scholarly journals Pleomorphic adenoma of submandibular gland: not so common occurrence

2018 ◽  
Vol 5 (2) ◽  
pp. 657
Author(s):  
Ashok S. Gajbhiye ◽  
Mukteshwar N. Deshmukh ◽  
Parag K. Jaipuriya ◽  
Kishor B. Jeughale ◽  
Abhinav A. Kumar ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Submandibular Gland ◽  
Pleomorphic Adenoma ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Submandibular Salivary Gland ◽  
Radical Excision ◽  
Submandibular Region ◽  
Female Ratio

Background: The salivary glands tumour are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes. Several studies have been conducted on the tumors of the parotid and minor salivary glands, but very few reports in the literature have focused on submandibular gland tumors as they are rare and are usually grouped with other salivary glands. Approximately 70% of the salivary gland tumors affect parotid gland with the submandibular gland being affected in 5-10% of the cases, sublingual gland in 1% and minor glands in 5-15% of the cases. So, we describe a series of 50 patients of pleomorphic adenoma affecting submandibular gland.Methods: The prospective study was conducted at Department of General Surgery, Indira Gandhi Government Medical College, Nagpur between January 2008 to December 2017.Results: Out of the 50 patients, 10 were male and 40 were female. Thus, male to female ratio is 1:4. Most of the 42 (84%) patients presented with painless swelling in submandibular region. Clinically the tumour has the texture of cartilage and has an irregular and bosselated surface observed in all the patients. The size of tumour was 3 to 6 cm in 32 (64%) patients observed in the present study. Fine needle aspiration cytology was performed in all the patients. All patients were managed by surgical excision.  Recurrence occurred in a single patient who was managed with radical excision including a neck dissection with postoperative radiotherapy.Conclusions: Submandibular gland pleomorphic adenoma being common benign tumor, occurring commonly between the 3rd and 5th decade of life and presenting as slow growing asymptomatic swelling with female preponderance. The precise surgical excision along with whole submandibular salivary gland and postoperative radical radiotherapy required for recurrence as the accepted mode of management. However, further long-term studies involving submandibular gland have to be carried out to know the pattern of tumor recurrence.

scholarly journals Uncommon occurrence of pleomorphic adenoma in submandibular salivary gland in old age males: case series

2020 ◽  
Vol 7 (3) ◽  
pp. 900
Author(s):  
M. S. Kalyan Kumar ◽  
R. Shyamsundar ◽  
M. Sabari Girieasen ◽  
R. Kannan ◽  
S. Nedunchezhiyan
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Benign Lesion ◽  
Case Series ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Submandibular Salivary Gland ◽  
Biopsy Report ◽  
Needle Aspiration Cytology

Pleomorphic adenoma is the most common tumor of the benign salivary gland neoplasms, the submandibular gland is the second most common site of PA after the parotid gland. Authors present 3 series case of pleomorphic adenoma in submandibular salivary gland in institution which were admitted in institution within a month interval. Fine needle aspiration cytology (FNAC) of all 3 cases proved to be benign lesion arising from submandibular salivary gland. All 3 cases underwent excision in to and the postoperative period was uneventful. DT removed on 3rd POD and discharged in POD 10. Biopsy report proved to be pleomorphic adenoma in all cases. past studies showed pleomorphic adenoma most commonly occurs in the parotid gland and its occurrence in the submandibular salivary gland is uncommon. Also, age occurrence involves 30s-50s and is more common in females. But all this case was male and occurred in older age group. Early intervention with surgical excision in toto after definite confirmation with FNAC is the treatment of choice in preventing its malignant transformation.

scholarly journals An unusual pleomorphic adenoma

2014 ◽  
Vol 62 (3) ◽  
pp. 319-324
Author(s):  
Christiano Sampaio QUEIROZ ◽  
Roberto Almeida de AZEVEDO ◽  
Antonio Irineu TRINDADE NETO ◽  
Caetano Guilherme Carvalho PONTES ◽  
Rafael de Queiroz MOURA
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Histopathological Examination ◽  
Minor Salivary Gland ◽  
Surgical Excision ◽  
Biological Behavior ◽  
Surgical Removal ◽  
Minor Salivary Glands ◽  
Recommended Treatment

Pleomorphic adenoma is the most common neoplasm in major and minor salivary glands. It constitutes approximately 90% of all benign salivary gland lesions and the parotid is the most affected location. When the minor salivary glands are affected, it mostly occurs at the junction of the hard and soft palates. The diagnosis is complex because of the great histological variety and biological behavior of this tumor, a histopathological examination being essential. The recommended treatment is surgical excision. For lesions located superficially in the parotid gland, superficial parotidectomy - identifying and preserving the facial nerve - is necessary. Lesions in the palate or gums sometimes demand a margin of safety, being excised below the periosteum, including the overlying mucosa. With correct surgical removal, the prognosis is excellent. The aim of this study is to report a case of an unusual minor salivary gland pleomorphic adenoma in the hard palate, describing the most important aspects of this pathology.

scholarly journals Unusual Variations in Path of Accessory Submandibular Salivary Gland Duct in Comparison with Main Submandibular Salivary Gland Duct

2018 ◽  
Vol 26 (2) ◽  
Author(s):  
Anita Anita ◽  
Saryu Sain ◽  
Amrita Gupta
Keyword(s):  
Salivary Gland ◽  
Submandibular Gland ◽  
Submandibular Salivary Gland ◽  
Main Duct ◽  
Mylohyoid Muscle ◽  
Lower Incisor ◽  
Submandibular Region ◽  
Submandibular Duct ◽  
Gland Duct ◽  
Wharton’S Duct

Introduction: The submandibular gland is located bilaterally in the submandibular triangle. The main submandibular duct or Wharton’s duct, runs with lingual nerve to open in the sublingual papilla at the side of frenulum of the tongue. The aim of this study was to demonstrate the unusual variations of accessory submandibular duct in comparison with main submandibular salivary gland duct. Material & Methods: Nineteen cadavers were dissected to study the submandibular salivary duct. Results: 15.7% incidence of variations were observed. We found that one submandibular region was having unusual path of accessory duct, it emerged from superficial part of the gland and crossed the superficial surface of mylohyoid muscle and bifurcated into two branches. These bifurcated branches of duct pierced the mylohyoid muscle to pass between mylohyoid and hyoglossus muscle. One branch of bifurcated accessory duct opened through papilla in the floor of the mouth behind the lower incisor tooth and second branch of the bifurcated duct anastomosed with the main duct (Wharton’s duct) to open in sublingual papilla. Wharton’s duct of this side followed its normal path to open in the sublingual papilla. Two specimens of submandibular region was observed with duplication of submandibular duct in each submandibular gland. One was main duct and second was accessory duct. Both ducts emerged separately from the deep part of submandibular gland and ended independently into sublingual papilla. Conclusion: Reporting of these variations are important for diagnostic imaging, anatomical teaching and to help surgeons while operating in this region.

Hypoglossal schwannoma in the submandibular region

2021 ◽  
Vol 14 (5) ◽  
pp. e242225
Author(s):  
Aparna Das ◽  
Sivaraman Ganesan ◽  
Kalaiarasi Raja ◽  
Arun Alexander
Keyword(s):  
Salivary Gland ◽  
Submandibular Gland ◽  
Hypoglossal Nerve ◽  
Malignant Lesion ◽  
Submandibular Salivary Gland ◽  
Submandibular Region ◽  
Imaging Characteristics ◽  
Contrast Enhanced Ct ◽  
The Right ◽  
Hypoglossal Schwannoma

Hypoglossal nerve schwannomas originating extracranially and mimicking a submandibular salivary gland tumour are extremely rare. A 55-year-old woman presented with a painless, gradually increasing swelling in the right submandibular region for the past 1 year. Fine-needle aspiration cytology and contrast-enhanced CT of the swelling showed features of submandibular gland malignant lesion. Intraoperatively, the right submandibular gland with a hypoglossal nerve swelling was noticed. Right submandibular gland along with the hypoglossal swelling were excised with adequate margins. However, the postoperative histopathology was reported as hypoglossal nerve schwannoma and a normal salivary gland. Accurate preoperative diagnosis of hypoglossal schwannomas may be challenging. A high level of suspicion must be sought for in cases with unusual clinical presentations and imaging characteristics. Herein, we report a rare presentation of submandibular hypoglossal schwannoma along with its clinical features and its management.

Submandibular salivary gland tumors: a clinicopathologic review of 58 cases

2018 ◽  
Vol 7 (1) ◽  
pp. 54-58
Author(s):  
Marcin Jarosław Kubiak ◽  
Dariusz Kaczmarczyk ◽  
Aleksandra Oleśna ◽  
Alina Morawiec-Sztandera
Keyword(s):  
Salivary Gland ◽  
Submandibular Gland ◽  
Pleomorphic Adenoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Salivary Gland Tumors ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Objectives: Salivary gland tumors account for only 3% of head and neck tumors. Their character is mostly benign, although tumors of the submandibular gland are more often malignant. The purpose of this article was to evaluate the structure of patients operated due to submandibular gland tumor and to study the correlation between fine-needle aspiration cytology and postoperative histopathological examination. Methodology: We retrospectively analyzed the medical records of all patients with submandibular gland tumors. The collected data included the demographic structure, results of preoperative fine-needle aspiration cytology and postoperative histopathologic examination. Results: We analyzed 58 patients – 35 women and 23 men with a mean age of 56.6 years. The character of the lesion was benign in 45 cases and malignant in 13. The most frequent benign tumors were pleomorphic adenoma, inflammatory tumor and Warthin’s tumor, whereas most common malignancies were carcinoma planoepitheliale and lymphoma . There were four recurrences. Moreover, we compared results of preoperative fine-needle aspiration cytology and histopathological findings. The accuracy of this examination was almost 83%; 56% of incorrect results involved nondetection of malignancies. The sensitivity and specificity in the diagnosis of those tumors were 58.3% and 97.5%, respectively. Conclusions: The most common types of submandibular gland are pleomorphic adenoma and carcinoma planoepitheliale and lymphoma amongst malignancies. Fine-needle aspiration cytology is accurate in the preoperative diagnosis, mistakes are mostly caused by underdiagnosis of malignant tumors.

scholarly journals Submandibular Salivary Gland Tumors: Clinical Course and Outcome of a 20-Year Multicenter Study

2017 ◽  
Vol 96 (3) ◽  
pp. E17-E20 ◽  
Author(s):  
Aviram Mizrachi ◽  
Gideon Bachar ◽  
Yaron Unger ◽  
Ohad Hilly ◽  
Dan M. Fliss ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Submandibular Gland ◽  
Pleomorphic Adenoma ◽  
Clinical Course ◽  
Salivary Gland Tumor ◽  
Disease Free Survival ◽  
Retrospective Chart Review ◽  
Benign Neoplasm ◽  
Submandibular Salivary Gland ◽  
Related Data

The purpose of this retrospective chart review study was to review the nature and clinical course of benign and malignant submandibular gland tumors at 2 major university-affiliated tertiary medical centers. All patients who underwent submandibular salivary gland excision between 1990 and 2010 were included. Clinical and disease-related data were collected from the medical charts. One hundred ninety-three patients were identified, of whom 108 (56%) had non-neoplastic disorders (sialolithiasis and sialadenitis). The remaining 85 patients (44%) had a submandibular salivary gland tumor. The most common benign neoplasm was pleomorphic adenoma (53 patients). Twenty tumors (24%) were malignant: adenoid cystic carcinoma in 11 patients, mucoepidermoid carcinoma in 6 patients, and adenocarcinoma in 3 patients. Recurrence was noted in 7 patients with submandibular gland malignancy and in 2 patients with pleomorphic adenoma. The 5-year disease-free survival rate was 63%. Tumors of the submandibular gland are infrequently malignant. Recurrent submandibular salivary gland pleomorphic adenoma is rare compared with recurrences in the parotid gland.

scholarly journals A comparative study between fine needle aspiration cytology findings and histopathological report of major salivary gland neoplasm in a tertiary hospital of Bangladesh

2014 ◽  
Vol 39 (2) ◽  
pp. 69-73 ◽  
Author(s):  
AHMZ Huq ◽  
M Aktaruzzaman ◽  
MA Habib ◽  
MS Islam ◽  
ASA Amin
Keyword(s):  
Salivary Gland ◽  
Submandibular Gland ◽  
False Negative ◽  
Needle Aspiration ◽  
Salivary Gland Neoplasm ◽  
Major Salivary Gland ◽  
Female Ratio ◽  
Parotid Tumour ◽  
Negative Results ◽  
Needle Aspiration Cytology

Salivary gland tumours are relatively uncommon and most of the tumours arise from parotid gland. Fine needle aspiration cytology (FNAC) is advised preoperatively as diagnostic tool but sometimes found to shown both false positive and false negative results. This study was aimed to find out distribution of neoplasm of major salivary glands and also to explore the sensitivity and specificity of FNAC. The present cross sectional study was done in the Dept. of Otolaryngology Head and Neck Surgery, BSMMU from January 2007 to December 2008. A total number of 60 gender-matched patients with major salivary neoplasm, confirmed by FNAC, were recruited in the study. Operated salivary gland specimens were sent for histopathological examination, histopathological findings were compared. Overall male to female ratio was 1:1. Out of 60 cases, 47 (78.3%) patients had parotid and 13 (21.7%) patients submandibular gland neoplasm. Male to female ratio for parotid tumour was1:1.1 and for submandibular 1.6:1. Mean age of the patients was 44.5 with range of 14-85 years. Of the total 60 cases 47 (78.3%) were benign and 13 (21.7%) malignant. Out of 47 parotid tumour 85.1% were benign and 14.9% malignant. Among the parotid tumour 97% were superficial lobe and 3.0% deep lobe. In case of submandibular gland 53.84% were benign and 46.15% tumour malignant. According to the sides of involvement, 25 (53.2%) cases of parotid neoplasm tumour were in the left and 22(46.8%) the right. In submandibular gland the distribution was 7 (53.8%) and 6 (46.16%) respectively. Statistically incidence of parotid tumour was significantly higher than submandibular tumour (p<0.05). Out of 60 cases in 56 (93.3%) preoperative FNAC and postoperative histopathological findings were same. There was 1.7% false positive and 5% were false negative results. Sensitivity, specificity of FNAC were 80% and 97.8% respectively. Positive predictive value was 92.3% and negative predictive 93.6% for FNAC.FNAC though cheap and safe but its diagnostic accuracy was 93.3%.Histopathologial examination remained to be of value for diagnostic confirmation of major salivary gland neoplasm. DOI: http://dx.doi.org/10.3329/bmrcb.v39i2.19645 Bangladesh Med Res Counc Bull 2013; 39: 69-73

scholarly journals An Uncommon Occurrence of Pleomorphic Adenoma in the Submandibular Salivary Gland: A Case Report

2018 ◽  
Vol 6 (6) ◽  
pp. 1101-1103
Author(s):  
Farhat Farhat ◽  
Rizalina A. Asnir ◽  
Ashri Yudhistira ◽  
Elvita Rahmi Daulay ◽  
Irwan Pernandi Sagala
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Surgical Excision ◽  
Malignant Tumour ◽  
Submandibular Salivary Gland ◽  
Soft Tissue Tumour ◽  
Mixed Tumour ◽  
Best Management ◽  
Tissue Tumour ◽  
Left Neck

BACKGROUND: Pleomorphic adenoma is a salivary gland tumour and mostly found in the parotid gland and quite uncommon in the submandibular gland. Pleomorphic tumours are a mixed tumour (benign mixed tumour) consisted of epithelium, myoepithelium, and mesenchyme and made of a view component variation of it.CASE REPORT: We reported a fifty-three years old man with pleomorphic adenoma that has been complaining swelling on the left neck for the last twenty years and treated with surgical excision. Computed tomography of the neck showed soft tissue tumour in the left submandibular.CONCLUSIONS: The best management for pleomorphic adenoma is surgery, the tumour tissue must be removed as a whole because the remaining parts of a tumour can easily become recurrent or turn into a malignant tumour.

Pleomorphic Adenoma of Buccal Mucosa: A Rare Clinical Entity

2020 ◽  
Author(s):  
Sooraj Somah
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Buccal Mucosa ◽  
Histopathological Examination ◽  
Imaging Techniques ◽  
Salivary Gland Tumor ◽  
Neck Region ◽  
Surgical Excision ◽  
Minor Salivary Glands

Salivary gland tumors are rare tumors in the head and neck region and Pleomorphic Adenoma (PA) is the commonest salivary gland tumor. It is a benign tumor usually affecting parotid, submandibular or minor salivary glands. In minor salivary glands, the palate and lip are the commonest sites. Histopathological examination and various imaging techniques aid n diagnosis. Wide surgical excision is the treatment of choice. Here we present a rare case of PA of the buccal mucosa.

scholarly journals Milan system in salivary gland lesions: Its diagnostic and clinical relevance

2021 ◽  
Vol 12 (11) ◽  
pp. 45-52
Author(s):  
Smriti Singh ◽  
Parveen Rana ◽  
Swaran Kaur ◽  
Uma Garg ◽  
Deepti Agarwal ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Statistical Analysis ◽  
Standard Deviation ◽  
Pleomorphic Adenoma ◽  
Quantitative Data ◽  
Surgical Excision ◽  
Analysis Data ◽  
Needle Aspiration ◽  
Salivary Gland Neoplasm ◽  
Common Benign Tumor

Background: The salivary gland lesions constitute around 3–6% of all head-and-neck lesions and have always posed a diagnostic riddle for the cytopathologists around the world. Since the majority of these lesions need surgical excision, it is, therefore, important to diagnose these lesions with utmost precision to prevent over or under stage procedures. The recent adaption of Milan system of reporting aims to establish a uniform, accurate, and consensual reporting system which bridges the communication between the pathologists and the clinicians. Aims and Objectives: The current study aims to assess the diagnostic application of Milan system and aims to reclassify the lesions according to it. Materials and Methods: The current study was conducted at our institute during 1 year period. All salivary gland swellings presenting to the fine-needle aspiration cytology (FNAC) section during this period were included in the study. Along with this, records and slides of cases of salivary gland lesions were retrospectively assessed. All relevant data and radiologic findings were retrieved from the case records. FNAC was done using 23 G needle. The slides were stained with both Leishman and Papanicolaou stain wherever possible. Quantitative data were expressed as mean and standard deviation and percentages. All the 83 lesions were reclassified as per the Milan system. Histopathology was available in 42 cases. Inclusion criteria: All the samples of the patient having salivary gland lesion(s) whose FNAC were performed in the department of pathology. Statistical Analysis: Data were be entered into Microsoft Excel spreadsheets. For quantitative data, mean and standard deviation were calculated. For qualitative data, percentage and proportion were calculated. Sensitivity, specificity, and spearman correlation between FNAC and histopathology were calculated. P<0.05 was considered statistically significant. Results: The total of 83 cases was included in our study. The cytological analysis was done and all cases were classified as per Milan system. The age of patients ranged from 4 years to 77 years with a mean age of 43 years. Parotid was the most frequently involved gland in which a total of 51 cases (61.4%) were reported. The most common benign tumor reported on cytology was pleomorphic adenoma and the most common malignant tumor reported was adenoid cystic carcinoma. On recategorization of lesions as per Milan system, the category IVA, that is, benign salivary gland neoplasm had the maximum number of lesions (40) accounting for 48.1% of all the lesions. Histopathology was available in 42 cases. The predominant lesion on histopathology was pleomorphic adenoma (22). On statistical analysis of the data, the sensitivity was 71.4%, specificity was 96.1%, diagnostic accuracy as 62.1%, and positive and negative predictive value as 83.3 and 92.5%, respectively. Conclusion: Risk stratification approach in classifying salivary gland cytology aspirate as per Milan system provides a standardized reporting and better communication to clinician.

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