scholarly journals Case of Organic Disease of the Nervous System, Presenting Some Features of General Paralysis of the Insane

1913 ◽  
Vol 6 (Sect_Psych) ◽  
pp. 72-73
Author(s):  
F. Paine
Keyword(s):  
Nervous System ◽  
Organic Disease ◽  
General Paralysis

Clinical Notes on Haemorrhages in General Paralysis

1886 ◽  
Vol 31 (136) ◽  
pp. 504-507
Author(s):  
Geo. H. Savage
Keyword(s):  
Nervous System ◽  
Nervous Disease ◽  
General Paralysis ◽  
Clinical Notes ◽  
System A ◽  
General Pathology ◽  
Mental Symptoms ◽  
The One ◽  
Nutritional Changes

In so-called nervous disorders it is common to find changes occur in other of the bodily systems than the nervous. The pathology of nervous disease should be looked upon as a general pathology, and it is certain that we cannot look to the one system alone for causes of all the nervous disorders without greatly misunderstanding the whole subject. The more exact we become in limiting the causes, the more liable are we to error. We are all prepared to consider general paralysis of the insane as essentially a disease of the nervous system, a disease in which nearly every part of the nervous system may suffer sooner or later. But beside the essentially nervous symptoms which occur in the disease, we are constantly struck by the regular series of nutritional changes which occur in general paralysis, and this is so much the case that we are quite prepared to recognise as general paralysis a disorder in which any mental symptoms have been present, but have after a brief period of acuteness been followed by a state of fatness and weak-mindedness which again has been followed by a period of wasting and further mental weakness. We have here nervous symptoms related very directly with nutritional changes.

Sulfosin Therapy in Schizophrenia

1931 ◽  
Vol 77 (319) ◽  
pp. 792-803 ◽  
Author(s):  
Louis Minski
Keyword(s):  
Nervous System ◽  
General Paralysis ◽  
Schizophrenic Patients ◽  
Extended Trial

Sulfosin was first introduced by Schroeder (1) in the treatment of general paralysis and other syphilitic infections of the nervous system, and later its use was extended to the treatment of schizophrenia. He stated that the results were encouraging, and that this method of treatment was worthy of an extended trial. Loberg (2) treated 100 schizophrenic patients with sulfosin, and of these 49 had remissions in varying degrees. In a later report (3) he stated he had treated 135 patients, of whom 62 improved but only 12 had permanent remissions. Marcuse and Kallmann (4) treated 46 patients, 16 of whom were improved; Salinger (5) treated 16 patients, of whom 2 had remissions and 14 were unchanged.

Studies in Schizophrenia: II. Estimation of Serum-Cholesterol

1952 ◽  
Vol 98 (412) ◽  
pp. 466-468 ◽  
Author(s):  
H. H. Fleischhacker ◽  
F. N. Bullock
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Serum Cholesterol ◽  
List Type ◽  
Globulin Fraction ◽  
Organic Disease ◽  
Type Number ◽  
Schizophrenic Reaction ◽  
The Central Nervous System ◽  
The Brain

IN a previous paper (Bullock, Clancey and Fleischhacker, 1951) an attempt was made to separate schizophrenic reaction syndromes, due to diagnosable and often successfully treatable disease of known etiology, from idiopathic or cryptogenic schizophrenia. It was shown that the criteria of idiopathic schizophrenia are—(1)Positivey : (a) Mentally, the classical symptoms of inadequacy and inappropriateness : of thought (paralogia), of affect (parapathema), to which one may add of volition (paraboulema), usually accompanied by hallucinations, paranoid ideas, etc.(b) Physically, a slightly pathological C.S.F., due essentially to an increase of the globulin fraction.(2)Negalively : the absence of generally acknowledged organic disease of the brain, or any physical disease which is known to produce such disorders of the central nervous system or the C.S.F., as mentioned under (i).

On Irregularity of the Pupils from Central Causes, being the substance of a Paper communicated to the Psychiatrical Section of the Philosophical Association of Germany

1859 ◽  
Vol 5 (28) ◽  
pp. 286-289
Author(s):  
Reicharz ◽  
Edward Palmer
Keyword(s):  
Nervous System ◽  
The Other ◽  
Morbid Condition ◽  
General Paralysis ◽  
Special Mention ◽  
Central Organ ◽  
The One

la describing the relative sizes of unequal pupils in the diseases of the central organ of the nervous system (as in incomplete general paralysis) most observers make special mention of the dilated pupil, and, under precisely similar essential conditions, we more frequently find one pupil characterised as being larger than the other, than the converse. Were there no prejudice at the bottom of this custom, there might be nothing to advance against it; but I believe that the views on which it is founded, are, more or less, conjectural. It is apparently assumed, in the first place, that inequality of the pupils is always caused by lesion of one iris only; that dilatation of the pupil is more truly and more frequently a morbid condition, than contraction; and, finally, that dilatation is always dependent on relaxation, resulting from paralysis. The iris, with the dilatated pupil is, thus, more often pointed out as being affected, and that with paralysis, than the one in which the pupil is contracted; and we find, moreover, that it is quite usual to adduce, not perhaps, mere inequality, but dilatation of the pupils generally, as an absolute sign and example of paralysis of single muscles.

3. ætiology of Insanity

1902 ◽  
Vol 48 (203) ◽  
pp. 775-776
Author(s):  
W. C. Sullivan
Keyword(s):  
Nervous System ◽  
Nerve Cell ◽  
Chemical Change ◽  
Mental Work ◽  
Waste Products ◽  
General Paralysis

This paper is chiefly concerned with the ætiology of general paralysis. Bianchi reaffirms his well-known views that syphilis is not the only, or even the most important factor in the genesis of the disease. It is a dystrophic malady of the nervous system, due to the accumulation in the nerve-cell of the waste products of its own activity. The syphilitic poison is one of many causes which can produce this bio-chemical change in the cell; alcoholism, arthritism, neuropathic heredity, sexual excess, are other and not less important agents. As a rule, in any given case several of these causes co-operate. They create the predisposition; any over-strain of the nerve-cell—mental work, worry, excess—develops the disease.

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