The Sequential Bithermal Binaural Caloric Test: I. A Statistical Analysis of Normal Subject Responses

1973 ◽  
Vol 82 (3) ◽  
pp. 3-8 ◽  
Author(s):  
David D. Custer ◽  
Franklin O. Black ◽  
William G. Hemenway ◽  
John I. Thornby
Keyword(s):  
Statistical Analysis ◽  
Confidence Intervals ◽  
Normal Subjects ◽  
Significant Response ◽  
Caloric Test ◽  
Test Results ◽  
Normal Limits ◽  
Normal Subject

Statistical analysis of bithermal binaural caloric test results gave a statistically significant response difference between ears for right-handed normal subjects. There were no significant response differences due to temperature of stimulation or due to the interaction between temperature of stimulation and ear stimulated. Of the four different orders of stimulation tested, all were statistically equivalent. Because intrasubject variance from a statistical analysis of normal subject responses was evidently much smaller than percentage based variance, the use of absolute differences or confidence intervals for determination of normal limits should yield more precise normal criteria than percentage based comparisons allow.

The Sequential Bithermal Binaural Caloric Test

1973 ◽  
Vol 82 (6_suppl) ◽  
pp. 3-8
Keyword(s):  
Statistical Analysis ◽  
Confidence Intervals ◽  
Normal Subjects ◽  
Significant Response ◽  
Caloric Test ◽  
Test Results ◽  
Normal Limits ◽  
Normal Subject

Statistical analysis of bithermal binaural caloric test results gave a statistically significant response difference between ears for right-handed normal subjects. There were no significant response differences due to temperature of stimulation or due to the interaction between temperature of stimulation and ear stimulated. Of the four different orders of stimulation tested, all were statistically equivalent. Because intrasubject variance from a statistical analysis of normal subject responses was evidently much smaller than percentage based variance, the use of absolute differences or confidence intervals for determination of normal limits should yield more precise normal criteria than percentage based comparisons allow.

Identification of N-Monoacetylcystine in Uraemic Plasma

1981 ◽  
Vol 60 (3) ◽  
pp. 331-334 ◽  
Author(s):  
F. Gejyo ◽  
G. Ito ◽  
Y. Kinoshita
Keyword(s):  
Plasma Levels ◽  
Gel Filtration ◽  
Normal Subjects ◽  
Exchange Chromatography ◽  
Cysteic Acid ◽  
Homocysteic Acid ◽  
Normal Limits ◽  
Acidic Nature ◽  
Sulphur Amino Acids

1. An unidentified ninhydrin-positive substance of an acidic nature was detected in the plasma of uraemic patients. This substance was isolated from haemodialysate by ion-exchange chromatography and gel filtration, and identified as a sulphur-containing amino acid: N-monoacetylcystine. 2. The quantitative determination of sulphur amino acids in plasma revealed that the plasma levels of cysteic acid, homocysteic acid, taurine, cystine and cystathionine as well as N-monoacetylcystine in uraemic patients were markedly higher than in normal subjects (P < 0.001 for each). However, the plasma levels of methionine in uraemic patients were within normal limits.

Reference Values for Serial Vestibular Testing

1986 ◽  
Vol 95 (1) ◽  
pp. 83-90 ◽  
Author(s):  
Leonard Proctor ◽  
Robert Glackin ◽  
Craig Smith ◽  
Hiroshi Shimizu ◽  
Paul Lietman
Keyword(s):  
Reference Values ◽  
Test Scores ◽  
Vestibular Function ◽  
Normal Subjects ◽  
Caloric Test ◽  
Initial Value ◽  
Short Acting ◽  
Normal Limits ◽  
Vestibular Testing ◽  
Directional Preponderance

This study defines the normal limits of day-to-day variation in vestibular function. A short-acting caloric test was used and nystagmus intensity was measured by means of an interactive computerized technique. Data were analyzed from 30 normal subjects tested on three successive days and from ten of these subjects who were also tested on 11 additional occasions. Individual caloric test scores generally remained between 55% and 170% of their initial value; narrower ranges resulted when scores were averaged together. There was very little habituation of caloric responses. The upper normal limits of test-retest variation in scores for right-left difference and directional preponderance of caloric responses were 24% and 22%, respectively.

Experimental Determination of the Influence of an Air Entraining Additive on the Resistance of Concrete to Chemical Defrosting Agents

2016 ◽  
Vol 714 ◽  
pp. 165-170
Author(s):  
Dalibor Kocáb ◽  
Petr Misák ◽  
Monika Králíková ◽  
Tereza Komárková
Keyword(s):  
Surface Layer ◽  
Statistical Analysis ◽  
Experimental Determination ◽  
Hardened Concrete ◽  
Test Results ◽  
Cement Concrete

The paper describes the results of an experiment performed as part of the GAČR 13-18870S project dealing with the durability characteristics of the surface layer of hardened concrete. The paper aims to evaluate the experimental determination of the influence of an air entraining additive on the resistance of cement concrete to water and defrosting chemicals. For the purposes of the experiment 4 mixtures were prepared which differed in the amount of air entraining additive and the amount of cement. The test results were evaluated using statistical analysis of experiment.

The Sequential Bithermal Binaural Caloric Test: II. Clinical Application of New Statistical Methods for Interpretation

1973 ◽  
Vol 82 (3) ◽  
pp. 9-14 ◽  
Author(s):  
Franklin O. Black ◽  
David D. Custer ◽  
William G. Hemenway ◽  
John I. Thornby
Keyword(s):  
Statistical Methods ◽  
Caloric Test ◽  
Clinical Procedures ◽  
Normal Limits ◽  
Increased Sensitivity ◽  
Caloric Nystagmus ◽  
Stimulus Temperature ◽  
Retrospective Examination ◽  
Preliminary Support

Three tests for the determination of caloric nystagmus response abnormalities have been developed, based upon analysis of intrasubject normal responses, obtained by using a statistical model that provided an exact fit with clinical procedures. Normal limits derived from interaural, stimulus temperature, and nystagmus direction responses should provide a more sensitive index of abnormality than limits based on percentage based response criteria. A retrospective examination of caloric responses from Ménière's disease patients provided preliminary support for clinical feasibility and increased sensitivity of the statistical methods advocated for clinical usage.

Correlation between bithermal caloric test results and vestibular evoked myogenic potentials (VEMPs) in normal subjects

2012 ◽  
Vol 270 (5) ◽  
pp. 1623-1628 ◽  
Author(s):  
Isabel Vaamonde Sanchez Andrade ◽  
Sofia Santos-Perez ◽  
Pilar Gayoso Diz ◽  
Torcuato Labella Caballero ◽  
Andrés Soto-Varela
Keyword(s):  
Normal Subjects ◽  
Vestibular Evoked Myogenic Potentials ◽  
Caloric Test ◽  
Test Results

2. Results in Normal Subjects

1977 ◽  
Vol 86 (5_suppl3) ◽  
pp. 7-23 ◽  
Author(s):  
Andrew W. Sills ◽  
Robert W. Baloh ◽  
Vicente Honrubia
Keyword(s):  
Data Analysis ◽  
Standard Deviation ◽  
Confidence Intervals ◽  
Statistical Tests ◽  
Normal Subjects ◽  
Testing Procedure ◽  
Caloric Test ◽  
Resultant Data

A large number of variables were examined simultaneously for 43 normal subjects over the four irrigations of a caloric test. Care was used for every step of the testing procedure and data analysis to eliminate as much of the variance in the caloric responses as possible. The normality of each variable's distribution was examined using the Wilk-Shapiro W test and corrected if necessary by the best of several transformations. The means, standard deviation, and 95% confidence intervals of the resultant data were derived. Statistical tests of temperature, sidedness, and directionality were done on the variables and several important sources of variance were found and explained.

Determination of Factor XIII Activity and of Factor XIII Inhibitors Using an Ammonium-Sensitive Electrode

1983 ◽  
Vol 50 (02) ◽  
pp. 563-566 ◽  
Author(s):  
P Hellstern ◽  
K Schilz ◽  
G von Blohn ◽  
E Wenzel
Keyword(s):  
Factor Xiii ◽  
Normal Subjects ◽  
The Other ◽  
Activity Measurement ◽  
Factor Xiii Deficiency ◽  
Assay Procedure ◽  
Stabilization Factor ◽  
Release Method ◽  
Sensitive Electrode

SummaryAn assay for rapid factor XIII activity measurement has been developed based on the determination of the ammonium released during fibrin stabilization. Factor XIII was activated by thrombin and calcium. Ammonium was measured by an ammonium-sensitive electrode. It was demonstrated that the assay procedure yields accurate and precise results and that factor XIII-catalyzed fibrin stabilization can be measured kinetically. The amount of ammonium released during the first 90 min of fibrin stabilization was found to be 7.8 ± 0.5 moles per mole fibrinogen, which is in agreement with the findings of other authors. In 15 normal subjects and in 15 patients suffering from diseases with suspected factor XIII deficiency there was a satisfactory correlation between the results obtained by the “ammonium-release-method”, Bohn’s method, and the immunological assay (r1 = 0.65; r2= 0.70; p<0.01). In 3 of 5 patients with paraproteinemias the values of factor XIII activity determined by the ammonium-release method were markedly lower than those estimated by the other methods. It could be shown that inhibitor mechanisms were responsible for these discrepancies.

Sign in / Sign up

Export Citation Format

Share Document