Mobile Telecare System for Intensive Insulin Treatment and Patient Education. First Applications for Newly Diagnosed Type 1 Diabetic Patients

2006 ◽  
Vol 29 (11) ◽  
pp. 1074-1081 ◽  
Author(s):  
P. Ładyżyński ◽  
J.M. WÓJcicki ◽  
J. Krzymień ◽  
P. Foltyński ◽  
K. Migalska-Musiał ◽  
...  
2009 ◽  
Vol 35 (4) ◽  
pp. 319-327 ◽  
Author(s):  
E. Vandemeulebroucke ◽  
F.K. Gorus ◽  
K. Decochez ◽  
I. Weets ◽  
B. Keymeulen ◽  
...  

2007 ◽  
Vol 27 (6) ◽  
pp. 321-326 ◽  
Author(s):  
N. Dekki ◽  
R. Nilsson ◽  
S. Norgren ◽  
S. M. Rössner ◽  
I. Appelskog ◽  
...  

The aim of this study was to clarify the frequency of patients with type 1 diabetes that have serum that increases pancreatic β-cell cytoplasmic free Ca2+ concentration, [Ca2+]i, and if such an effect is also present in serum from first-degree relatives. We also studied a possible link between the serum effect and ethnic background as well as presence of autoantibodies. Sera obtained from three different countries were investigated as follows: 82 Swedish Caucasians with newly diagnosed type 1 diabetes, 56 Americans with different duration of type 1 diabetes, 117 American first-degree relatives of type 1 diabetic patients with a mixed ethnic background and 31 Caucasian Finnish children with newly diagnosed type 1 diabetes. Changes in [Ca2+]i, upon depolarization, were measured in β-cells incubated overnight with sera from type 1 diabetic patients, first-degree relatives or healthy controls. Our data show that there is a group constituting approximately 30% of type 1 diabetic patients of different gender, age, ethnic background and duration of the disease, as well as first-degree relatives of type 1 diabetic patients, that have sera that interfere with pancreatic β-cell Ca2+-handling. This effect on β-cell [Ca2+]i could not be correlated to the presence of autoantibodies. In a defined subgroup of patients with type 1 diabetes and first-degree relatives a defect Ca2+-handling may aggravate development of β-cell destruction.


2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Osman Son ◽  
Belgin Efe ◽  
Nazan Erenoğlu Son ◽  
Aysen Akalin ◽  
Nur Kebapçi

Objective. The results from Diabetes Control and Complications Trial (DCCT) have propounded the importance of the approach of treatment by medical nutrition when treating diabetes mellitus (DM). During this study, we tried to inquire carbohydrate (Kh) count method’s positive effects on the type 1 DM treatment’s success as well as on the life quality of the patients.Methods. 22 of 37 type 1 DM patients who applied to Eskişehir Osmangazi University, Faculty of Medicine Hospital, Department of Endocrinology and Metabolism, had been treated by Kh count method and 15 of them are treated by multiple dosage intensive insulin treatment with applying standard diabetic diet as a control group and both of groups were under close follow-up for 6 months. Required approval was taken from the Ethical Committee of Eskişehir Osmangazi University, Medical Faculty, as well as informed consent from the patients. The body weight of patients who are treated by carbohydrate count method and multiple dosage intensive insulin treatment during the study beginning and after 6-month term, body mass index, and body compositions are analyzed. A short life quality and medical research survey applied. At statistical analysis,t-test, chi-squared test, and Mann-WhitneyUtest were used.Results. There had been no significant change determined at glycemic control indicators between the Kh counting group and the standard diabetic diet and multiple dosage insulin treatment group in our study.Conclusion. As a result, Kh counting method which offers a flexible nutrition plan to diabetic individuals is a functional method.


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