scholarly journals Risk factors for rebleeding in patients with obscure gastrointestinal bleeding from southern China

2021 ◽  
Vol 49 (10) ◽  
pp. 030006052110284
Author(s):  
Boying Liu ◽  
Sudong Liu ◽  
Pingwu Wen ◽  
Shengbing Wang ◽  
Fuqun Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Gastrointestinal Bleeding ◽  
Southern China ◽  
Obscure Gastrointestinal Bleeding ◽  
Logistic Analysis ◽  
Increased Risk ◽  
Nitrogen Concentrations ◽  
Small Bowel Endoscopy ◽  
Multivariate Logistic Analysis

Background To identify the risk factors associated with rebleeding in obscure gastrointestinal bleeding (OGIB) patients from southern China. Methods This retrospective study involved 229 patients who underwent small bowel endoscopy in our hospital between 1 January 2018 and 1 December 2020. The clinical characteristics and risk factors related to rebleeding were retrospectively evaluated. Results Rebleeding patients were significantly older than non-rebleeding patients (53.0 ± 15.9 vs. 46.2 ± 17.8 years), had lower hemoglobin concentrations (89.2 ± 28.1 vs. 126.2 ± 25.1 g/L), and higher blood urea nitrogen concentrations (5.4 ± 2.6 vs. 4.5 ± 2.2 µmol/L), respectively. A higher percentage of rebleeding patients had diabetes mellitus (13.9% vs. 2.9%) and overt bleeding (70.4% vs. 38.6%), and required blood transfusions (43.1% vs. 8.0%), compared with non-rebleeding patients, respectively. Multivariate logistic analysis indicated that drinking alcohol (odds ratio (OR): 9.27; 95% confidence interval (CI) = 1.35–63.78), anemia (OR: 17.38; 95% CI = 5.48–55.10), and blood transfusion (OR: 3.76; 95% CI = 1.04–13.56) increased the risk of rebleeding in OGIB patients. Conclusion Our data suggested that OGIB patients who drink alcohol, have anemia, and require blood transfusion have an increased risk of rebleeding.

Development and Validation of a Nomogram for Renal Involvement in Primary Sjögren Syndrome Patients: A Retrospective Analysis

2021 ◽  
Author(s):  
Xinshi Huang ◽  
Xiaobing Wang ◽  
Dinglai Yu
Keyword(s):  
Risk Factors ◽  
Prediction Model ◽  
Receiver Operating Characteristic ◽  
Operating Characteristic ◽  
Renal Involvement ◽  
Calibration Plot ◽  
Receiver Operating Characteristic Curves ◽  
Logistic Analysis ◽  
Validation Set ◽  
Multivariate Logistic Analysis

Abstract Objective To establish and validate a nomogram for individualized prediction of renal involvement in pSS patients. Methods A total of 1293 patients with pSS from the First Affiliated Hospital of Wenzhou Medical University between January 2008 to January 2020 were recruited and further analyzed retrospectively. The patients were randomly divided into a development set (70%, n = 910) and a validation set (30%, n = 383). The univariable and multivariate logistic regression were performed to analyze the risk factors of renal involvement in pSS. Based on the regression β coefficients derived from multivariate logistic analysis, an individualized nomogram prediction model was developed. The prediction model of discrimination and calibration was evaluated with the area under the receiver operating characteristic curves and Calibration plot. Results Multivariate logistic analysis showed that hypertension, anemia, albumin, uric acid, anti-Ro52, hematuria and Chisholm-Mason grade were independent risk factors of renal involvement in pSS. The area under the receiver operating characteristic curves were 0.797 and 0.750 respectively in development set and validation set, indicating the nomogram had a good discrimination capacity. The Calibration plot showed nomogram had a strong concordance performance between the prediction probability and the actual probability. Conclusion The individualized nomogram for pSS patients those who had renal involvement could be used by clinicians to predict the risk of pSS patients developing into renal involvement and improve early screening and intervention.

Sa1644 Differences in Clinical Features and the Related Risk Factors Between Occult and Overt Cases of Obscure Gastrointestinal Bleeding

2013 ◽  
Vol 77 (5) ◽  
pp. AB278
Author(s):  
Junichi Okamoto ◽  
Satoshi Sugimori ◽  
Kazunari Tominaga ◽  
Tomoko Obayashi ◽  
Kunihiro Kato ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastrointestinal Bleeding ◽  
Clinical Features ◽  
Obscure Gastrointestinal Bleeding ◽  
Related Risk

scholarly journals Albumin infusion reduces the risk of rebleeding and in-hospital mortality in cirrhotic patients admitted for acute gastrointestinal bleeding: retrospective analysis of a single institute

2020 ◽  
Author(s):  
Zhu Wang ◽  
Ya-Wen Xie ◽  
Qing Lu ◽  
Hai-Lin Yan ◽  
Xin-Bin Liu ◽  
...  
Keyword(s):  
Blood Cell ◽  
Gastrointestinal Bleeding ◽  
Hospital Mortality ◽  
Red Blood Cell ◽  
Acute Gastrointestinal Bleeding ◽  
Albumin Infusion ◽  
Logistic Analysis ◽  
Cirrhotic Patients ◽  
Reduce Risk ◽  
Multivariate Logistic Analysis

Abstract BackgroundTo investigate the effect of albumin infusion in cirrhotic patients admitted for acute gastrointestinal bleeding.MethodsMedical records of cirrhotic patients who admitted due to acute gastrointestinal bleeding through January 2009 to December 2018 were systemically reviewed. Clinical data and the total amount of albumin and red blood cell used during hospitalization were recorded. For patients with rebleeding, the amount of albumin and red blood cell used before rebleeding was also documented. The primary outcome was the occurrence of rebleeding and the second outcome was in-hospital mortality. Univariate and multivariate logistic analysis were performed to identify risk factors associated with rebleeding and in-hospital mortality.ResultsA total of 2239 cirrhotic patients were included in the analysis. There were 245 episodes of in-patient rebleeding occurred, while 135 patients died. Overall, more red blood cells and albumin were prescribed to patients who suffered rebleeding. In terms of the amount before rebleeding, the red blood cell was higher in patients with rebleeding, but the albumin infusion were similar. In the multivariate model, the albumin infusion was an independent risk factor associated with rebleeding (adjusted OR for ≤40g, 0.385 [0.252-0.588], p<0.001; OR for >40g, 0.295 [0.169-0.514], p<0.001). The use of albumin more than 40g during hospitalization reduces the risk of in-patient mortality (adjusted OR for ≤40g, 0.730 [0.375-1.423], p=0.356; OR for >40g, 0.389 [0.180-0.838], p=0.016).ConclusionsAlbumin infusion could reduce risk of in-hospital rebleeding. Moreover, more than 40g albumin infusion decrease numbers of mortality in cirrhosis admitted for acute gastrointestinal bleeding.

scholarly journals Risk Factors for Progression to Patients with Severe Stage of COVID-19

2020 ◽  
Author(s):  
Min Cheol Chang ◽  
Yoo-Kyung Park ◽  
Bong-Ok Kim ◽  
Donghwi Park
Keyword(s):  
Risk Factors ◽  
Body Temperature ◽  
Severe Disease ◽  
Initial Symptom ◽  
X Ray ◽  
Disease States ◽  
Logistic Analysis ◽  
Severe Stage ◽  
Chest X Ray ◽  
Multivariate Logistic Analysis

Abstract Background: Coronavirus disease (COVID-19) is rapidly spreading worldwide. Although 10%–20% of patients with COVID-19 have severe symptoms, little is known about the risk factors related to the aggravation of COVID-19 symptoms from asymptomatic or mild to severe disease states. Methods: This retrospective study included 211 patients who were asymptomatic or with mild presentations of COVID-19. We evaluated the differences in in demographic and clinical data between the cured (discharged to home) and transferred (aggravated to severe-stage COVID-19) groups. Results: A multivariate logistic analysis showed that body temperature, chills, initial chest X-ray findings, and the presence of diabetes were significantly associated with predicting the progression to severe stage of COVID-19 (p < 0.05). The odds ratio of transfer in patients with COVID-19 increased by 12.7-fold for abnormal findings such as haziness or consolidation in initial chest X-ray, 6.32-fold for initial symptom of chills, and 64.1-fold for diabetes.Conclusions: Even if patients are asymptomatic or have mild symptoms, clinicians should closely observe patients with COVID-19 presenting with chills, body temperature >37.5°C, findings of pneumonia in chest X-ray, or diabetes.

Su1365 RISK FACTORS FOR RE-BLEEDING EVENTS IN OBSCURE GASTROINTESTINAL BLEEDING(OGIB)

2019 ◽  
Vol 89 (6) ◽  
pp. AB347
Author(s):  
Kanae Tao ◽  
Toshio Kuwai ◽  
Hirona Konishi ◽  
Ryoichi Miura ◽  
Yuki Sumida ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastrointestinal Bleeding ◽  
Obscure Gastrointestinal Bleeding ◽  
Bleeding Events

scholarly journals Clinical Characteristics and Risk Factors for Rebleeding in Patients with Obscure Gastrointestinal Bleeding

2020 ◽  
Vol 59 (11) ◽  
pp. 1345-1350
Author(s):  
Yuki Baba ◽  
Seiji Kawano ◽  
Yoshiyasu Kono ◽  
Toshihiro Inokuchi ◽  
Hiromitsu Kanzaki ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastrointestinal Bleeding ◽  
Clinical Characteristics ◽  
Obscure Gastrointestinal Bleeding

MULTIVARIATE LOGISTIC ANALYSIS OF RISK FACTORS FOR STROKE IN TILBURG, THE NETHERLANDS

1983 ◽  
Vol 118 (4) ◽  
pp. 514-525 ◽  
Author(s):  
BERTRAM HERMAN ◽  
PAUL I M. SCHMTTZ ◽  
ANTON C. M. LEYTEN ◽  
JACOB H. VAN LUIJK ◽  
CORNELUS W. G. M. FRENKEN ◽  
...  
Keyword(s):  
Risk Factors ◽  
The Netherlands ◽  
Logistic Analysis ◽  
Multivariate Logistic Analysis

scholarly journals Risk Factors Associated with Increased Morbidity in Living Liver Donation

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Helry L. Candido ◽  
Eduardo A. da Fonseca ◽  
Flávia H. Feier ◽  
Renata Pugliese ◽  
Marcel A. Benavides ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Smoking Status ◽  
Left Lobe ◽  
Cancer Center ◽  
Increased Risk ◽  
Left Lateral Segment ◽  
Right Lobe ◽  
Liver Donation ◽  
Living Liver Donation

Living donor liver donation (LDLD) is an alternative to cadaveric liver donation. We aimed at identifying risk factors and developing a score for prediction of postoperative complications (POCs) after LDLD in donors. This is a retrospective cohort study in 688 donors between June 1995 and February 2014 at Hospital Sírio-Libanês and A.C. Camargo Cancer Center, in São Paulo, Brazil. Primary outcome was POC graded ≥III according to the Clavien-Dindo classification. Left lateral segment (LLS), left lobe (LL), and right lobe resections (RL) were conducted in 492 (71.4%), 109 (15.8%), and 87 (12.6%) donors, respectively. In total, 43 (6.2%) developed POCs, which were more common after RL than LLS and LL (14/87 (16.1%) versus 23/492 (4.5%) and 6/109 (5.5%), resp.,p<0.001). Multivariate analysis showed that RL resection (OR: 2.81, 95% CI: 1.32 to 3.01;p=0.008), smoking status (OR: 3.2, 95% CI: 1.35 to 7.56;p=0.012), and blood transfusion (OR: 3.15, 95% CI: 1.45 to 6.84;p=0.004) were independently associated with POCs. RL resection, intraoperative blood transfusion, and smoking were associated with increased risk for POCs in donors.

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