scholarly journals Submandibular Salivary Gland Tumors: Clinical Course and Outcome of a 20-Year Multicenter Study

2017 ◽  
Vol 96 (3) ◽  
pp. E17-E20 ◽  
Author(s):  
Aviram Mizrachi ◽  
Gideon Bachar ◽  
Yaron Unger ◽  
Ohad Hilly ◽  
Dan M. Fliss ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Submandibular Gland ◽  
Pleomorphic Adenoma ◽  
Clinical Course ◽  
Salivary Gland Tumor ◽  
Disease Free Survival ◽  
Retrospective Chart Review ◽  
Benign Neoplasm ◽  
Submandibular Salivary Gland ◽  
Related Data

The purpose of this retrospective chart review study was to review the nature and clinical course of benign and malignant submandibular gland tumors at 2 major university-affiliated tertiary medical centers. All patients who underwent submandibular salivary gland excision between 1990 and 2010 were included. Clinical and disease-related data were collected from the medical charts. One hundred ninety-three patients were identified, of whom 108 (56%) had non-neoplastic disorders (sialolithiasis and sialadenitis). The remaining 85 patients (44%) had a submandibular salivary gland tumor. The most common benign neoplasm was pleomorphic adenoma (53 patients). Twenty tumors (24%) were malignant: adenoid cystic carcinoma in 11 patients, mucoepidermoid carcinoma in 6 patients, and adenocarcinoma in 3 patients. Recurrence was noted in 7 patients with submandibular gland malignancy and in 2 patients with pleomorphic adenoma. The 5-year disease-free survival rate was 63%. Tumors of the submandibular gland are infrequently malignant. Recurrent submandibular salivary gland pleomorphic adenoma is rare compared with recurrences in the parotid gland.

scholarly journals Giant pleomorphic adenoma of submandibular salivary gland: a case report

2019 ◽  
Vol 7 (10) ◽  
pp. 3910
Author(s):  
Nazia T. Sheikh ◽  
Rahil Muzaffar ◽  
Sumat UL Khurshid
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumor ◽  
Submandibular Salivary Gland ◽  
Airway Compromise ◽  
Gland Tumor ◽  
Facial Disfigurement ◽  
The Right

The most common benign salivary gland tumor is the pleomorphic adenoma (PA). They can attain grotesque proportions and weigh several kilograms. They can cause facial disfigurement and, if untreated, could lead to airway compromise. Authors report a case of a large PA arising from the right submandibular salivary gland in a 48-year-old male. The lesion measured 9cmx8cmx5cm.

scholarly journals A Giant Pleomorphic Adenoma of the Submandibular Salivary Gland: A Case Report

2012 ◽  
Vol 5 (3) ◽  
pp. 185-188 ◽  
Author(s):  
Colin J. Perumal ◽  
Mark Meyer ◽  
Ashraf Mohamed
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumor ◽  
Black Female ◽  
Submandibular Salivary Gland ◽  
Airway Compromise ◽  
Gland Tumor ◽  
Facial Disfigurement

The most common benign salivary gland tumor is the pleomorphic adenoma (PA). They can attain grotesque proportions and weigh several kilograms. They can cause facial disfigurement and, if untreated, could lead to airway compromise. We report a case of a large PA arising from the left submandibular salivary gland in a 20-year-old black female. The lesion measured ∼16 × 15 ×12 cm.

scholarly journals Pleomorphic adenoma of submandibular gland: not so common occurrence

2018 ◽  
Vol 5 (2) ◽  
pp. 657
Author(s):  
Ashok S. Gajbhiye ◽  
Mukteshwar N. Deshmukh ◽  
Parag K. Jaipuriya ◽  
Kishor B. Jeughale ◽  
Abhinav A. Kumar ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Submandibular Gland ◽  
Pleomorphic Adenoma ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Submandibular Salivary Gland ◽  
Radical Excision ◽  
Submandibular Region ◽  
Female Ratio

Background: The salivary glands tumour are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes. Several studies have been conducted on the tumors of the parotid and minor salivary glands, but very few reports in the literature have focused on submandibular gland tumors as they are rare and are usually grouped with other salivary glands. Approximately 70% of the salivary gland tumors affect parotid gland with the submandibular gland being affected in 5-10% of the cases, sublingual gland in 1% and minor glands in 5-15% of the cases. So, we describe a series of 50 patients of pleomorphic adenoma affecting submandibular gland.Methods: The prospective study was conducted at Department of General Surgery, Indira Gandhi Government Medical College, Nagpur between January 2008 to December 2017.Results: Out of the 50 patients, 10 were male and 40 were female. Thus, male to female ratio is 1:4. Most of the 42 (84%) patients presented with painless swelling in submandibular region. Clinically the tumour has the texture of cartilage and has an irregular and bosselated surface observed in all the patients. The size of tumour was 3 to 6 cm in 32 (64%) patients observed in the present study. Fine needle aspiration cytology was performed in all the patients. All patients were managed by surgical excision.  Recurrence occurred in a single patient who was managed with radical excision including a neck dissection with postoperative radiotherapy.Conclusions: Submandibular gland pleomorphic adenoma being common benign tumor, occurring commonly between the 3rd and 5th decade of life and presenting as slow growing asymptomatic swelling with female preponderance. The precise surgical excision along with whole submandibular salivary gland and postoperative radical radiotherapy required for recurrence as the accepted mode of management. However, further long-term studies involving submandibular gland have to be carried out to know the pattern of tumor recurrence.

scholarly journals Primary Salivary Gland Tumors- A two years study at Nobel Medical College

2019 ◽  
Vol 2 (2) ◽  
pp. 234-238
Author(s):  
Niraj Nepal ◽  
Prabesh Kumar Choudhary ◽  
Manish Kumar Das ◽  
Meenakshi Basnet ◽  
Sagar Paudel
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Malignant Tumors ◽  
Age Groups ◽  
Salivary Gland Tumor ◽  
Salivary Gland Tumors ◽  
Parotid Glands ◽  
Gland Tumor ◽  
Medical College

Introduction: Salivary gland tumors are a heterogeneous group of neoplasms that are relatively rare but represent a wide variety of both benign and malignant histopathologic subtypes. The aim of this study was to find out the histopathological distribution of primary salivary gland tumors and correlate fine needle aspiration cytology reports with histological findings.Materials and Methods: A total of 83 patients attending the otorhinolaryngology department with salivary gland tumors were enrolled in our study. The histopathological findings were reported and correlated with cytological findings.Results: The mean age of the patient with salivary tumors was 43.11 ± 13.02 years. Out of 83 cases, 3 (3.6%) patients were diagnosed as inflammatory lesions, 64 (77.1%) patients had benign salivary gland tumors and 16 (19.3%) of patients had malignant salivary glands tumors in histopathology. The sensitivity and specificity of FNAC in this series for detecting salivary gland malignancy were 68.8% and 98.5% respectively with an overall diagnostic accuracy of 92.8%. The most common salivary gland tumor was found to be pleomorphic adenoma (56.6%) and the most common malignant salivary gland tumor was found to be mucoepidermoid carcinoma (19.3%). The comparison of the incidence of salivary gland tumors in various age groups showed a statisticallysignificant difference (p=0.009).  Conclusions: Benign salivary tumors are more common than malignant tumors with the most common occurrence in parotid glands. Pleomorphic adenoma is the most common benign tumor whereas; mucoepidermoid carcinoma is the most common malignant tumor in patients visiting Nobel medical college.

A massive pleomorphic adenoma of the submandibular salivary gland

1997 ◽  
Vol 55 (9) ◽  
pp. 1011-1014 ◽  
Author(s):  
Behçet Erol ◽  
Nedim Özer ◽  
Gülten Unlü ◽  
Belgin Gülsün
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Submandibular Salivary Gland

scholarly journals Myoepithelial Cell-Rich Pleormorphic Adenoma of Minor Salivary Gland of Parapharyngeal Space

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Digvijay Singh Rawat ◽  
Divij Sonkhya ◽  
Nishi Sonkhya ◽  
Shubha Gupta
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Myoepithelial Cell ◽  
Parapharyngeal Space ◽  
Histopathological Examination ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumor ◽  
Neck Tumors ◽  
S 100 ◽  
Fibrous Tumor

Parapharyngeal space tumors are rare and constitute only 0.5–1.0% of head and neck tumors. Minor salivary gland tumor is still rare in parapharyngeal space. We are reporting a case of pleomorphic adenoma of minor salivary gland of parapharyngeal space. A 42-year-old female presented with a history of mass in the oropharynx for 3 years. She presented with “hot potato voice” and dysphagia. CECT and MRI were done, showing large parapharyngeal space tumor. FNAC was suspicious for tumor of nerve cell origin. Tumor was excised using “paramedian mandibulotomy with mandibular swing approach”. Histopathological examination was inconclusive, suggesting possibility of extraskeletal myxoid chondrosarcoma, solitary fibrous tumor, neurogenic tumor. On immunohistochemistry, tumor was positive for cytokeratin, EMA (dim), S-100, and P 63 and negative for SMA thus proving the case as myoepithelial cell-rich pleomorphic adenoma.

Sialolithiasis in a residual Wharton's duct after excision of a submandibular salivary gland

2006 ◽  
Vol 121 (2) ◽  
pp. 182-185 ◽  
Author(s):  
M R Markiewicz ◽  
J E Margarone 3rd ◽  
J L Tapia ◽  
A Aguirre
Keyword(s):  
Salivary Gland ◽  
Submandibular Gland ◽  
Acute Infection ◽  
Surgical Techniques ◽  
Surgical Approaches ◽  
Submandibular Salivary Gland ◽  
Major Salivary Gland ◽  
Continuous Growth ◽  
Wharton’S Duct ◽  
Submandibular Gland Excision

Treatment of salivary stones includes both surgical and non-surgical techniques. Surgical approaches range from excision of the sialolith, for those near the duct orifice, to removal of the affected salivary gland and its associated duct, for stones near the hilum of the gland. We present a case of two sialoliths triggering an acute infection in a residual Wharton's duct, 12 years after the removal of the associated submandibular gland. Excision of the sialoliths and treatment of the infected duct via sialodochoplasty was successfully performed in this patient. If the Wharton's duct is not removed with the associated submandibular gland, the potential for infection and continuous growth of dormant calcifications exists. We also address the aetiology, pathogenesis, and management of patients with sialolithiasis in the absence of a major salivary gland.

scholarly journals Unusual Variations in Path of Accessory Submandibular Salivary Gland Duct in Comparison with Main Submandibular Salivary Gland Duct

2018 ◽  
Vol 26 (2) ◽  
Author(s):  
Anita Anita ◽  
Saryu Sain ◽  
Amrita Gupta
Keyword(s):  
Salivary Gland ◽  
Submandibular Gland ◽  
Submandibular Salivary Gland ◽  
Main Duct ◽  
Mylohyoid Muscle ◽  
Lower Incisor ◽  
Submandibular Region ◽  
Submandibular Duct ◽  
Gland Duct ◽  
Wharton’S Duct

Introduction: The submandibular gland is located bilaterally in the submandibular triangle. The main submandibular duct or Wharton’s duct, runs with lingual nerve to open in the sublingual papilla at the side of frenulum of the tongue. The aim of this study was to demonstrate the unusual variations of accessory submandibular duct in comparison with main submandibular salivary gland duct. Material & Methods: Nineteen cadavers were dissected to study the submandibular salivary duct. Results: 15.7% incidence of variations were observed. We found that one submandibular region was having unusual path of accessory duct, it emerged from superficial part of the gland and crossed the superficial surface of mylohyoid muscle and bifurcated into two branches. These bifurcated branches of duct pierced the mylohyoid muscle to pass between mylohyoid and hyoglossus muscle. One branch of bifurcated accessory duct opened through papilla in the floor of the mouth behind the lower incisor tooth and second branch of the bifurcated duct anastomosed with the main duct (Wharton’s duct) to open in sublingual papilla. Wharton’s duct of this side followed its normal path to open in the sublingual papilla. Two specimens of submandibular region was observed with duplication of submandibular duct in each submandibular gland. One was main duct and second was accessory duct. Both ducts emerged separately from the deep part of submandibular gland and ended independently into sublingual papilla. Conclusion: Reporting of these variations are important for diagnostic imaging, anatomical teaching and to help surgeons while operating in this region.

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