Two cases of benign abducens nerve palsy in children and their long-term follow-up

Our aim was to explore the clinical characteristics and diagnostic methods of benign abducens nerve palsy in children. The clinical and laboratory characteristics, treatment approach, and prognosis of two children with benign abducens nerve palsy were retrospectively evaluated. The main clinical symptoms of the two children were limited binocular movement accompanied by double vision, and the positive physical signs were limited binocular abduction accompanied by diplopia. No abnormalities were found in laboratory examinations or in imaging of the head, chest, and abdomen. Both children were treated with B vitamins, methylprednisolone, and gamma globulin, and the clinical symptoms disappeared within 3 months of starting treatment. The cause of benign abducens nerve palsy in children is unknown, but may be related to immune factors. In the two cases presented here, the patients recovered after treatment with immunomodulators.

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Long-term follow-up of children with benign abducens nerve palsy

Eye ◽

10.1038/eye.2009.22 ◽

2009 ◽

Vol 24 (1) ◽

pp. 74-78 ◽

Cited By ~ 7

Author(s):

V Sturm ◽

C Schöffler

Keyword(s):

Nerve Palsy ◽

Abducens Nerve ◽

Abducens Nerve Palsy ◽

Long Term Follow Up

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Intracranial Complication of Rhinosinusitis from Actinomycosis of the Paranasal Sinuses: A Rare Case of Abducens Nerve Palsy

Case Reports in Otolaryngology ◽

10.1155/2014/601671 ◽

2014 ◽

Vol 2014 ◽

pp. 1-5 ◽

Cited By ~ 2

Author(s):

G. L. Fadda ◽

M. Gisolo ◽

E. Crosetti ◽

A. Fulcheri ◽

G. Succo

Keyword(s):

Nerve Palsy ◽

Unusual Case ◽

Clinical Symptoms ◽

Abducens Nerve ◽

Abducens Nerve Palsy ◽

Sinus Surgery ◽

Facial Trauma ◽

History Of ◽

Extent Of Disease

Sinonasal actinomycosis should be suspected when a patient with chronic sinusitis does not respond to medical therapy or has a history of facial trauma, dental disease, cancer, immunodeficiency, long-term steroid therapy, diabetes, or malnutrition. Radiological evaluation with computed tomography and magnetic resonance imaging are important in differential diagnosis, evaluating the extent of disease, and understanding clinical symptoms. Endoscopic sinus surgery associated with long-term intravenous antibiotic therapy is the gold standard for treatment of sinonasal actinomycosis. We report an unusual case of abducens nerve palsy resulting from invasive sinonasal actinomycosis in a patient with an abnormally enlarged sphenoid sinus. A review of the current literature highlighting clinical presentation, radiological findings, and treatment of this uncommon complication is also presented.

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Vestibular migraine: Long-term follow-up of clinical symptoms and vestibulo-cochlear findings

Neurology ◽

10.1212/wnl.0b013e31826e264f ◽

2012 ◽

Vol 79 (15) ◽

pp. 1607-1614 ◽

Cited By ~ 89

Author(s):

A. Radtke ◽

M. von Brevern ◽

H. Neuhauser ◽

T. Hottenrott ◽

T. Lempert

Keyword(s):

Clinical Symptoms ◽

Vestibular Migraine ◽

Long Term Follow Up

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Is Longstanding Congenital Muscular Torticollis Provoking Pelvic Malalignment Syndrome?

Children ◽

10.3390/children8090735 ◽

2021 ◽

Vol 8 (9) ◽

pp. 735

Author(s):

Jun-il Park ◽

Joo-Hyun Kee ◽

Ja Young Choi ◽

Shin-seung Yang

Keyword(s):

Clinical Symptoms ◽

Limited Range ◽

Neck Mass ◽

Congenital Muscular Torticollis ◽

Limited Range Of Motion ◽

Chi Squared ◽

Long Term Follow Up ◽

Muscular Torticollis

It has been reported that congenital muscular torticollis (CMT) may result in secondary scoliosis over long-term follow-ups. However, there are few reports on whether CMT causes pelvic malalignment syndrome (PMS). This study aimed to investigate the relationship between CMT and PMS and to determine the factors associated with the development of PMS in children with longstanding CMT. Medical records of 130 children with CMT who had long-term follow-up were reviewed retrospectively. The chi-squared test and logistic regression analysis were used to determine which initial clinical parameters contributed to the development of PMS. Among 130 children with CMT, 51 (39.2%) developed PMS with or without compensatory scoliosis during long-term follow-up, indicating a high prevalence of PMS in children with a CMT history. Initial clinical symptoms such as a limited range of motion of the neck or the presence of a neck mass could not predict the development of PMS. Even if the clinical symptoms are mild, long-term follow-up of children with CMT is essential to screen for PMS.

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Abducens nerve palsy on a patient with sphenoid fungal rhinosinusitis and cavernous sinus meningioma – Case report

Romanian Journal of Rhinology ◽

10.2478/rjr-2018-0022 ◽

2018 ◽

Vol 8 (31) ◽

pp. 193-196

Author(s):

Andreea Marza ◽

Claudiu Manea

Keyword(s):

Cavernous Sinus ◽

Nerve Palsy ◽

Abducens Nerve ◽

Complete Removal ◽

Abducens Nerve Palsy ◽

Cavernous Sinus Meningioma ◽

Fungal Rhinosinusitis ◽

Wait And See ◽

The Brain

Abstract We report a case of a 47-year-old patient recently diagnosed with left abducens nerve palsy, who was admitted in our clinic with diplopia. The cranio-facial CT scan revealed left sphenoid fungal rhinosinusitis and the patient underwent endoscopic surgery with complete removal of the fungal material. The immediate postoperative evolution of the patient was favourable, with partial improvement of diplopia. The first month follow-up visit revealed the recurrence of the diplopia, so the patient performed an MRI scan of the brain that showed a cavernous sinus meningioma. The patient was referred to a neurosurgeon who choose a “wait-and-see” strategy instead of surgery. The paper presents the limits of computed tomography versus magnetic resonance imaging in the radiologic diagnosis of intracranial tumors.

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Long-term Outcomes of Patients with Anti–Leucine-Rich Glioma-Inactivated 1 Encephalitis

10.21203/rs.3.rs-76702/v1 ◽

2020 ◽

Author(s):

Shan Qiao ◽

Huai-kuan Wu ◽

Ling-ling Liu ◽

Ke-jun Zang ◽

Xuewu liu

Keyword(s):

Clinical Symptoms ◽

Early Recognition ◽

Chinese Patients ◽

Long Term Outcomes ◽

Ancillary Test ◽

Behavioral Abnormalities ◽

Long Term Follow Up ◽

And Behavior

Abstract Background: This report aims to provide a detailed description of the clinical manifestation, immunotherapy, and long-term outcomes of 117 Chinese patients with anti-leucine-rich glioma-inactivated 1 (LGI1) encephalitis. Methods: We retrospectively selected 117 patients diagnosed with anti-LGI1 encephalitis from the databases of multiple clinical centers from September 2014 to December 2019. The clinical features, ancillary test results, and details of long-term outcomes were analyzed.Results: Among the 117 anti-LGI1 encephalitis patients, 81 (69%) were male and 36 (31%) were female; the median onset age was 51 years (range: 30-77 years). The median time from symptom onset until diagnosis was 8.7 weeks (range: 2-49 weeks). The main features evaluated in our cohort were seizures, cognitive impairment, and mental and behavioral abnormalities. One hundred and nine patients were treated with immunotherapy, After 3-5 days of treatment, the clinical symptoms were somewhat alleviated in all the patients, and their memory, mental ability, and behavior improved. The median follow-up time was 33 months (range: 6-59 months). A total of 19 (16%) patients experienced a relapse; the median duration from onset to the first relapse was 5 (0.3-27) months. There were no mortalities during the follow-up period.Conclusions: The outcome of patients with anti-LGI1 encephalitis is mostly favorable, although some patients continue to suffer from cognitive dysfunction. Early recognition is of great significance for the treatment of anti-LGI1 encephalitis. Prompt adequate immunotherapy has positive implications for the improvement of clinical symptoms of anti-LGI1 encephalitis. Long-term follow-up is important for the assessment of LGI1 antibody-mediated encephalitis.

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Low Morbidity after Extracranial-Intracranial Bypass Operation. The Danish Extracranial-Intracranial Bypass Study: A Nationwide Survey

Cerebrovascular Diseases ◽

10.1159/000489895 ◽

2018 ◽

Vol 45 (5-6) ◽

pp. 252-257 ◽

Cited By ~ 1

Author(s):

Paul von Weitzel-Mudersbach ◽

Grethe Andersen ◽

Sverre Rosenbaum

Keyword(s):

Clinical Symptoms ◽

Recurrent Stroke ◽

Stroke Rate ◽

Bypass Operation ◽

Perioperative Stroke ◽

Bypass Patency ◽

Long Term Follow Up ◽

The Mean

Background: Patients with symptomatic atherosclerotic carotid artery occlusion (SACAO) have a high risk of a recurrent stroke. Extracranial-intracranial bypass (EC-IC bypass) has been shown not to improve outcome compared with medical treatment alone because long-term prevention of recurrent stroke in operated patients was offset by high perioperative stroke rates. We report our experience with EC-IC bypass operated at an experienced high-volume centre. Methods: We conducted a nationwide observational study of EC-IC bypass patients operated in the years 2007–2016 due to SACAO with ongoing clinical symptoms or progression on MRI and severe haemodynamic failure (SHF). Perioperative stroke and death within 30 days after the operation, ipsilateral stroke, bypass patency, transient ischaemic attack, and all-stroke events and deaths during long-term follow-up were registered prospectively. Results: EC-IC bypass was performed in 48 patients with SHF and SACAO. The mean age was 64 (45–83) years. The mean follow-up was 3.6 years. The stroke rate after 30 days was 4.2%. No further ipsilateral strokes occurred during follow-up. Clinical symptoms arrested in all patients. Bypass patency rate was 94%. Conclusions: The perioperative stroke rate in EC-IC bypass operation, performed at a highly experienced centre, was low. During long-term follow-up, no ipsilateral stroke occurred. Consequently, EC-IC-bypass should still be considered for selected patients with SACAO, if operation can be carried out in experienced centres with low perioperative morbidity.

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