scholarly journals The VVSymQ® instrument: Use of a new patient-reported outcome measure for assessment of varicose vein symptoms

2016 ◽  
Vol 31 (7) ◽  
pp. 481-488 ◽  
Author(s):  
Jean Paty ◽  
Diane M Turner-Bowker ◽  
Celeste A Elash ◽  
David Wright
Keyword(s):  
Varicose Vein ◽  
Varicose Veins ◽  
Daily Diary ◽  
Patient Reported Outcome ◽  
Post Intervention ◽  
Treatment Benefit ◽  
Outcome Instrument ◽  
Patient Reported ◽  
Measuring Change ◽  
Valid Instrument

Introduction No existing patient-reported outcome instrument focuses solely on assessment of varicose veins symptoms that are bothersome to patients. Methods The VVSymQ® instrument is a five-item patient-reported outcome that assesses symptoms most important to patients with varicose veins (heaviness, achiness, swelling, throbbing and itching). This paper describes how the VVSymQ® instrument was incorporated into an electronic daily diary to monitor key outcomes over time and capture treatment benefit in two randomized, controlled, phase 3 clinical trials. Results Patients were highly compliant in completing the electronic daily diary, and the VVSymQ® instrument demonstrated ability to detect overall change and ability to detect change that is meaningful to patients. Conclusion The VVSymQ® instrument is a reliable, valid instrument responsive to measuring change in the patient experience of varicose vein symptoms pre- and post-intervention, and is uniquely focused on patient-reported symptoms compared with other widely used questionnaires completed by clinicians.

scholarly journals The endometriosis daily diary: qualitative research to explore the patient experience of endometriosis and inform the development of a patient-reported outcome (PRO) for endometriosis-related pain

2022 ◽  
Vol 6 (1) ◽  
Author(s):  
Yanfen Guan ◽  
Allison M. Nguyen ◽  
Samantha Wratten ◽  
Sharan Randhawa ◽  
Jessica Weaver ◽  
...  
Keyword(s):  
Qualitative Research ◽  
Conceptual Model ◽  
Daily Diary ◽  
Patient Reported Outcome ◽  
Psychometric Validation ◽  
Handheld Device ◽  
Concept Elicitation ◽  
Chronic Disorder ◽  
Patient Reported ◽  
Valid Instrument

Abstract Purpose Endometriosis is a chronic disorder of the female reproductive system characterized by debilitating symptoms, particularly endometriosis-related pain (ERP). Patient-reported outcome (PRO) measures of symptoms and impacts are required to assess disease severity in ERP clinical studies and clinical practice. A content-valid instrument was developed by modifying the Dysmenorrhea Daily Diary (DysDD) to form the Endometriosis Daily Diary (EDD), an electronic PRO administered via handheld device. Methods Qualitative research with US females with ERP was conducted in three stages: (1) Development of an endometriosis conceptual model based on qualitative literature and conduct of concept elicitation (CE) interviews (N = 30). (2) Cognitive debriefing (CD) interviews (N = 30) conducted across two rounds to assess relevance and understanding of the EDD, with modifications between interview rounds. (3) Pilot testing to assess usability/feasibility of administrating the EDD daily on an electronic handheld device (N = 15). Clinical experts provided guidance throughout the study. Results The conceptual model provided a comprehensive summary of endometriosis to inform modifications to the DysDD, forming the EDD. CD results demonstrated that EDD items were relevant for most participants. Instructions, items, response scales, and recall period were well-understood. The resulting daily diary assesses severity of cyclic and non-cyclic pelvic pain, dyspareunia, impact of ERP on functioning and daily life, symptoms associated with ERP, and bowel symptoms. Participants were able to complete the diary daily and found the device easy to use. Conclusion The EDD demonstrated good content validity in females experiencing ERP. The next step is to perform psychometric validation in an ERP sample.

Confirmatory Psychometric Evaluation of the Axillary Sweating Daily Diary: A Vaildated Patient-Reported Outcome Measure to Assess Axillary Hyperhidrosis Sweating Severity

2017 ◽  
Vol 1 ◽  
pp. s94 ◽  
Author(s):  
Dee Anna Glaser ◽  
Adelaide A Hebert ◽  
Sheri Fehnel ◽  
Dana DiBenedetti ◽  
Lauren Nelson ◽  
...  
Keyword(s):  
Outcome Measure ◽  
Daily Diary ◽  
Psychometric Evaluation ◽  
Patient Reported Outcome ◽  
Axillary Hyperhidrosis ◽  
Patient Reported Outcome Measure ◽  
Patient Reported

Abstract Not AvailableDisclosure: Study supported by Dermira.

Psychometric validation of the dysmenorrhea daily diary (DysDD): a patient-reported outcome for dysmenorrhea

2017 ◽  
Vol 26 (8) ◽  
pp. 2041-2055 ◽  
Author(s):  
Allison M. Nguyen ◽  
Rob Arbuckle ◽  
Tjeerd Korver ◽  
Fang Chen ◽  
Beverley Taylor ◽  
...  
Keyword(s):  
Daily Diary ◽  
Patient Reported Outcome ◽  
Psychometric Validation ◽  
Patient Reported

scholarly journals Comparison of Chief Complaints and Patient-Reported Symptoms of Treatment-Naive Lung Cancer Patients Before Surgery

2021 ◽  
Author(s):  
Yaqian Feng ◽  
Wei Dai ◽  
Yaqin Wang ◽  
Jia Liao ◽  
Xing Wei ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Physical Examination ◽  
Cancer Patients ◽  
Patient Reported Outcome ◽  
Prospective Longitudinal Study ◽  
Lung Cancer Patients ◽  
Outcome Instrument ◽  
Patient Reported ◽  
Chief Complaints ◽  
Prospective Longitudinal

Abstract BackgroundLung cancer patients without chief complaints have been increasingly identified by physical examination. This study aimed to profile and compare chief complaints with patient-reported symptoms of lung cancer patients before surgery.MethodsData was extracted from a multicenter, prospective longitudinal study (CN-PRO-Lung 1) in China from November 2017 and January 2020. A comparison between chief complaints and patient-reported symptoms was analyzed using the Chi-squared test.ResultsA total of 201 (50.8%) lung cancer patients without chief complaints were found by physical examination at admission, and 195(49.2%) patients had chief complaints. The top 5 chief complaints were coughing (38.1%), expectoration (25.5%), chest pain (13.6%), hemoptysis (10.6%), and shortness of breath (5.1%). There were significantly more patients with chief complaints of coughing (38.1% vs. 15.0 %, P <0.001) and pain (20.5% vs. 6.9%, P<0.001) than those with the same symptoms rated ≥4 via MDASI-LC. There were less patients with chief complaints of fatigue (1.8% vs. 10.9%, P<0.001), nausea (0.3% vs. 2.5%, P=0.006), and vomiting (0.3% vs. 1.8%, p=0.032) than those with the same symptoms rated ≥4 via MDASI-LC. In patients without chief complaints, the five most common moderate to severe patient-reported symptoms were disturbed sleep (19.5%), distress (13.5%), dry mouth (13%), sadness (12%), and difficulty remembering (11.1%).ConclusionsSymptoms of lung cancer patients not included in the chief complaint could be identified via a patient-reported outcome instrument, suggesting the necessity of implementing the patient-reported outcome assessment before lung cancer surgery for better patient care.

scholarly journals Responder Definition of a Patient-Reported Outcome Instrument for Laryngopharyngeal Reflux Based on the US FDA Guidance

2015 ◽  
Vol 18 (4) ◽  
pp. 396-403 ◽  
Author(s):  
Han-Chung Lien ◽  
Chen-Chi Wang ◽  
Shou-Wu Lee ◽  
Jeng-Yuan Hsu ◽  
Hong-Zen Yeh ◽  
...  
Keyword(s):  
Laryngopharyngeal Reflux ◽  
Patient Reported Outcome ◽  
Fda Guidance ◽  
Outcome Instrument ◽  
Patient Reported ◽  
The Us ◽  
Us Fda ◽  
Definition Of

14 SCAR-Q: An Update on Field-testing a Patient-reported Outcome Instrument for Burn, Surgical, and Traumatic Scars

2018 ◽  
Vol 39 (suppl_1) ◽  
pp. S11-S11
Author(s):  
N I Ziolkowski ◽  
L R Mundy ◽  
A Pusic ◽  
J S Fish ◽  
A Klassen
Keyword(s):  
Field Testing ◽  
Patient Reported Outcome ◽  
Outcome Instrument ◽  
Patient Reported
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