scholarly journals Dynamic changes in computed tomography manifestations of 105 patients with novel coronavirus pneumonia in Wuhan, China

2020 ◽  
Vol 48 (11) ◽  
pp. 030006052097291
Author(s):  
Yueying Pan ◽  
Liming Xia ◽  
Yujin Wang ◽  
Hanxiong Guan
Keyword(s):  
Computed Tomography ◽  
Lower Lobe ◽  
Initial Symptom ◽  
Disease Course ◽  
High Resolution Computed Tomography ◽  
Quantitative Ct ◽  
Dynamic Changes ◽  
Lung Abnormalities ◽  
Initial Symptoms ◽  
Novel Coronavirus

Objective To observe the evolution of chest high-resolution computed tomography (HRCT) manifestations in 105 patients with coronavirus disease 2019 (COVID-19). Methods One hundred five patients with confirmed COVID-19 were enrolled from 11 January to 9 February 2020. Sequential chest HRCT examinations were performed. Five stages were identified from the onset of initial symptoms: 0–3, 4–7, 8–14, 15–21, and >21 days (Stages A–E, respectively). A semi-quantitative CT scoring system was used to estimate the sum of lung abnormalities in each stage. Results In total, 393 CT scans were collected. The patients underwent 3.8 ± 1.5 CT examinations. Multiple lobes were involved in most cases. The proportion of consolidation and the total CT score gradually increased from Stage A to C and gradually decreased from Stage C to E. The total CT score of lung involvement was significantly higher in Stage C than in Stages B and D. The CT score of the lower lobe was significantly higher than the corresponding upper and middle lobes in Stages A to D. Conclusions Most patients with COVID-19 had a disease course of >14 days, and the lung lesions in most patients improved after 14 days since initial symptom onset.

scholarly journals Evaluation of dynamic lung changes during coronavirus disease 2019 (COVID-19) by quantitative computed tomography

2020 ◽  
Vol 28 (5) ◽  
pp. 863-873
Author(s):  
Cong Shen ◽  
Nan Yu ◽  
Shubo Cai ◽  
Jie Zhou ◽  
Jiexin Sheng ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Quantitative Computed Tomography ◽  
Lower Lobe ◽  
Ground Glass Opacity ◽  
Middle Lobe ◽  
Lesion Volume ◽  
Dynamic Changes ◽  
Initial Symptoms ◽  
Right Middle Lobe ◽  
The Right

OBJECTIVES: This study aims to trace the dynamic lung changes of coronavirus disease 2019 (COVID-19) using computed tomography (CT) images by a quantitative method. METHODS: In this retrospective study, 28 confirmed COVID-19 cases with 145 CT scans are collected. The lesions are detected automatically and the parameters including lesion volume (LeV/mL), lesion percentage to lung volume (LeV%), mean lesion density (MLeD/HU), low attenuation area lower than – 400HU (LAA-400%), and lesion weight (LM/mL*HU) are computed for quantification. The dynamic changes of lungs are traced from the day of initial symptoms to the day of discharge. The lesion distribution among the five lobes and the dynamic changes in each lobe are also analyzed. RESULTS: LeV%, MLeD, and LM reach peaks on days 9, 6 and 8, followed by a decrease trend in the next two weeks. LAA-400% (mostly the ground glass opacity) declines to the lowest on days 4–5, and then increases. The lesion is mostly seen in the bilateral lower lobes, followed by the left upper lobe, right upper lobe and right middle lobe (p < 0.05). The right middle lobe is the earliest one (on days 6–7), while the right lower lobe is the latest one (on days 9–10) that reaches to peak among the five lobes. CONCLUSIONS: Severity of COVID-19 increases from the day of initial symptoms, reaches to the peak around on day 8, and then decreases. Lesion is more commonly seen in the bilateral lower lobes.

scholarly journals Complete Disappearance of Lung Abnormalities on High-Resolution Computed Tomography: A Case of Histiocytosis X

2007 ◽  
Vol 14 (4) ◽  
pp. 235-237 ◽  
Author(s):  
Sergio Negrin-Dastis ◽  
Dominique Butenda ◽  
Jacques Dorzee ◽  
Jacques Fastrez ◽  
Jean-Paul d’Odémont
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Lung Biopsy ◽  
Langerhans Cell Histiocytosis ◽  
Complete Disappearance ◽  
High Resolution Computed Tomography ◽  
Pulmonary Langerhans Cell Histiocytosis ◽  
Lung Abnormalities ◽  
Computed Tomography Scans

A case of pulmonary Langerhans cell histiocytosis, proved by both lung high-resolution computed tomography and lung biopsy, is described. Following smoking cessation, lung nodules and cysts gradually disappeared on serial computed tomography scans, with complete clearance of the lesions after 12 months. The role of tobacco smoking is discussed, in detail, against the background of the literature.

scholarly journals Pulmonary complications in primary hypogammaglobulinemia: a survey by high resolution CT scan

2016 ◽  
Vol 65 (2) ◽  
Author(s):  
M. Gharagozlou ◽  
F.A. Ebrahimi ◽  
A. Farhoudi ◽  
A. Aghamohammadi ◽  
M.-H. Bemanian ◽  
...  
Keyword(s):  
High Resolution ◽  
Lower Lobe ◽  
Pulmonary Complications ◽  
Wall Thickening ◽  
High Resolution Computed Tomography ◽  
Lung Abnormalities ◽  
Predicted Values ◽  
The Right ◽  
Delay Of Diagnosis ◽  
Increased Susceptibility

Background. Primary hypogammaglobulinemia disorders are a group of heterogeneous immunodeficiency syndromes with an increased susceptibility to pulmonary complications. Methods. The aim of this study was to evaluate the extent of lung abnormalities in primary hypogammaglobulinaemic patients by high resolution computed tomography (HRCT) scan and pulmonary function test (PFT). HRCT and PFT were performed in 22 Iranian patients with primary hypogammaglobulinemia. Results. Pathological bronchial findings were observed in thirteen patients: three patients showed only peribronchial thickening and the remaining ten patients suffered from both bronchiectasis and peribronchial wall thickening. Mild type of bronchiectasis and peribronchial wall thickening were the most common type, predominantly observed in the right middle and both right and left lower lobe segments of lungs. Although bullae were not found, emphysema, air-trapping, and collapse/consolidation were observed in two patients. Bronchial involvement was mostly limited to 1 up to 5 bronchopulmonary segments; only one HRCT indicated bronchial involvement in more than nine bronchopulmonary segments. Pathological bronchial findings mostly observed in the proximal bronchi; meanwhile the involvement of the distal bronchi was less common. Decreasing FEV1 and FVC were observed in 65% and 55% of patients, respectively. There was a significant correlation between the HRCT score and the predicted values by PFT. The delay of diagnosis in patients with bronchiectasis was significantly higher than those without bronchiectasis. Conclusions. It seems that the majority of hypogammaglobulinaemic patients suffer from the mild type of bronchiectasis, which is mostly observed in the proximal bronchi of the lower lobe segments. The delay of diagnosis plays an important role in the occurrence of this complication in these patients.

Comparison of High Resolution Computed Tomography Features in Covid-19 and Other Viral Pneumonia-

2021 ◽  
Vol 15 (6) ◽  
pp. 1139-1144
Author(s):  
S. Nisar ◽  
F. Farooq ◽  
Rabia . ◽  
M. N. Anjum ◽  
M. Fatima ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Lower Lobe ◽  
Ground Glass Opacity ◽  
Viral Disease ◽  
Viral Pneumonia ◽  
High Resolution Computed Tomography ◽  
Keywords Computed Tomography ◽  
Comparison Results ◽  
High Prevalence

Aim: To compare the high resolution computed tomography features in Covid and other viral pneumonia presented in recent literature. Methodology: For this study, total 25 studies were included which follow the Preferred Reporting Items guideline for conducting this systematic review analysis (PRISMA). Electronic articles of Covid from January 2020 to April 2020 were searched on PUB Med, online Willey library, and Science Direct site by using keywords related to CT imaging and Corona virus. For pneumonia related studies articles from year 2010 to year 2017 were included for better comparison. Results: After pooling data, it was observed that bilateral involvement was found in 76.8% of studies, 68.4% GGO, and 62.2% ratio was occupied by peripheral distribution in different studies. Total 48.7% of studies were concerned about the ground glass opacity (GGO) consolidation, 33.2% observed consolidation, 27.7% look for crazy paving pattern, and 25% of studies observed mixed central and peripheral distribution. Conclusion: Study concludes that the chest CT finding results of selected studies for Covid and pneumonia cases were overlapping. Only high prevalence related to upper and lower lobe involvement and peripheral distribution was relatively high in Covid studies. Keywords: Computed tomography, pneumonia viral disease, Sars Covid-19

scholarly journals High resolution computed tomography for the diagnosis of 2019 novel coronavirus (2019-nCoV) pneumonia: a study from multiple medical centers in western China

2020 ◽  
Author(s):  
Hong-Wei Li ◽  
Li-Hua Zhuo ◽  
Gao-Wu Yan ◽  
Ji-Sheng Wang ◽  
Guo-Ping Huang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Early Detection ◽  
Western China ◽  
Imaging Features ◽  
High Resolution Computed Tomography ◽  
Medical Centers ◽  
Detection And Diagnosis ◽  
Novel Coronavirus ◽  
Early Detection And Diagnosis

Abstract Objective: To evaluate the role of high-resolution computed tomography (HRCT) in the diagnosis of 2019 novel coronavirus (2019-nCoV) pneumonia and to provide experience in the early detection and diagnosis of 2019-nCoV pneumonia. Methods: 72 patients confirmed to be infected with 2019-nCoV from multiple medical centers in western China were retrospectively analyzed, including epidemiologic characteristics, clinical manifestations, laboratory findings and HRCT chest features. Results: All patients had lung parenchymal abnormalities on HRCT scans, which were mostly multifocal in both lungs and asymmetric in all patients, and were mostly in the peripheral or subpleural lung regions in 52 patients (72.22%), in the central lung regions in sixteen (22.22%), and in both lungs, with "white lung "manifestations in four (5.56%). Subpleural multifocal consolidation was predominant abnormality in 38 patients (52.78%). Ground-glass opacity was seen in 34 patients (47.22%). Interlobular septal thickening was found in 18patients, of which eight had only generally mild thickening with no zonal predominance. Reticulation was seen in 8 patients (11.11%), in all of whom it was mild and randomly distributed. In addition, both lungs of 28 patients had two or three CT imaging features. Out of these 72 patients, 36 were diagnosed as early stage, 32 patients as progressive stage and 4 patient as severe stage pneumonia. Moreover, the diagnostic accuracy of HRCT features combined with epidemiological history was not significantly different from the detection of viral nucleic acid (all P >0.05). Conclusion: The HRCT features of 2019-nCoV pneumonia are characteristic to a certain degree, which when combined with epidemiological history yield high clinical value in the early detection and diagnosis of 2019-nCoV pneumonia.Authors Hong-Wei Li, Li-Hua Zhuo, Gao-Wu Yan contributed equally to this work.

scholarly journals The multicenter study of Chest HRCT imaging characteristics of 2019 Novel Coronavirus (COVID-19) Pneumonia

2020 ◽  
Author(s):  
Zhehao Lyu ◽  
Meiji Ren ◽  
Lian-Ming Wu ◽  
Yuxin Yang ◽  
Yi-Bo Lu ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Acute Respiratory Distress Syndrome ◽  
Distress Syndrome ◽  
Chest Ct ◽  
Imaging Features ◽  
Wholesale Market ◽  
High Resolution Computed Tomography ◽  
Imaging Characteristics ◽  
History Of ◽  
Novel Coronavirus

Abstract Background: In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A novel coronavirus was detected, capable of infecting humans, on 6 January 2020 and termed COVID-19. By 16 February 2020, there were 51857 confirmed cases with 2019-nCoV (COVID-19) pneumonia in 25 countries. COVID-19 can also lead to acute respiratory distress syndrome (ARDS).Methods: 149 patients with 2019 Novel Coronavirus (COVID-19)pneumonia(68 males, 81 females, ages 1-89)from 6 research centers in China were diagnosed with positive 2019 Novel Coronavirus(COVID-19)nucleic acids antibodies. And their high-resolution computed tomography(HRCT) imaging datas were evaluated.Results: 136/149(91.3%)patients had a clear history of exposure to Wuhan. Fever (122/149, 81.9%)and cough(83/149, 55.7%)were the most common symptoms. The main imaging characteristics within 4 days of onset included 30(20.13%) cases of pure ground glass opacities (P<0.05), 38(25.50%) cases of GGO with reticulation(P<0.01), 12(8.05%) cases of consolidation(P<0.01). In the 5-8 days group, the main imaging features included 71(47.65%) cases of pGGO(P<0.05), 69(46.31%) cases of GGO with reticulation(P<0.01). In the 9-12 days group, the main feature was 85(57.04%) cases with GGO with reticulation(P<0.01). In the group of 13-16 days group, the main imaging characteristics included 48(32.21%) cases of GGO with reticulation(P < 0.01), 34(22.82%) cases of consolidation(P<0.01).Conclusion: Patients infected with COVID-19 pneumonia show more chest CT characteristics within 5-8 days after the onset of disease. The main manifestations included pGGO, GGO with reticulation, consolidation and GGO with consolidation.

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