Sa1644 Differences in Clinical Features and the Related Risk Factors Between Occult and Overt Cases of Obscure Gastrointestinal Bleeding

Abstract Background Coronavirus disease 2019 (COVID-19) has spread around the world. This retrospective study aims to analyze the clinical features of COVID-19 patients with cancer and identify death outcome related risk factors. Methods From February 10th to April 15th, 2020, 103 COVID-19 patients with cancer were enrolled. Difference analyses were performed between severe and non-severe patients. A propensity score matching (PSM) analysis was performed, including 103 COVID-19 patients with cancer and 206 matched non-cancer COVID-19 patients. Next, we identified death related risk factors and developed a nomogram for predicting the probability. Results In 103 COVID-19 patients with cancer, the main cancer categories were breast cancer, lung cancer and bladder cancer. Compared to non-severe patients, severe patients had a higher median age, and a higher proportion of smokers, diabetes, heart disease and dyspnea. In addition, most of the laboratory results between two groups were significantly different. PSM analysis found that the proportion of dyspnea was much higher in COVID-19 patients with cancer. The severity incidence in two groups were similar, while a much higher mortality was found in COVID-19 patients with cancer compared to that in COVID-19 patients without cancer (11.7% vs. 4.4%, P = 0.028). Furthermore, we found that neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein (CRP) were related to death outcome. And a nomogram based on the factors was developed. Conclusion In COVID-19 patients with cancer, the clinical features and laboratory results between severe group and non-severe group were significantly different. NLR and CRP were the risk factors that could predict death outcome.

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Clinical Features of Stroke

10.4018/978-1-7998-7433-1.ch008 ◽

2022 ◽

pp. 120-137

Author(s):

Alper Uysal

Keyword(s):

Risk Factors ◽

Clinical Features ◽

Language Disorders ◽

Signs And Symptoms ◽

Neurological Dysfunction ◽

Related Risk ◽

Prolongation Of Life ◽

Ischemic Attack ◽

Speech And Language Disorders ◽

The Brain

Stroke is a clinical condition that causes neurological dysfunction due to focal infarction or haemorrhage in the brain, spinal cord, or retina. These clinical features may take 24 hours or more and result in death. Stroke is one of the leading causes of disability and death. With the prolongation of life in societies, stroke and stroke-related risk factors become more and more important. Age, gender, race, heredity, ethnicity, hypertension, atrial fibrillation, diabetes, hyperlipidemia, smoking, transient ischemic attack, and physical inactivity are risk factors of stroke. Signs and symptoms of stroke vary according to occluded vessel. Mental dysfunction, speech and language disorders, motor and sensory impairment may occur as a result of stroke.

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Clinical Features of Renal Insufficiency due to Multiple Myeloma and Related Risk Factors

The Chinese-German Journal of Clinical Oncology ◽

10.1007/s10330-003-0169-9 ◽

2005 ◽

Vol 4 (1) ◽

pp. 47-49 ◽

Cited By ~ 1

Author(s):

Xuemei LIU ◽

Jinlan XU ◽

Xuhua GUAN ◽

Liqiu LIU

Keyword(s):

Risk Factors ◽

Multiple Myeloma ◽

Renal Insufficiency ◽

Clinical Features ◽

Related Risk

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Risk factors for rebleeding in patients with obscure gastrointestinal bleeding from southern China

Journal of International Medical Research ◽

10.1177/03000605211028422 ◽

2021 ◽

Vol 49 (10) ◽

pp. 030006052110284

Author(s):

Boying Liu ◽

Sudong Liu ◽

Pingwu Wen ◽

Shengbing Wang ◽

Fuqun Wang ◽

...

Keyword(s):

Risk Factors ◽

Blood Transfusion ◽

Gastrointestinal Bleeding ◽

Southern China ◽

Obscure Gastrointestinal Bleeding ◽

Logistic Analysis ◽

Increased Risk ◽

Nitrogen Concentrations ◽

Small Bowel Endoscopy ◽

Multivariate Logistic Analysis

Background To identify the risk factors associated with rebleeding in obscure gastrointestinal bleeding (OGIB) patients from southern China. Methods This retrospective study involved 229 patients who underwent small bowel endoscopy in our hospital between 1 January 2018 and 1 December 2020. The clinical characteristics and risk factors related to rebleeding were retrospectively evaluated. Results Rebleeding patients were significantly older than non-rebleeding patients (53.0 ± 15.9 vs. 46.2 ± 17.8 years), had lower hemoglobin concentrations (89.2 ± 28.1 vs. 126.2 ± 25.1 g/L), and higher blood urea nitrogen concentrations (5.4 ± 2.6 vs. 4.5 ± 2.2 µmol/L), respectively. A higher percentage of rebleeding patients had diabetes mellitus (13.9% vs. 2.9%) and overt bleeding (70.4% vs. 38.6%), and required blood transfusions (43.1% vs. 8.0%), compared with non-rebleeding patients, respectively. Multivariate logistic analysis indicated that drinking alcohol (odds ratio (OR): 9.27; 95% confidence interval (CI) = 1.35–63.78), anemia (OR: 17.38; 95% CI = 5.48–55.10), and blood transfusion (OR: 3.76; 95% CI = 1.04–13.56) increased the risk of rebleeding in OGIB patients. Conclusion Our data suggested that OGIB patients who drink alcohol, have anemia, and require blood transfusion have an increased risk of rebleeding.

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