A Rare Case of Prostate Carcinoma Metastasis in the Orbital Apex

Prostate cancer (PC) is prone to bone metastases, but very rarely it can spread to soft tissues. In the head and neck region, PC can metastasize to the orbital soft tissue, causing various symptoms such as vision loss. In this report, we describe the case of a 79-year-old man with PC metastasis in the orbital apex. He presented to an ophthalmologist at our hospital with progressively worsening vision in his left eye over 3 to 4 months. He complained of a drooping eyelid in the same eye; thus, intracranial disease was suspected. Closer inspection with head computed tomography revealed a space-occupying lesion from the orbit to the posterior ethmoid sinus, and he was referred to our department. He had a history of PC, and we performed endoscopic sinus surgery for the diagnosis of malignancy, including metastasis of PC. As a result, the mass was diagnosed as PC metastasis by pathological examination. The patient began androgen blockade therapy and 3 months postoperatively, magnetic resonance imaging revealed that the extraconal orbital mass had decreased significantly. It is important to determine the metastases of PC in the paranasal region when the patient has a preexisting medical history.

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Extramedullary Plasmacytoma of the Larynx Treated by a Surgical Endoscopic Approach and Radiotherapy

Case Reports in Otolaryngology ◽

10.1155/2015/951583 ◽

2015 ◽

Vol 2015 ◽

pp. 1-4

Author(s):

Massimiliano Pino ◽

Filippo Farri ◽

Pietro Garofalo ◽

Fausto Taranto ◽

Andrea Toso ◽

...

Keyword(s):

Plasma Cell ◽

Soft Tissues ◽

Neck Region ◽

Extramedullary Plasmacytoma ◽

Head And Neck Region ◽

History Of ◽

Uncommon Case ◽

Disseminated Disease ◽

Transoral Resection ◽

Suspension Laryngoscopy

Extramedullary plasmacytoma (EMP) is a rare variant of plasma cell myeloma that affects soft tissues. The head and neck region are the most affected sites, although others have also been described. Herein we report an uncommon case of EMP of the larynx in a 65-year-old male who presented with a history of progressive dysphonia and hoarseness. Laryngeal fiberscopy evidenced a reddish pedicled voluminous mass in the left false cords and ventricle. Microscopic suspension laryngoscopy was performed under general anaesthesia and a 4 W Acublade CO2 Laser was used for transoral resection of the lesion. This was followed by adjuvant radiotherapy, with the widely recommended doses on the supraglottic region, to achieve better local control. Diagnosis of EMP is based on immunohistochemistry and the exclusion of systemic plasma cell proliferative disorders. Diagnosis of solitary EMP can be made only if studies for disseminated disease and X-ray and/or magnetic resonance imaging of the spine, pelvis, femurs, and humerus and bone marrow biopsy are negative. As there are no internationally established guidelines, treatment of EMP is mainly based on consensus of expert opinion.

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Primary carcinoid tumour of nasal septum

The Journal of Laryngology & Otology ◽

10.1017/s0022215108003411 ◽

2008 ◽

Vol 123 (7) ◽

pp. 789-792 ◽

Cited By ~ 6

Author(s):

T Galm ◽

N Turner

Keyword(s):

Nasal Septum ◽

World Literature ◽

Carcinoid Syndrome ◽

Carcinoid Tumour ◽

Primary Tumour ◽

Neck Region ◽

Head And Neck Region ◽

Carcinoid Tumours ◽

History Of

AbstractObjective:We present the first reported case of primary carcinoid tumour of the nasal septum.Method:Case report of our experience of a carcinoid tumour of the nasal septum. We discuss our clinical, radiological and pathological findings.Result:An 83-year-old woman presented with a history of left-sided nasal blockage. Clinical examination showed a unilateral, left-sided nasal polyp. Further imaging and histological analysis confirmed this to be a carcinoid tumour. Carcinoid tumours outside the gastrointestinal tract are rare. There have been reports of carcinoid tumours in the head and neck region, but no published cases occurring in the nasal septum. Our management involved wide surgical resection with regular follow up to monitor for recurrence and for the development of carcinoid syndrome. Four years from initial presentation, the patient remained free of the primary tumour and had displayed no signs or symptoms suggestive of carcinoid syndrome.Conclusion:To the authors' best knowledge, and after searching the world literature, the presented case represents the first report of primary carcinoid tumour of the nasal septum. Despite its rarity, this tumour should be considered as part of the differential diagnosis, as timely recognition and intervention are critical for successful treatment.

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Tophaceous gout presenting as a dorsal nasal lump

The Journal of Laryngology & Otology ◽

10.1258/0022215054273160 ◽

2005 ◽

Vol 119 (6) ◽

pp. 492-494 ◽

Cited By ~ 11

Author(s):

J P Hughes ◽

Silvana Di Palma ◽

J Rowe-Jones

Keyword(s):

Literature Review ◽

Head And Neck ◽

Soft Tissues ◽

Neck Region ◽

Endoscopic Technique ◽

Tophaceous Gout ◽

Head And Neck Region ◽

Nasal Bones ◽

Aesthetic Rhinoplasty ◽

Emergency Tracheotomy

A literature review reveals that gout has been described as affecting many sites in the head and neck region, both in the arthritic and tophaceous form. Gout can often mimic malignancy or infection, and has been described as causing acute airway problems requiring emergency tracheotomy. Here we describe the first published case of tophaceous gout affecting the soft tissues overlying the nasal bones. The patient presented with a bony, hard, dorsal hump and requested aesthetic rhinoplasty.We also describe an endoscopic technique for removal of tophi using a powered microdebrider system with a protected burr head. Endoscopic powered microdebrider blade excision of tophi affecting the limbs has already been described, with reduced complications when compared with conventional curettage and debridement techniques. This is the first such application to the nose.

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Myeloid Sarcoma of the Head and Neck Region

Archives of Pathology & Laboratory Medicine ◽

10.5858/arpa.2012-0537-oa ◽

2013 ◽

Vol 137 (11) ◽

pp. 1560-1568 ◽

Cited By ~ 25

Author(s):

Jane Zhou ◽

Diana Bell ◽

L. Jeffrey Medeiros

Keyword(s):

Head And Neck ◽

Low Frequency ◽

Neck Region ◽

Immunohistochemical Analysis ◽

Myeloid Sarcoma ◽

Head And Neck Region ◽

Bone Marrow Disease ◽

Highly Sensitive ◽

History Of ◽

High Degree

Context.—Myeloid sarcoma of the head and neck region can pose diagnostic challenges because of the low frequency of myeloid sarcoma and the potential for tumors of almost any lineage to occur in the head and neck. Objective.—To study the clinicopathologic and immunohistochemical characteristics of myeloid sarcoma in the head and neck region and to review the differential diagnosis. Design.—We searched for cases of myeloid sarcoma involving the head and neck region for a 24-year period at our institution. The medical records and pathology slides were reviewed. Additional immunohistochemical stains were performed. Results.—We identified 17 patients, age 17 to 85 years. Most tumors involved the oral cavity. Myeloid sarcoma was the initial diagnosis in 9 patients (53%); the remaining 8 patients (47%) had a history of bone marrow disease. Immunohistochemical analysis using antibodies specific for lysozyme, CD43, and CD68 were highly sensitive for diagnosis but were not specific. By contrast, assessment for myeloperoxidase in this study was less sensitive but more specific. We also used antibodies specific for CD11c and CD33 in a subset of cases, and these reagents seem helpful as well. Conclusions.—The clinical presentation of myeloid sarcoma involving the head and neck, particularly the mouth, is often nonspecific, and a high degree of suspicion for the possibility of myeloid sarcoma is needed. Immunohistochemistry is very helpful for establishing the diagnosis.

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OSTEORADIONEKROSIS PASCA EKSTRAKSI GIGI PASIEN DENGAN RIWAYAT KANKER NASOFARING

ODONTO Dental Journal ◽

10.30659/odj.6.1.19-22 ◽

2019 ◽

Vol 6 (1) ◽

pp. 19

Author(s):

Yayun Siti Rochmah

Keyword(s):

Neck Region ◽

The Body ◽

Dental Extraction ◽

Head And Neck Region ◽

Radio Therapy ◽

Patient Reported ◽

Immunity Factor ◽

History Of ◽

Post Radiation ◽

One Year

Background: Osteoradionecrosis (ORN) post dental extraction is post dentalextraction complication with post radiation cancer theraphy. Objective : to present rare case, ORN post dental extraction with post radiation Ca nasopharing therapy 3 years ago.Case Management: A 54 years old patient reported to the dental out-patient department with a chief complaint of pus discharge from right buccal since post dental extraction 6 months ago. He gave a history of a nasopharing Carcinoma with histopatology as squamous cell carcinoms 3 years ago and radio therapy but no surgery. Intraoral examination, exposed necrotic bone found from right lower retromolar area 46 with pus discharge. Radiographic view was likely squester. Local surgical debridement and the sequestrectomy was undertaken with general anaesthesia. Antibiotic injection treatment was ceftriaxon 2x 1gram, infus metronidazol 3x500 mg and ketorolac 3x1 ampul, the patient was treated for 3 days and educated to maintain his oral hygiene with povidone iodine gargle.Discussion: Osteoradionecrosis (ORN) is late effect of radiation therapy thatresults in irreversible tissue death, which is clinically observed as bony exposure for more than 3 months duration. The mandible is affected more often than the maxilla or any other bones of head and neck region. The incidence of ORN in the mandible is reported to be between 2% and 22% and most often affects the body of the mandible. Ideal time is one year minimal post radiotherapy to get maximal vascularization for optimal healing. But immunity factor and radiation doses can trigger emergense ORN.Conclusion: Need time consideration, clinic analysis and pathologys before doing dental extraction for post radiotherapy cancer cases to prevent ORN.

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Childhood Pilomatrixoma: Case Series from a Single Center

Trends in Pediatrics ◽

10.5222/tp.2020.43534 ◽

2020 ◽

Author(s):

Begümhan Demir Gündoğan ◽

Fatih Sağcan ◽

Mehmet Alakaya ◽

Ferah Tuncel Daloğlu ◽

Elvan Çağlar Çıtak

Keyword(s):

Differential Diagnosis ◽

Medical Records ◽

Clinical Presentation ◽

Case Series ◽

Neck Region ◽

Head And Neck Region ◽

Common Causes ◽

Institutional Experience ◽

History Of ◽

Associated Conditions

INTRODUCTION: The aim of this study is to describe our institutional experience with pilomatrixoma in children, specifically examining its clinical presentation, associated conditions, radiological and pathological findings and attract attention to differential diagnosis for this tumor. METHODS: The medical records of 52 patients were reviewed retrospectively. RESULTS: There were a total of 62 tumors in 52 children. The median age at excision was 9.5 years old. Tumors were predominantly located in head and neck region (48.4%). One patient had a family history of pilomatrixoma. One patient had Turner Syndrome and one had Tuberous Sclerosis complex. Fifty-four lesions were examined by ultrasonography (USG). Pilomatrixoma was considered in the differential diagnosis in eight patients (15.3%) by a radiologist. DISCUSSION AND CONCLUSION: Pilomatrixoma is one of the most common causes of superficial masses in children. It should be kept in mind for differential diagnosis in children with superficial masses.

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Fine needle aspiration cytology of head and neck lesions and its correlation with histopathology

Journal of Pathology of Nepal ◽

10.3126/jpn.v6i12.16276 ◽

2016 ◽

Vol 6 (12) ◽

pp. 985-989

Author(s):

R Pathak ◽

KBR Prasad ◽

SK Rauniyar ◽

S Pudasaini ◽

K Pande ◽

...

Keyword(s):

Salivary Gland ◽

Lymph Node ◽

Thyroid Gland ◽

Head And Neck ◽

Soft Tissues ◽

Neck Region ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Head And Neck Region ◽

Needle Aspiration Cytology

Background: Fine needle aspiration cytology is a minimally invasive technique used in the initial diagnosis of different types of lesions located in head and neck region commonly originating from cervical lymph node, thyroid gland, salivary glands and soft tissues. The objective of this study was to evaluate the diagnostic accuracy, sensitivity and speci city of FNAC in various head and neck lesions in correlation with their histopathological examination. Materials and methods: A hospital based prospective study was conducted among 209 patients with palpable head and neck region swellings in the Department of Pathology, Bhaktapur Cancer Hospital and the Department of Pathology, Nepal Medical College from August 2014 to July 2015. FNAC were done from palpable masses of head and neck regions. Data entry and analysis were done using SPSS 17. Result: There were 209 FNAC cases enrolled, out of which lymph node lesions (n=128) were the most common lesions followed by thyroid (n=40), other soft tissues (n=27) and salivary gland (n=14). Reactive lymph nodes, colloid goiter, epidermoid cyst and sialadenosis were the predominant diagnosis of lymph nodes, thyroid gland, soft tissues and salivary gland respectively. Highest accuracy, sensitivity and speci city were observed in thyroid gland, salivary gland and soft tissues. However, four false negative results for malignancy were reported in lymph node lesions. Conclusion: Head and neck region swellings are the commonly encountered conditions. FNAC being highly accurate, sensitive and speci c makes it useful and reliable procedure for screening and diagnosis of palpable masses in head and neck region.

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Odontogenic choristoma embedded in the cheek of an old patient

BMJ Case Reports ◽

10.1136/bcr-2021-245733 ◽

2021 ◽

Vol 14 (10) ◽

pp. e245733

Author(s):

Guido Gabriele ◽

Simone Benedetti ◽

Fabiola Rossi ◽

Paolo Gennaro

Keyword(s):

Skin Lesion ◽

Histological Study ◽

Neck Region ◽

Early Age ◽

Histopathological Diagnosis ◽

Unique Case ◽

Head And Neck Region ◽

Dental Procedures ◽

History Of ◽

The Right

Odontogenic choristomas are a rare and recently classified entity, defined as neoplasms containing tissues of odontogenic derivation, found in abnormal locations and usually diagnosed in the early age. The authors report a unique case of a 79-year-old patient who presented to our attention for a skin lesion in the right cheek with no history of trauma or recent dental procedures, that underneath presented an indolent tooth-like structure inside the soft tissue of the right cheek, which at the histological study resulted to be an odontogenic choristoma. This rare histopathological diagnosis should be considered when a hard lesion is present in the head and neck region.

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TMJ pain as a presentation of metastatic breast cancer to the right mandibular condyle

BMJ Case Reports ◽

10.1136/bcr-2021-241601 ◽

2021 ◽

Vol 14 (3) ◽

pp. e241601

Author(s):

Victor Ken On Chang ◽

Samuel Thambar

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Head And Neck ◽

Cancer Metastasis ◽

Mandibular Condyle ◽

Metastatic Breast ◽

Neck Region ◽

Head And Neck Region ◽

History Of ◽

The Right

Cancer metastasis to the oral and maxillofacial region is uncommon, and metastasis to the mandibular condyle is considered rare. We present a case of a 56-year-old woman with a history of invasive ductal cell carcinoma of the right breast, 10 years in remission, presenting with a 6-month history of symptoms typical of temporomandibular joint (TMJ) dysfunction. Imaging revealed an osteolytic lesion of her right TMJ and subsequent open biopsy confirmed the diagnosis of metastatic breast cancer. Despite the rarity of metastatic cancer to the head and neck region, it is still important for clinicians from both medical and dental backgrounds to consider this differential diagnosis, particularly in patients with a history of hormonal positive subtype of breast cancer. Given that bony metastasis can manifest even 10 years after initial diagnosis, surveillance which includes examination of the head and neck region is important, and may include routine plain-film imaging surveillance with an orthopantomogram (OPG).

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Rhabdomyosarcoma of the Oral Cavity: A Case Report

European Journal of Dentistry ◽

10.1055/s-0039-1698902 ◽

2011 ◽

Vol 05 (03) ◽

pp. 340-343 ◽

Cited By ~ 10

Author(s):

Ozkan Miloglu ◽

Sare Sipal Altas ◽

Mustafa Cemil Buyukkurt ◽

Burak Erdemci ◽

Oguzhan Altun

Keyword(s):

Skeletal Muscle ◽

Case Report ◽

Soft Tissue ◽

Oral Cavity ◽

Head And Neck ◽

Soft Tissues ◽

Neck Region ◽

Childhood And Adolescence ◽

Head And Neck Region ◽

The Common

ABSTRACTRhabdomyosarcoma (RMS), a tumor of skeletal muscle origin, is the most common soft tissue sarcoma encountered in childhood and adolescence. The common sites of occurrence are the head and neck region, genitourinary tract, retroperitonium, and, to a lesser extent, the extremities. In the head and neck region, the most commonly affected sites are the orbit, paranasal sinuses, soft tissues of the cheek, and the neck. RMS is relatively uncommon in the oral cavity, and the involvement of the jaws is extremely rare. Here, we report a case of oral RMS in a 13-year-old child and describe the clinical, radiological, histopathological, and immunohistochemical findings. (Eur J Dent 2011;5:340-343)

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