scholarly journals Analyses of High-Risk Factors for Cervical Lymph Node Metastasis in Laryngeal Squamous Cell Carcinoma and Establishment of Nomogram Prediction Model

2020 ◽  
pp. 014556132090161
Author(s):  
Lu-ying Chen ◽  
Wei-bin Weng ◽  
Wen Wang ◽  
Jian-fu Chen
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Predictive Performance ◽  
Cervical Lymph Node Metastasis ◽  
Node Metastasis

Laryngeal squamous cell carcinoma (LSCC) is one of the most common laryngeal tumors, and its incidence is increasing yearly; however, whether lymph node dissection should be performed during surgery remains unclear. We retrospectively analyzed the clinical and pathological data of 246 cases of LSCC and developed a nomogram for the prediction of lymph node metastasis (LNM) of LSCC. The predictive performance and consistency of the model were evaluated using the consistency coefficient (C-index) and calibration curve, respectively. Among 246 cases of LSCC, 52 cases had metastasis with a positivity rate of 21.14%. Multivariate analyses showed that dysphagia, clinical T stage, and pathological differentiation were independent risk factors for LNM in LSCC. The accuracy of the contour map used to predict the risk for LNM was 0.809. Overall, this nomogram model can be used to evaluate LNM in patients with LSCC before surgery to decide whether to conduct neck dissection and improve patient prognosis.

scholarly journals A nomogram to predict lymph node metastasis risk for early esophageal squamous cell carcinoma

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaofeng Duan ◽  
Xiaobin Shang ◽  
Jie Yue ◽  
Zhao Ma ◽  
Chuangui Chen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Derivation Cohort ◽  
Node Metastasis

Abstract Background A nomogram was developed to predict lymph node metastasis (LNM) for patients with early-stage esophageal squamous cell carcinoma (ESCC). Methods We used the clinical data of ESCC patients with pathological T1 stage disease who underwent surgery from January 2011 to June 2018 to develop a nomogram model. Multivariable logistic regression was used to confirm the risk factors for variable selection. The risk of LNM was stratified based on the nomogram model. The nomogram was validated by an independent cohort which included early ESCC patients underwent esophagectomy between July 2018 and December 2019. Results Of the 223 patients, 36 (16.1%) patients had LNM. The following three variables were confirmed as LNM risk factors and were included in the nomogram model: tumor differentiation (odds ratio [OR] = 3.776, 95% confidence interval [CI] 1.515–9.360, p = 0.004), depth of tumor invasion (OR = 3.124, 95% CI 1.146–8.511, p = 0.026), and tumor size (OR = 2.420, 95% CI 1.070–5.473, p = 0.034). The C-index was 0.810 (95% CI 0.742–0.895) in the derivation cohort (223 patients) and 0.830 (95% CI 0.763–0.902) in the validation cohort (80 patients). Conclusions A validated nomogram can predict the risk of LNM via risk stratification. It could be used to assist in the decision-making process to determine which patients should undergo esophagectomy and for which patients with a low risk of LNM, curative endoscopic resection would be sufficient.

Risk factors of lymph node metastasis in T1 esophageal squamous cell carcinoma

2008 ◽  
Vol 23 (4) ◽  
pp. 619-625 ◽  
Author(s):  
Dong Uk Kim ◽  
Jun Haeng Lee ◽  
Byung-Hoon Min ◽  
Sang Goon Shim ◽  
Dong Kyung Chang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Node Metastasis

scholarly journals Association of Anneroth’s Scoring and Frequency of Cervical Lymph Node Metastasis among Primary Oral Squamous Cell Carcinoma Patients

2019 ◽  
Vol 6 (2) ◽  
pp. 69-72
Author(s):  
Mohammad Ahtashamul Haque ◽  
Uday Kumar Goswami ◽  
Md Mostafijur Rahman ◽  
Mohammad Wahidul Islam ◽  
Md Mahboob Morshed ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cervical Lymph Node ◽  
Cervical Lymph Node Metastasis ◽  
Primary Lesion ◽  
Node Metastasis

Background: Primary Oral Squamous Cell Carcinoma can metastasize in the cervical lymph nodes. Objective: The purpose of the present study was to see the association of Anneroth’s scoring and frequency of cervical lymph node metastasis among primary oral squamous cell carcinoma patients. Methodology: This cross sectional study was conducted in the Department of Oral and Maxillofacial Surgery, Dhaka Dental College and Hospital, Dhaka, Bangladesh from November 2009 to December 2010 for a period of one year. Patients attending in the place of study with diagnosed case of oral squamous cell carcinoma were selected for the study after fulfilling the inclusion criteria. The resected primary lesion and neck lymph nodes were sent for histopathological examination. Histopathological grading of the primary lesion was done and neck lymphodes were graded as metastatic and non-metastatic. Results: This prospective study with 50 cases of oral squamous cell carcinoma was taken of which 28 cases were non-metastasis tumor. Each case was graded according to TNM classification, Broder’s grading and Anneroth’s classification. Both Anneroth’s classification (p=0.002) and Broder’s grading (p=0.017) were significant but Anneroth’s one was more significant than Broder’s. Conclusions: There is an association between Anneroth’s grading system with lymph node metastasis. Journal of Current and Advance Medical Research 2019;6(2): 69-72

scholarly journals Risk factors of lymph node metastasis in lung squamous cell carcinoma of 3 cm or less in diameter

Medicine ◽  
2017 ◽  
Vol 96 (29) ◽  
pp. e7563 ◽  
Author(s):  
Lijian Huang ◽  
Wenshan Li ◽  
Lufeng Zhao ◽  
Baizhou Li ◽  
Ying Chai
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lung Squamous Cell Carcinoma ◽  
Node Metastasis

Evaluation of progression level of extracapsular spread for cervical lymph node metastasis of oral squamous cell carcinoma

Toukeibu Gan ◽  
2014 ◽  
Vol 40 (4) ◽  
pp. 437-442
Author(s):  
Shin-ichi Yamada ◽  
Souichi Yanamoto ◽  
Hidenori Takahashi ◽  
Yuki Matsushita ◽  
Tomofumi Naruse ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cervical Lymph Node ◽  
Cervical Lymph Node Metastasis ◽  
Extracapsular Spread ◽  
Node Metastasis
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