Intravenous Drug Use, the Combination of Drugs and Sexual Activity and HIV Infection among Gay and Bisexual Men: The San Francisco Men's Health Study

1989 ◽  
Vol 19 (1) ◽  
pp. 57-73 ◽  
Author(s):  
Ron Stall ◽  
David G. Ostrow

This paper describes a sizeable subgroup of the AIDS caseload that has not been widely studied, that is, men with histories of both male homosexual activity and intravenous drug use. In this paper we identify differences and similarities between gay intravenous drug users and gay men with different histories of drug use; examine the relationship between HIV seropositivity and different patterns of drug use; and estimate whether gay intravenous drug users are more likely than other gay men to be a source of continued HIV transmission.

2008 ◽  
Vol 6 (2) ◽  
pp. 42-46 ◽  
Author(s):  
Jelena Ravlija ◽  
Sandra Puvačić ◽  
Zlatko Puvačić ◽  
Ivan Curić

In the period between 1991-2004, in the Federation of Bosnia and Herzegovina there were altogether 59 registered HIV positive persons, out of those 43 were clinically diagnosed with AIDS. Gender-wise, 83% of the infected were male, and 17% female. The age groups with the highest risk of being infected with HIV are 20-24 and 40-44. The most frequent way of infection is heterosexual intercourse (46%), followed by intravenous drug use (31%), whilst 23% of the registered were infected through homosexual intercourse. Out of 43 diagnosed AIDS cases, 42% are heterosexuals, 35% intravenous drug users, whilst 21 % are homosexual or bisexual. Out of the total number of registered HIV/AIDS cases in the Federation of Bosnia and Herzegovina, thirty two died during the mentioned period (54%).


2011 ◽  
Vol 19 (03) ◽  
pp. 447-460 ◽  
Author(s):  
C. P. BHUNU ◽  
S. MUSHAYABASA

A mathematical model for the transmission dynamics of Hepatitis C virus (HCV) have been proposed and investigated. The model presented looks into preferential sexual contacts between intravenous drug users and non-drug users. The threshold parameters of the model are determined and stabilities analysed. Both analytic and numerical simulations show that increase in intravenous drug use in addition to sex results in an increase of HCV cases. Thus, safe sex and treatment of HCV alone are not enough to curtail the transmission of HCV. Effective control of HCV require strategies that are tailor made for intravenous drug users.


AIDS Care ◽  
1995 ◽  
Vol 7 (3) ◽  
pp. 307-320 ◽  
Author(s):  
D. Johnston ◽  
R. Stall ◽  
K. Smith

2019 ◽  
Vol 57 (217) ◽  
Author(s):  
Lokesh Shekher Jaiswal ◽  
Narendra Pandit ◽  
Shailesh Adhikary

Introduction: Management of pseudoaneurysms in intravenous drug users is complex andchallenging due to an associated infection and unavailability of autologous vein grafts. Here weobserve the outcomes of ligation and local debridement as a primary modality of treatment in thissubset of patients with pseudoaneurysms. Methods: This is a descriptive cross sectional study of 15patients over a period of 4 years whopresented with pseudoaneurysm of peripheral artery from intravenous drug use. In this study,we describe the presentations and management outcomes in 15 patients with peripheral arterialpseudoaneurysmfrom IV drug use. Results: The most common site involved was common femoral artery among 12 (80%) patientsfollowed by superficial femoral artery among 8 (13.3%) patients and external iliac artery in 1 (6.7%)patient. Twelve (80%) patients were having signs of infection. All patients underwent surgicalintervention which comprised of excision of pseudoaneurysm and ligation of artery withoutrevascularization among 12 (80%) patients and with revascularization with autologous venous graftamong 3 (20%) patients. There was no mortality or a major bleeding requiring re-exploration. Noneof the patients developed limb ischemia necessitating amputation.One patient with femoral arteryligation without revascularization at one year of follow up is having claudication on brisk walking.There was one saphenous vein graft thrombosis in immediate postoperative period. Conclusions: With the use of ligation without revascularization technique, there was no mortality ormajor bleeding requiring re-exploration. None of the patients developed limb ischemia necessitatingamputation so this treatment modality seems promising in treatment of pseudoaneurysms inintravenous drug users.


2018 ◽  
Vol 6 ◽  
pp. 205031211878431 ◽  
Author(s):  
Olubunmi O Olubamwo ◽  
Ifeoma N Onyeka ◽  
Alex Aregbesola ◽  
Kimmo Ronkainen ◽  
Jari Tiihonen ◽  
...  

Objective: The study examined the determinants of being hospitalized for pneumonia in a large cohort of drug users. Methods: Information of 4817 clients seeking treatment for illicit drug use was linked with the Finnish hospital discharge register to identify those who were hospitalized with main/primary diagnoses of pneumonia during 1997–2013. Cox regression models were used to examine the association between age, gender, homelessness, and route of drug administration of the primary drug at initial clinical consultation and pneumonia hospitalization. Findings were presented as adjusted hazard ratios and 95% confidence intervals. Results: There were 354 persons diagnosed with pneumonia, with a total of 522 hospitalizations at the end of 2013. The univariate Cox models revealed that being over 44 years of age, male gender, homelessness, and intravenous drug use at initial clinical consultation increased the risk of being hospitalized for pneumonia. In the fully adjusted multivariate model, being over 44 years was the strongest factor independently associated with pneumonia hospitalization (adjusted hazard ratio: 2.67, 95% confidence interval: 1.56–4.57, p < 0.001), followed by homelessness (adjusted hazard ratio: 1.75, 95% confidence interval: 1.38–2.22, p < 0.001) and intravenous drug use (adjusted hazard ratio: 1.27, 95% confidence interval: 1.01–1.59, p = 0.041). Of the 354 clients hospitalized for pneumonia, 31.9% ( n = 113) were rehospitalized within 30 days of being discharged. One-third of the reasons for the 30-day rehospitalization were pneumonia-related. Conclusion: Vaccination, measures addressing housing instability, safe injecting and good hygienic practices, and treating underlying drug use problems could help to reduce morbidity for pneumonia in this cohort.


Author(s):  
Kylo-Patrick R. Hart

Representations of AIDS in film and television have differed throughout the world. Accordingly, this article focuses primarily on such representations in North America, with a particular emphasis on US media offerings and occasional references to related examples from other English-speaking countries. In the early 1980s, what eventually became known as AIDS (acquired immune deficiency syndrome) was initially labeled GRID (gay-related immune deficiency). As a result, the earliest representations of AIDS in television news programs focused almost exclusively on gay men, and shortly thereafter intravenous drug users, as “guilty villains” in the emergent AIDS crisis, with a visual emphasis on emaciated individuals covered with Kaposi’s sarcoma lesions. By 1985, independent films and documentaries pertaining to AIDS started to emerge, along with the NBC network’s first made-for-television movie about AIDS, An Early Frost. In 1987, AIDS began entering the plots of various prime-time television series. Most of these offerings continued to perpetuate understandings of AIDS as a gay disease, even into the early 1990s. As the decade of the 1980s gave way to the 1990s, the phenomenon of AIDS was increasingly being regarded as two distinct yet interrelated epidemics: HIV and AIDS. Some film and television offerings began shifting their focus away from gay men and intravenous drug users with AIDS toward children with AIDS and healthy individuals with “at-risk bodies” that required ongoing protection. In 1993, Hollywood’s first all-star movie about AIDS, Philadelphia, flipped the script by foregrounding Kaposi’s sarcoma lesions to generate substantial compassion, rather than cultural contempt, for a gay man with AIDS. The film’s contents, viewed by a wider general public than preceding works, effectively challenged AIDS discrimination. During the first half of the 1990s, a small number of noteworthy AIDS metaphor movies were made and released, and self-representation in AIDS documentaries became more common. In large part due to the availability of lifesaving antiretrovirals, which resulted in a cultural shift from large numbers of individuals dying from AIDS to large numbers living with HIV, representations of HIV/AIDS in film and television decreased substantially during the second half of the 1990s and throughout the first decade of the new millennium. Since then, there has been a growing representational interest in exploring the early history of AIDS, in offerings such as How to Survive a Plague (2012), Dallas Buyers Club (2013), and The Normal Heart (2014).


Sign in / Sign up

Export Citation Format

Share Document