Computerized tomography and neuropsychological test measures in adolescents with obsessive-compulsive disorder

1984 ◽  
Vol 141 (3) ◽  
pp. 363-369 ◽  
Author(s):  
Sarah Alaa Mohsen ◽  
Fatma Ahmed El Deeb ◽  
Ehab Sayed Ramadan ◽  
Mai Abd El-Raouf Eissa

Background: Obsessive compulsive disorder (OCD) is a common and potentially debilitating disorder. Neuropsychological assessment provides unique complementary information that is critical for evaluating higher cortical abilities. This study aimed to assess the neuropsychological functions in OCD patients which can then point to the brain structures or pathways and to study the correlation between these assessments and different clinical variables. Methods: This cross-sectional case control study had included sixty patients who were divided into two groups, Group I: thirty OCD patients diagnosed by DSM-IV and Group II: thirty healthy controls who were recruited from the community, matched with patients’ age, gender, and education. Results: The age of onset in our study was 19.13 ± 0.35 years, the mean duration was 7.44 ± 3.88 years, 40% of the studied cases had severe OCD symptoms and 33.3% of them were compulsive cleaners. There was a high significant difference between the two groups regarding WCST in favor of the control group. There was a high significant difference between the two groups regarding ROCF where the control group showed better results than the OCD patients. Conclusions: Neuropsychological test performance remains an informative and objective means of investigation, especially when applied to psychiatric disorders. The executive functions in OCD patients were impaired in comparison to the normal study subjects.


1989 ◽  
Vol 25 (7) ◽  
pp. A9
Author(s):  
John R. Debus ◽  
Michael D. Devous ◽  
John W. Cain ◽  
John Battaglia ◽  
S.Nadeem Ahmed ◽  
...  

1995 ◽  
Vol 29 (2) ◽  
pp. 293-298 ◽  
Author(s):  
Steven Cumming ◽  
Phillipa Hay ◽  
Teresa Lee ◽  
Perminder Sachdev

Seventeen obsessive-compulsive disorder patients treated with psychosurgery were administered a comprehensive neuropsychological test battery. Their performance on neuropsychological testing was compared with that of an age and severity matched sample of 17 OCD sufferers who had not received psychosurgery. The psychosurgery and control groups did not differ in intellectual or memory functioning, consistent with earlier findings that psychosurgery does not reduce global ability estimates. The psychosurgery group performed more poorly than the control group on an adaptation of the Wisconsin Card Sorting Test, demonstrating the possible impact of frontal lobe lesions on the abilities underpinning the formation and shifting of response sets.


1991 ◽  
Vol 5 (3) ◽  
pp. 225-235 ◽  
Author(s):  
David C. Rettew ◽  
Deborah L. Cheslow ◽  
Judith L. Rapoport ◽  
Henrietta L. Leonard ◽  
Marge C. Lenane ◽  
...  

2015 ◽  
Vol 56 (8) ◽  
pp. 837-847 ◽  
Author(s):  
Amitai Abramovitch ◽  
Jonathan S. Abramowitz ◽  
Andrew Mittelman ◽  
Abigail Stark ◽  
Kesley Ramsey ◽  
...  

2011 ◽  
Vol 26 (S2) ◽  
pp. 150-150 ◽  
Author(s):  
S. Sottocorno ◽  
R. Martoni ◽  
E. Galimberti ◽  
E. Fadda ◽  
L. Bellodi

IntroductionSome authors suggest that Anorexia Nervosa (AN) could be considered as part of the Obsessive Compulsive Spectrum. Obsessive-compulsive disorder (OCD) might be best characterized in terms of failures in cognitive and behavioral inhibitory functions. Impairments in intentionally inhibiting simple motor actions (Response Inhibition) have been demonstrated in these patients but no studies were conducted in AN patients.ObjectiveThe aim of this study was to evaluate Response Inhibition (RI) in patients with Obsessive Compulsive Disorder (OCD), patients with Anorexia Nervosa (AN) and Healthy Controls (HC).Methods29 HC, 17 patients with OCD and 15 patients with AN were recruited. Stop Signal Task (SST) selected from Cambridge Neuropsychological Test Automated Battery (CANTAB) was administered to all participants. SST is based on the Logan's theory and it gives an index of Response Inhibition, called Stop Signal Reaction Time (SSRT).ResultsA significant difference in SSRT between HC and the clinical groups was found. No differences in SSRT and number of “Direction Errors” were found between OCD and AN groups. No gender influence on the SST performance was found.OCD group showed slower reaction times to the main task than AN and HC.ConclusionResults from neuropsychological assessment have shown a deficit in the Response Inhibition in OCD and AN patients, in line with our hypothesis. Findings supports evidences in literature about OCD patients, but it represents a pioneer result in the contest of AN patients.


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