical manifestations are heartburn, regurgitation (typical symptoms), cough, chest pain, asthma, hoarseness and throat clearing (atypical symptoms), which may be followed or not by typical symptoms. GERD patients may present complications such as peptic stenosis, hemorrhage, and Barrett's esophagus, which is the most important predisposing factor to adenocarcinoma. The GERD diagnosis must be based on the anamnesis and the symptoms must be evaluated in terms of duration, intensity, frequency, triggering and relief factors, pattern of evolution and impact on the patient's quality of life. The diagnosis requires confirmation with different exams. The goal of the clinical treatment is to relieve the symptoms and surgical treatment is indicated for patients who require continued drug use, with intolerance to prolonged clinical treatment and with GERD complications. CONCLUSION: GERD is a major digestive health problem and affect 12% of Brazilian people. The anamnesis is fundamental for the diagnosis of GERD, with special analysis of the typical and atypical symptoms (duration, intensity, frequency, triggering and relief factors, evolution and impact on the life quality). High digestive endoscopy and esophageal pHmetry are the most sensitive diagnosctic methods. The clinical treatment is useful in controlling the symptoms; however, the great problem is keeping the patients asymptomatic over time. Surgical treatment is indicated for patients who required continued drug use, intolerant to the drugs and with complicated forms of GERD.

scholarly journals Food patterns in Russian patients with gastroesophageal reflux disease: the results of pilot comparative study

2020 ◽  
Vol 92 (8) ◽  
pp. 66-72
Author(s):  
V. S. Kropochev ◽  
S. V. Morozov ◽  
M. A. Lantseva ◽  
A. N. Sasunova ◽  
V. I. Pilipenko ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Healthy Eating ◽  
Reflux Disease ◽  
Final Analysis ◽  
Control Group ◽  
Esophageal Ph ◽  
Symptom Evaluation ◽  
Source Data ◽  
Acid Exposure Time

Aim. To evaluate nutritional patterns in patients with gastroesophageal reflux disease (GERD) compared to the control group without GERD. Materials and methods. The data of complex examination of patients referred to perform esophageal pH-impedance recording and who gave written informed consent to participate in the study served as a source data. All the participants underwent complex examination, including clinical data (presence of heartburn and acid regurgitation), symptom evaluation (GERD-Q questionnaire), esophagogastroscopy, esophageal pH-impedance recordings and food frequency questionnaire. Diagnosis of GERD was based on GERD-Q score 8, acid exposure time 6%, number of gastroesophageal refluxes 80/day by 24-hrs esophageal pH-impedance recordings. Nutritional patterns were assessed with the use of healthy eating pyramid principles. Results. Overall 165 patients were enrolled and the data of 150 of them (34 with confirmed GERD and 116 of the control group) were available for the final analysis. The patients of the both groups consumed lower compared to the recommended amounts of dairy and higher amounts of meat. Those with GERD consumed larger amounts of fruits (0.910.68 compared to the values of healthy eating pyramid vs 0.520.57 in the control group, p=0.001), and fats (0.690.55 vs 0.490.55, p=0.001). Compared to the controls, patients with GERD consumed lower amounts of vegetables (0.860.46 of the healthy eating pyramid vs 0.940.63 in the control group, р=0.004) and sugars confectionaries (0.380.39 vs 1.930.98, p=0.0001). Conclusion. Nutritional patterns of patients with gastroesophageal reflux disease significantly differ compared to the control group. The obtained data may be used for diet modification in patients with arterial hypertension.

scholarly journals CLINICAL PRESENTATION FEATURES IN THE ORAL CAVITY PATIENTS WITH GASTROESOPHAGEAL REFLUX DISEASE

2020 ◽  
pp. 5-8
Author(s):  
O.P. Kerzyuk ◽  
N.M. Rozhko ◽  
A.V. Kindrat
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Oral Cavity ◽  
Oral Mucosa ◽  
Reflux Disease ◽  
Social Issues ◽  
Atypical Symptoms ◽  
Periodontal Tissues ◽  
Number Of Patients

Nowadays, gastroesophageal reflux disease (GERD) is particularly relevant because it concerns many health and social issues. According to international and national statistics, the number of GERD patients is constantly increasing, especially among the socially active segments of the population. GERD is one of the most important problems of modern gastroenterology due to the increase in the number of patients with this pathology, the presence of both typical and atypical symptoms significantly impair the quality of patients’ life. Atypical symptoms of GERD may lead to overdiagnosis of some diseases and worsen their course; sometimes patients run the risk of developing serious complications with the need of long-term medical treatment in case of insufficient awareness of physicians about GERD. Increased attention should be given to issues of concomitant pathology of the oral cavity and diseases of the esophagus taking into account the anatomical proximity, the commonness of the blood supply, innervation and humoral regulation, because the mouth is the first division of the alimentary canal. Therefore, all GERD-associated changes in the oral cavity can be divided into change in soft tissues (the vermilion border, mucosa, tongue, periodontal tissues) and hard tissues of teeth and a deterioration of the content and quality of oral fluid. Our study aimed at examining the prevalence and variation of pathological changes in the oral mucosa of GERD patients. We examined 90 patients aged 25–35 years and 45–55 years. Patients were divided into 3 groups of 30 patients in each group: 1 group – patients with diagnosed GERD with high acidity; 2 group – patients with low acidity, 3 group – control. The patients have been examined by a gastroenterologist based on generally accepted criteria, esophageal pH monitoring data as well as fibrogastroduodenoscopy of esophagus and stomach. Dental assessment included evaluating the state of oral hygiene (index Green-Vermilion), and oral mucosa condition; the periodontal status was assessed by the index Rassel. In conclusion, the findings indicate a variety of changes in oral cavity in patients with GERD, both with high and with low acidity. The prospect of our further research will be to develop an algorithm for diagnosis and treatment of oral GERD manifestations and secondary dental disease prevention.

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