scholarly journals Calcium silicate as a graft material for bone fractures: a systematic review

2018 ◽  
Vol 46 (7) ◽  
pp. 2537-2548 ◽  
Author(s):  
Marcelo Sanmartin de Almeida ◽  
Gustavo Vicentis de Oliveira Fernandes ◽  
Aline Muniz de Oliveira ◽  
José Mauro Granjeiro
Keyword(s):  
Systematic Review ◽  
Bone Graft ◽  
Calcium Silicate ◽  
Bone Fractures ◽  
Research Question ◽  
Evidence Base ◽  
Autogenous Bone ◽  
Graft Material ◽  
Bone Graft Material ◽  
Initial Research

Objective The goal of this review was to determine whether calcium silicate (wollastonite) as a bone graft material is a viable alternative to autogenous bone or whether the evidence base for its use is weak. Methods In this systematic review, electronic databases (MEDLINE/PubMed and BVS) were searched for relevant articles in indexed journals. Articles published in a 10-year period were identified (n = 48). After initial selection, 17 articles were assessed for eligibility; subsequently, seven articles were excluded and 10 articles were included. Results Among the studies included, 20% emphasized the importance of randomization, which adds reliability to the study, minimizing the risk of bias. High variability was observed in the material used, such as additives, amounts, dosage, and chemical alterations, rendering direct comparison among these studies impossible. The experimental periods varied considerably; one of the studies did not include statistical analysis, weakening the evaluation. Nonetheless, the true potential of wollastonite as a graft material conducive to new bone formation was reported in all studies. Conclusion The results support the use of wollastonite as a bone graft material. The initial research question was answered despite the significant variability observed among these preclinical studies, which hindered the precision of this analysis.

scholarly journals Evaluation of New Octacalcium Phosphate-Coated Xenograft in Rats Calvarial Defect Model on Bone Regeneration

Materials ◽  
2020 ◽  
Vol 13 (19) ◽  
pp. 4391
Author(s):  
Yoona Jung ◽  
Won-Hyeon Kim ◽  
Sung-Ho Lee ◽  
Kyung Won Ju ◽  
Eun-Hee Jang ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Graft ◽  
Octacalcium Phosphate ◽  
Autogenous Bone ◽  
Graft Material ◽  
Calvarial Defect ◽  
Bone Area ◽  
Defect Model ◽  
Bone Graft Material ◽  
Experimental Group

Bone graft material is essential for satisfactory and sufficient bone growth which leads to a successful implant procedure. It is classified into autogenous bone, allobone, xenobone and alloplastic materials. Among them, it has been reported that heterogeneous bone graft material has a porous microstructure that increases blood vessels and bone formation, and shows faster bone formation than other types of bone graft materials. We observed new bone tissue formation and bone remodeling using Ti-oss® (Chiyewon Co., Ltd., Guri, Korea), a heterologous bone graft material. Using a Sprague–Dawley rat calvarial defect model to evaluate the bone healing effect of biomaterials, the efficacy of the newly developed xenograft Ti-oss® and Bio-Oss® (Geistilch Pharma AG, Wolhusen, Switzerland). The experimental animals were sacrificed at 8 and 12 weeks after surgery for each group and the experimental site was extracted. The average new bone area for the Ti-oss® experimental group at 8 weeks was 17.6%. The remaining graft material was 22.7% for the experimental group. The average new bone area for the Ti-oss® group was 24.3% at 12 weeks. The remaining graft material was 22.8% for the experimental group. It can be evaluated that the new bone-forming ability of Ti-oss® with octacalcium phosphate (OCP) has the bone-forming ability corresponding to the conventional products.

scholarly journals Indirect sinus lift without bone graft material: Systematic review and meta-analysis

2015 ◽  
pp. e316-e319 ◽  
Author(s):  
S Perez-Martinez ◽  
L Martorell-Calatayud ◽  
D Penarrocha-Oltra ◽  
B Garcia-Mira ◽  
M Penarrocha-Diago
Keyword(s):  
Systematic Review ◽  
Bone Graft ◽  
Meta Analysis ◽  
Graft Material ◽  
Sinus Lift ◽  
Bone Graft Material ◽  
Without Bone Graft

Tooth Derived Bone Graft Material

2016 ◽  
Vol 7 (1) ◽  
pp. 32-35 ◽  
Author(s):  
Kalyana Chakravarthy Pentapati ◽  
Komal Smriti ◽  
Chayanika Bhattacharjya ◽  
Srikanth Gadicherla ◽  
Abhay Taranath Kamath
Keyword(s):  
Bone Graft ◽  
Bone Regeneration ◽  
Bone Grafting ◽  
Alveolar Bone ◽  
Autogenous Bone ◽  
Graft Material ◽  
Bone Graft Material ◽  
Dentin Matrix ◽  
Demineralized Dentin Matrix ◽  
Demineralized Dentin

ABSTRACT Alveolar bone deficiency is a major postoperative complication in the treatment of traumatic injuries, periodontal diseases and likewise. Hence, alveolar bone repair remains a major hurdle in tissue engineering. Autogenous bone can be wellthought- of as benchmark for bone grafting sans its limitations and complications. In order to overcome these limitations, there is an increased demand of bone graft materials that led to numerous studies on different techniques and materials for bone regeneration over the years. Dentin and bone having same biochemical similarities led to the idea of using it as a bone regenerative material. Demineralized dentin matrix (DDM), an organic material obtained from dentin has been shown to possess osteogenic capacity. Demineralized dentin matrix may prosper in future endodontic world as an apexification material and as a permanent root canal filling material as well. Quick in bone forming as compared to conventional bone graft, this material is a boon to the dental world in this era. This manuscript reviews various studies on different types of DDM as a bone grafting material, and also summarizes the suggested pathway of bone regeneration. How to cite this article Bhattacharjya C, Gadicherla S, Kamath AT, Smriti K, Pentapati KC. Tooth Derived Bone Graft Material. World J Dent 2016;7(1):32-35.

Assessment of α-calcium sulfate hemihydrate/nanocellulose composite bone graft material for bone healing in a rabbit femoral condyle model

2021 ◽  
Vol 11 (9) ◽  
pp. 1497-1504
Author(s):  
Jinlong Liu ◽  
Yicai Zhang ◽  
Lin Qiu ◽  
Yujuan Zhang ◽  
Bin Gao
Keyword(s):  
Bone Graft ◽  
Calcium Sulfate ◽  
Biological Activities ◽  
Femoral Condyle ◽  
Three Dimensional ◽  
Graft Material ◽  
Bone Graft Material ◽  
Calcium Sulfate Hemihydrate ◽  
Composite Bone

The material properties of nanocellulose (NC) can effectively enhance the structural stability of composite materials. However, the research related to NC/α-calcium sulfate hemihydrate (CSH) composites is largely lacking. In this paper, we explore the combination of these two materials and determine their elaborate biological activities in vivo. Using α-CSH as the matrix, the composite bone graft materials were produced according to different proportions of NC. Then the mechanical strength of the composite bone graft was measured, and the results were analyzed by X-ray diffraction and scanning electron microscopy (SEM). To conduct the material in vivo evaluation, 0% (CN0) and 0.75% (CN0.75) NC/α-CSH composite bone graft materials were implanted into a femoral condyle defect model. The results indicated that NC could significantly enhance the mechanical properties of α-CSH. The SEM analysis indicated that the NC shuttled between the crystal gaps and formed a three-dimensional network structure, which was firmly combined with the crystal structure. Meanwhile, the CN0.75 scaffold remained at 12 weeks postoperation, which provided a long-term framework for new bone formation. Overall, our findings demonstrate that, with a 0.75% NC/α-CSH composite demonstrating good potential as a bone graft material for clinical bone grafting.

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