The Role of X and CT Image Measurement in Hip Arthroplasty in Patients with Parkinson's Disease

Objective: The study aims at evaluating if X-ray and spiral CT imaging is efficient in patients with Parkinson's disease after total hip arthroplasty (THA). Method: 76 patients with Parkinson combined with hip disease were selected as the study subjects, and grouped into the control group and the experimental group. Before surgery, X-ray and spiral CT were used to detect the data of abduction angle and the front rake of the healthy side of the patient, so as to perform THA as the reference value. In addition, Harris score was adopted to evaluate hip function 3 months after surgery in both groups. Also, the progression of Parkinson after operation was evaluated by Hoehn-Yahr grading method, and the complications were analyzed. Results: The results showed that the abduction angle measured by X-ray was 48.39 ± 4.15°, and the front rake was 13.83 ± 6.27°. In the experimental group, the abduction angle obtained by spiral CT measurement was 46.26 ± 3.92°, and the front rake was 12.44 ± 4.52°. The unequal length of limb was 1.10 ± 0.42 cm in the control group and 0.42 ± 0.21 cm in the experimental group. Moreover, the unequal length of limb in the two groups was significantly smaller than that before surgery (P < 0.01). The hip joint score of the two groups after surgery was apparently higher (P < 0.01), and the experimental group had significantly higher hip joint score (P < 0.05). Additionally, the experimental group had obviously higher Harris score of Parkinson's disease progression (P < 0.05). The occurrence rate of postoperative complications in the control group and the experimental group was 9.09% and 7.69%, respectively, which was not greatly different (P > 0.05). Conclusion: THA based on the data of spiral CT image measurement can achieve better postoperative results, which is conducive to recovering hip joint function and treating Parkinson's disease, and provides experimental basis for the diagnosis and treatment of Parkinson's disease in later clinical.

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Effects of a core stabilization training program on balance ability in persons with Parkinson’s disease: a randomized controlled trial

Clinical Rehabilitation ◽

10.1177/0269215520918631 ◽

2020 ◽

Vol 34 (6) ◽

pp. 764-772

Author(s):

Irene Cabrera-Martos ◽

Ana Teresa Jiménez-Martín ◽

Laura López-López ◽

Janet Rodríguez-Torres ◽

Araceli Ortiz-Rubio ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Center Of Pressure ◽

Dynamic Balance ◽

Controlled Trial ◽

Core Stability ◽

Control Group ◽

Balance Confidence ◽

Balance Ability ◽

Experimental Group

Objective: To explore the effects of an eight-week core stability program on balance ability in persons with Parkinson’s disease. Design: Randomized controlled trial. Setting: A local Parkinson’s association. Subjects: A total of 44 participants with a clinical diagnosis of Parkinson’s disease were randomly assigned to an experimental ( n = 22) or control group ( n = 22). Intervention: The experimental group received 24 sessions of core training, while the control group received an intervention including active joint mobilization, muscle stretching, and motor coordination exercises. Main measures: The primary outcome measure was dynamic balance evaluated using the Mini-Balance Evaluation Systems Test. Secondary outcomes included the balance confidence assessed with the Activities-specific Balance Confidence Scale and standing balance assessed by the maximal excursion of center of pressure during the Modified Clinical Test of Sensory Interaction on Balance and the Limits of Stability test. Results: After treatment, a significant between-group improvement in dynamic balance was observed in the experimental group compared to the control group (change, 2.75 ± 1.80 vs 0.38 ± 2.15, P = 0.002). The experimental group also showed a significant improvement in confidence (change, 16.48 ± 16.21 vs 3.05 ± 13.53, P = 0.047) and maximal excursion of center of pressure in forward (change, 0.86 ± 1.89 cm vs 0.17 ± 0.26 cm, P = 0.048), left (change, 0.88 ± 2.63 cm vs 0.07 ± 0.48 cm, P = 0.010), and right (change, 1.63 ± 2.82 cm vs 0.05 ± 0.17 cm, P = 0.046) directions of limits of stability compared to the control group. Conclusion: A program based on core stability in comparison with non-specific exercise benefits dynamic balance and confidence and increases center of mass excursion in patients with Parkinson’s disease.

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Leap motion controlled video game-based therapy for upper limb rehabilitation in patients with Parkinson’s disease: a feasibility study

Journal of NeuroEngineering and Rehabilitation ◽

10.1186/s12984-019-0593-x ◽

2019 ◽

Vol 16 (1) ◽

Cited By ~ 6

Author(s):

Pilar Fernández-González ◽

María Carratalá-Tejada ◽

Esther Monge-Pereira ◽

Susana Collado-Vázquez ◽

Patricia Sánchez-Herrera Baeza ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Feasibility Study ◽

Upper Limb ◽

Serious Games ◽

Post Treatment ◽

Control Group ◽

Leap Motion ◽

Affected Side ◽

Experimental Group

Abstract Background Non-immersive video games are currently being used as technological rehabilitation tools for individuals with Parkinson’s disease (PD). The aim of this feasibility study was to evaluate the effectiveness of the Leap Motion Controller® (LMC) system used with serious games designed for the upper limb (UL), as well as the levels of satisfaction and compliance among patients in mild-to-moderate stages of the disease. Methods A non-probabilistic sampling of non-consecutive cases was performed. 23 PD patients, in stages II-IV of the Hoehn & Yahr scale, were randomized into two groups: an experimental group (n = 12) who received treatment based on serious games designed by the research team using the LMC system for the UL, and a control group (n = 11) who received a specific intervention for the UL. Grip muscle strength, coordination, speed of movements, fine and gross UL dexterity, as well as satisfaction and compliance, were assessed in both groups pre-treatment and post-treatment. Results Within the experimental group, significant improvements were observed in all post-treatment assessments, except for Box and Blocks test for the less affected side. Clinical improvements were observed for all assessments in the control group. Statistical intergroup analysis showed significant improvements in coordination, speed of movements and fine motor dexterity scores on the more affected side of patients in the experimental group. Conclusions The LMC system and the serious games designed may be a feasible rehabilitation tool for the improvement of coordination, speed of movements and fine UL dexterity in PD patients. Further studies are needed to confirm these preliminary findings.

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Feasibility of a Brazilian samba protocol for patients with Parkinson's disease: a clinical non-randomized study

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x20190140 ◽

2020 ◽

Vol 78 (1) ◽

pp. 13-20 ◽

Cited By ~ 1

Author(s):

Ana Cristina TILLMANN ◽

Alessandra SWAROWSKY ◽

Clynton Lourenço CORRÊA ◽

Alexandro ANDRADE ◽

Jéssica MORATELLI ◽

...

Keyword(s):

Quality Of Life ◽

Parkinson’S Disease ◽

Parkinson's Disease ◽

Randomized Study ◽

General Information ◽

Control Group ◽

Action Strategies ◽

And Control ◽

Experimental Group

Abstract Background: New protocols applied in the rehabilitation of Parkinson's disease enable different action strategies for health professionals, as well as a new range of activities for these individuals. However, no valid samba protocol with activity prescription for this population was found in the literature. Objective: To investigate the feasibility of a Brazilian samba protocol in individuals with Parkinson's disease. Methods: Twenty participants, mean age of 66.4±10.7 years, diagnosed with idiopathic Parkinson 's disease, divided into: experimental group that received the intervention of Brazilian samba dance classes (10 individuals); and control group that maintained their routine activities (10 individuals). For data collection, a divided questionnaire was used: General Information; Disability stages scale; Balance and Quality of Life. Results: During class implementation, there were no falls, as all dance activities adhered to the details of the protocol steps without any changes. On average, patients completed 82.7% of activities. After 12 weeks, the experimental group had improvements in the UPDRS global score, in daily activities, and on motor examination. There was also improvement in balance scores and in the mobility domain of the quality of life in the experimental group. Conclusion: The samba protocol seems to be feasible and safe for patients with PD. Moreover, it has pleasant characteristics and offers sufficient physical benefits for combination with drug treatment. There were also benefits in social relationships and as a possible rehabilitation tool in individuals with Parkinson's disease.

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A randomized controlled study of whether setting specific goals improves the effectiveness of therapy in people with Parkinson’s disease

Clinical Rehabilitation ◽

10.1177/0269215518815217 ◽

2018 ◽

Vol 33 (3) ◽

pp. 465-472 ◽

Cited By ~ 3

Author(s):

Irene Cabrera-Martos ◽

Araceli Ortiz-Rubio ◽

Irene Torres-Sánchez ◽

Janet Rodríguez-Torres ◽

Laura López-López ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Grip Strength ◽

Goal Attainment ◽

Hand Grip Strength ◽

Manual Dexterity ◽

Control Group ◽

Randomized Controlled ◽

Hand Grip ◽

Experimental Group

Objective: To evaluate the effects of an intervention based on a specific set of goals on goal attainment, manual dexterity, hand grip strength and finger prehension force compared to a standardized approach in patients with Parkinson’s disease. Design: Randomized controlled trial. Setting: Home-based. Participants: Fifty patients with a clinical diagnosis of Parkinson’s disease acknowledging impaired manual ability were randomized into two groups. Interventions: Patients in the experimental group ( n = 25) were included in an intervention focused on task components that involved goals proposed by participants. Patients in the control group ( n = 25) received a standard intervention focused on impairments in range of motion, grasp and manipulation. Home condition and duration (four weeks, twice a week) were similar in both groups. Main outcome measures: The primary outcome measure was goal achievement assessed with the Goal Attainment Scaling. Secondary outcomes were manual dexterity evaluated with the Purdue Pegboard Test and hand grip strength and finger prehension force assessed using a dynamometer. Results: After four weeks, significant between-group improvement in goal attainment was observed in the experimental group (change 17.36 ± 7.48 vs. 4.03 ± 6.43, P < 0.001). Compared to the control group, the experimental group also showed a significant improvement ( P < 0.05) in manual dexterity (postintervention values in the most affected arm 10.55 ± 1.95 vs. 7.33 ± 3.63 pins, P < 0.001) and finger prehension force (postintervention values in the most affected arm 8.03 ± 1.93 vs. 6.31 ± 1.85 kg, P = 0.010). Conclusions: Targeting therapy toward specific goals leads to greater changes in arm function than a standardized approach in people with Parkinson’s disease.

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The Effect of Transcranial Direct Current Stimulation Combined with Visual Cueing Training on Motor Function, Balance, and Gait Ability of Patients with Parkinson’s Disease

Medicina ◽

10.3390/medicina57111146 ◽

2021 ◽

Vol 57 (11) ◽

pp. 1146

Author(s):

Si-a Lee ◽

Myoung-Kwon Kim

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Motor Function ◽

Direct Current ◽

Transcranial Direct Current Stimulation ◽

Control Group ◽

Visual Training ◽

Direct Current Stimulation ◽

Visual Cueing ◽

Experimental Group

Background and Objectives: The purpose of this study was to investigate the effects of transcranial direct current stimulation (tDCS) on motor function, balance and gait ability in patients with Parkinson’s disease (PD). Materials and Methods: For the experiment, 30 patients with PD were randomly assigned to the experimental group (n = 15) and the control group (n = 15). Visual cueing training was commonly applied to both groups, the experimental group applied tDCS simultaneously with visual training, and the control group applied sham tDCS simultaneously with visual training. All subjects were pre-tested before the first intervention, post-tested after completing all 4 weeks of intervention, and followed-up tested 2 weeks after the completing intervention. The tests used the Unified Parkinson’s Disease Rating Scale (UPDRS) for motor function assessment, Functional Gait Assessment (FGA) for balance assessment, Freezing of Gait Questionnaire (FOG-Q) and the GAITRite system for gait ability assessment. Among the data obtained through the GAITRite system, gait velocity, cadence, step time, double support time, and stride length were analyzed. Results: The experimental group showed a significant decrease in UPDRS and a significant increase in FGA and cadence after the intervention. In addition, UPDRS and cadence showed a significant difference in the follow-up test compared to the pre-intervention test. Conclusions: This study suggests that the application of tDCS to the supplementary motor area of PD patients is useful as an adjuvant therapy for rehabilitation training of PD patients.

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ASPECTOS DE LA PERSONALIDAD Y PERSONALIDAD PRE-MÓRBIDA EN LA ENFERMEDAD DE PARKINSON

International Journal of Developmental and Educational Psychology Revista INFAD de psicología ◽

10.17060/ijodaep.2014.n1.v5.668 ◽

2016 ◽

Vol 5 (1) ◽

pp. 195

Author(s):

Charles Rodrigues ◽

Florencio Vicente Castro ◽

Paula Figueiredo

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Normal Aging ◽

Personality Inventory ◽

Control Group ◽

Premorbid Personality ◽

Experimental Group

Abstract.This research aimed to identify and analyze the changes in personality and premorbid personality among elderly with Parkinson’s disease and elderly with normal aging. The sample consisted by 340 participants, where personality was assessed with 170 participants divided by two groups: experimental group (EG), with 40 participants, average age of M = 82,23, diagnosed with Parkinson’s disease and a control group (CG), with 45 participants with average age of M = 83,47 with normal aging. For evaluation of the premorbid personality had participated 170 caregivers, divided in identical conditions to the above groups. The instrument applied for seniors and caregivers was the personality inventory NEO-FFI. The results didn’t show significant differences in the Parkinson’s personality, while the premorbid personality showed differences in extroversion and agreeableness.Key words: Parkinson, personality, premorbid personality.Resumen.Esta investigación pretendió identificar y analizar las alteraciones de personalidad y personalidad pre-mórbida, entre mayores con la enfermedad de Parkinson y mayores en fase de envejecimiento normal. La muestra fue constituida por 340 participantes, donde la personalidad se evaluó con 170 mayores divididos por dos grupos: grupo experimental (GE), con 40 participantes de edad media M = 82,23 y diagnostico de Parkinson, y el grupo de control (GC), con 45 participantes con una edad media M = 83,47 y en fase de envejecimiento normal. Para la evaluación de la personalidad pre-mórbida participaron 170 cuidadores divididos en grupos idénticos a los anteriores. El instrumento aplicado para mayores y cuidadores fue el inventario de personalidad NEO-FFI. Los resultados no presentaron diferencias significativas en la personalidad de Parkinson, mientras que la personalidad pre-mórbida presentó diferencias en la extroversión y amabilidad.Palabras-clave: Parkinson, personalidad, personalidad pre-mórbida.

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Individualized guidance and telephone monitoring in a self-supervised home-based physiotherapeutic program in Parkinson

Fisioterapia em Movimento ◽

10.1590/1980-5918.030.003.ao14 ◽

2017 ◽

Vol 30 (3) ◽

pp. 559-568

Author(s):

Ihana Thaís Guerra de Oliveira Gondim ◽

Carla Cabral dos Santos Accioly Lins ◽

Nadja Maria Jorge Asano ◽

Amdore Guescel C Asano ◽

Etenildo Dantas Cabral ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Randomized Clinical Trials ◽

Rating Scale ◽

Physical Therapist ◽

Well Being ◽

Control Group ◽

Positive Effects ◽

Therapeutic Exercises ◽

Experimental Group

Abstract Introduction: Home therapeutic exercises have been a target of interest in the treatment of the Parkinson's disease (PD). The way that the physical therapist guides and monitors these exercises can impact the success of therapy. Objective: To evaluate the effects of individualized orientation and monitoring by telephone in a self-supervised home therapeutic exercise program on signs and symptoms of PD and quality of life (QoL). Methods: Single-blind randomized clinical trials with 28 people with PD (Hoehn and Yahr 1 to 3). Patients were randomized into two groups: experimental and control. The experimental group had a meeting with individualized guidance about physiotherapy exercises present in a manual, received the manual to guide their activities at home and obtained subsequent weekly monitoring by telephone. The control group received the usual cares by the service. Both were orientated to carry out exercises three times a week during 12 weeks. Was evaluated: (1) activities of daily living (ADL) and motor examination sections of the Unified Parkinson's Disease Rating Scale (UPDRS) and QoL by the Parkinson Disease Questionnaire 39 (PDQ-39). The analysis between groups was performed by the Mann-Whitney test and intragroup through the Wilcoxon (p < 0.05). Results: Significant improvement in ADL (p= 0.001) and motor examination (p= 0.0008) of the UPDRS, PDQ-39 total (p = 0.027) and dimensions mobility (p = 0.027), emotional well-being (p= 0.021) and bodily discomfort (p = 0.027) in the experimental group compared to the control group. Conclusion: The individualized guidance and weekly monitoring by telephone in a self-supervised home therapeutic exercises program promoted positive effects on ADL, motor examination and QoL of people in early stages of PD.

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Effects of Acupuncture & Qigong Meditation on Nonmotor Symptoms of Parkinson’s Disease

Journal of Acupuncture Research ◽

10.13045/jar.2020.00066 ◽

2020 ◽

Vol 37 (4) ◽

pp. 247-253

Author(s):

Jaejong Kim ◽

Ki Heang Cho ◽

So jung An ◽

Shanqin Cui ◽

Sun Wook Kim ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Large Scale ◽

Rating Scales ◽

Control Group ◽

Nonmotor Symptoms ◽

Before And After ◽

Disease Rating ◽

Experimental Group ◽

Smell Identification

Background: Parkinson's disease(PD) affects not only motor symptoms, but also nonmotor symptoms. This study is a clinical trial to determine whether Qigong and acupuncture affect nonmotor symptoms of PD.Methods: A 2-arm parallel and randomized trial was performed with 21 participants who had received either Qigong meditation only [control group (CG)] or acupuncture and Qigong meditation [experimental group (EG)]. The participants' levels of the discomfort in nonmotor symptoms from Parkinson's disease were evaluated by using the Unified Parkinson's Disease Rating Scales (UPDRS 1) and Test of Smell Identification (TSI) before and after 12 treatments at baseline and 1 month after 12 treatments.Results: The both CG and EG showed improvements in the UPDRS 1 score after treatment by 5.6 ± 5.15 (p= 0.003; 74%) and 4.8 ± 3.80 (p = 0.004; 79%), respectively. The both CG and the EG did improvements in the TSI after treatment by 10.3 ± 4.37 (p < 0.001; 84%) and 12.6 ± 1.77 (p = 0.022; 100%), respectively. However, statistical differences were not observed between the CG and the EG using the UPDRS 1 and the TSI scores.Conclusion: The combination of Qigong and acupuncture and Qigong alone was shown to improve the nonmotor symptoms and olfactory function of PD. In the future, large-scale clinical studies on alternative treatment for PD and studies on mechanisms affecting nonmotor symptoms of acupuncture and Qigong are needed.

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Improved Quantitative Susceptibility Mapping under Laplace Algorithm in Diagnosis of Parkinson’s Disease

Scientific Programming ◽

10.1155/2021/8210526 ◽

2021 ◽

Vol 2021 ◽

pp. 1-9

Author(s):

Guangxi Chen ◽

Liang Zeng ◽

Liu Yang ◽

Yixian Yu ◽

Panli Sun ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Magnetic Susceptibility ◽

Image Quality ◽

Diagnostic Accuracy ◽

Susceptibility Mapping ◽

Control Group ◽

Dice Similarity Coefficient ◽

Quantitative Susceptibility Mapping ◽

Experimental Group

To explore the application value of quantitative susceptibility mapping (QSM) based on Laplace algorithm in the diagnosis of Parkinson’s disease, 48 Parkinson’s disease patients admitted to our hospital were included as the research objects. They were randomly divided into control group (24 cases) and experimental group (24 cases). All patients underwent quantitative magnetic susceptibility imaging scan. In the experimental group, the improved Laplace algorithm was used for QSM diagnosis, while in the control group, conventional QSM diagnosis was used. Through calculations of precision, recall, dice similarity coefficient, intersection-over-union (IoU), and area under the curve (AUC), the quality improvement effect of the improved Laplace algorithm for QSM image was assessed. Then, the diagnostic accuracy of the algorithm was verified by comparing with the results of QSM image diagnosis in Parkinson’s patients without algorithm processing. The results showed that compared with the traditional Laplace algorithm, the improved Laplace algorithm can considerably reduce the image noise level ( P < 0.05 ). The dice, IoU, precision, and recall rate of image quality evaluation indicator were considerably improved ( P < 0.05 ), and the AUC reached 0.896. There were no significant differences in fraction anisotropy (FA) and mean diffusivity (MD) between the two groups ( P > 0.05 ) and no significant differences in magnetic susceptibility of brain nuclei between the two groups ( P > 0.05 ). However, they all showed high magnetic susceptibility in the substantia nigra region of the brain. Compared with the control group, the diagnostic accuracy of the experimental group was 97.5 ± 1.23%, which was considerably higher than that of the control group (86.5 ± 3.56%) ( P < 0.05 ). In short, the image quality of QSM based on Laplace improved algorithm was greatly improved, and the diagnostic accuracy of PD was also greatly improved, which was worthy of promotion in the field of clinical QSM imaging diagnosis of PD.

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