scholarly journals Planetary Cities: Fluid Rock Foundations of Civilization

2021 ◽  
pp. 026327642110309
Author(s):  
Nigel Clark

Whereas recent framings of planetary urbanization stress the planet-scaled impacts of contemporary urban processes, we might also conceive of cities as being constitutively ‘planetary’ from their very outset. This article looks at two ways in which the earliest urban centres or ‘civilizations’ on the floodplains of the Fertile Crescent harnessed the deep, geological forces of the Earth. The first is the tapping and channelling of sedimentary processes, central to what Wittfogel referred to as hydraulic civilizations (1963). The second is the use of high-heat technologies to smelt and forge metals, which can be construed as a capture of igneous processes. What both sets of practices have in common is that they involve skilled intervention in fluid-solid phase transitions between solid rock and flowing particulate matter. Viewing cities as constitutively geological or planetary in this way can help us reimagine the challenges posed to urban spaces by looming transformations in Earth systems.

Biomolecules ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1014
Author(s):  
Macy L. Sprunger ◽  
Meredith E. Jackrel

Aberrant protein folding underpins many neurodegenerative diseases as well as certain myopathies and cancers. Protein misfolding can be driven by the presence of distinctive prion and prion-like regions within certain proteins. These prion and prion-like regions have also been found to drive liquid-liquid phase separation. Liquid-liquid phase separation is thought to be an important physiological process, but one that is prone to malfunction. Thus, aberrant liquid-to-solid phase transitions may drive protein aggregation and fibrillization, which could give rise to pathological inclusions. Here, we review prions and prion-like proteins, their roles in phase separation and disease, as well as potential therapeutic approaches to counter aberrant phase transitions.


1994 ◽  
Vol 127 (1) ◽  
pp. 41-99 ◽  
Author(s):  
Paolo Cermelli ◽  
Morton E. Gurtin

2018 ◽  
Author(s):  
P. Bowlan ◽  
L. Smilowitz ◽  
B. F. Henson ◽  
N. Suvorova ◽  
D. Oschwald

Sign in / Sign up

Export Citation Format

Share Document