Anti-Inflammatory Effects of Lutein in Retinal Ischemic/Hypoxic Injury: In Vivo and In Vitro Studies

African plants have been used for medicinal purposes for many centuries. Many of these African medicinal plants are assumed to be safe but have yet to be scientifically validated. Aspalathus linearis (rooibos) is a commercialised South African tea recognised for its phytopharmaceutical potential. Aspalathus linearis (rooibos) has been gaining popularity globally for its health benefits and accepted as a nutraceutical due to the growing evidence of its efficacy. The bioactive constituents found in Aspalathus linearis (rooibos) have been reported to exert both anti-inflammatory and antioxidant activity however a few in vitro studies has suggested otherwise. Aspalathus linearis (rooibos) has shown to modify the actions of the immune system by influencing the regulation of messenger molecules like cytokines and nitric oxide however most of these studies have been conducted in vitro with a very few studies reaching in vivo application. Divergent in vitro cell models has shown to produce varying results regarding cytokine and nitric oxide NO activity of Aspalathus linearis (rooibos). This review highlights recent studies on the (NO) and cytokine activities of Aspalathus linearis (rooibos) both in vitro and in vivo. Most studies report on its anti-inflammatory and antioxidant activity however a few in vitro studies suggests opposite effects which should be considered for prolonged use especially when prescribed in a supplementation form. Many studies have looked at aspects of safety and toxicity of Aspalathus linearis (rooibos) however no complete toxicological studies have been done as yet.International Journal of Human and Health Sciences Vol. 03 No. 03 July’19. Page: 150-157

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Abnormal Sensitivity of Cortisol-Producing Adrenocortical Adenomas to Serotonin: In Vivo and in Vitro Studies

Yearbook of Endocrinology ◽

10.1016/s0084-3741(08)70169-0 ◽

2007 ◽

Vol 2007 ◽

pp. 358-361

Author(s):

D.E. Schteingart

Keyword(s):

In Vitro Studies ◽

Adrenocortical Adenomas

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In vitro and in vivo evaluation of the anti-inflammatory effects of Arzanol from Helichrysum italicum

Planta Medica ◽

10.1055/s-0030-1264369 ◽

2010 ◽

Vol 76 (12) ◽

Author(s):

J Bauer ◽

F Dehm ◽

A Koeberle ◽

F Pollastro ◽

G Appendino ◽

...

Keyword(s):

In Vivo Evaluation ◽

Anti Inflammatory

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Haemanthus coccineus extract shows profound anti-inflammatory actions in vitro and in vivo due to its main alkaloid narciclasine

Planta Medica ◽

10.1055/s-0035-1565331 ◽

2015 ◽

Vol 81 (16) ◽

Author(s):

S Fuchs ◽

LT Hsieh ◽

W Saarberg ◽

CAJ Erdelmeier ◽

TA Wichelhaus ◽

...

Keyword(s):

Anti Inflammatory

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The Venom of the Boomslang (Dispholidus Typus): In Vivo and in Vitro Studies

Thrombosis and Haemostasis ◽

10.1055/s-0038-1653532 ◽

1969 ◽

Vol 21 (02) ◽

pp. 234-244 ◽

Cited By ~ 5

Author(s):

N Mackay ◽

J.C Ferguson ◽

Antonia Bagshawe ◽

A.T.T Forrester ◽

G.P Mcnicol

Keyword(s):

In Vitro Studies

SummaryAn account is given of the effects of boomslang venom in man. Evidence was found of a fibrinolytic state apparently secondary to the coagulant action of the venom. These features rapidly responded to the administration of specific antivenom. In vitro studies, using a homogenate of boomslang parotids, confirmed the coagulant properties of the venom and showed them to be of much greater potency than the proteolytic actions.

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