Midbrain and Spinal Cord Magnetic Resonance Imaging (MRI) Changes in Poliomyelitis

Abstract Background Hemiplegic migraines represent a heterogeneous disorder with various presentations. Hemiplegic migraines are classified as sporadic or familial based on the presence of family history, but both subtypes have an underlying genetic etiology. Mutations in the ATP1A2 gene are responsible for Familial Hemiplegic type 2 (FHM2) or the sporadic hemiplegic migraine (SHM) counterpart if there is no family history of the disorder. Manifestations include migraine with aura and hemiparesis along with a variety of other symptoms likely dependent upon the specific mutation(s) present. Case presentation We report the case of an adult man who presented with headache, aphasia, and right-sided weakness. Workup for stroke and various infectious agents was unremarkable during the patient’s extended hospital stay. We emphasize the changes in the Magnetic Resonance Imaging (MRI) over time and the delay from onset of symptoms to MRI changes in Isotropic Diffusion Map (commonly referred to as Diffusion Weighted Imaging (DWI)) as well as Apparent Diffusion Coefficient (ADC). Conclusions We provide a brief review of imaging findings correlated with signs/symptoms and specific mutations in the ATP1A2 gene reported in the literature. Description of the various mutations and consequential presentations may assist neurologists in identifying cases of Hemiplegic Migraine, which may include transient changes in ADC and DWI imaging throughout the course of an attack.

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Voxelwise analysis of conventional magnetic resonance imaging to predict future disability in early relapsing–remitting multiple sclerosis

Multiple Sclerosis Journal ◽

10.1177/1352458512442991 ◽

2012 ◽

Vol 18 (11) ◽

pp. 1585-1591 ◽

Cited By ~ 9

Author(s):

Delphine Wybrecht ◽

Françoise Reuter ◽

Wafaa Zaaraoui ◽

Anthony Faivre ◽

Lydie Crespy ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Multiple Sclerosis ◽

Magnetic Resonance ◽

Physical Disability ◽

Conventional Magnetic Resonance Imaging ◽

Global Approach ◽

Resonance Imaging ◽

Conventional Magnetic Resonance ◽

Magnetic Resonance Imaging Mri ◽

Mri Changes

Background: The ability of conventional magnetic resonance imaging (MRI) to predict subsequent physical disability and cognitive deterioration after a clinically isolated syndrome (CIS) is weak. Objectives: We aimed to investigate whether conventional MRI changes over 1 year could predict cognitive and physical disability 5 years later in CIS. We performed analyses using a global approach (T2 lesion load, number of T2 lesions), but also a topographic approach. Methods: This study included 38 patients with a CIS. At inclusion, 10 out of 38 patients fulfilled the 2010 revised McDonald’s criteria for the diagnosis of multiple sclerosis. Expanded Disability Status Scale (EDSS) evaluation was performed at baseline, year 1 and year 5, and cognitive evaluation at baseline and year 5. T2-weighted MRI was performed at baseline and year 1. We used voxelwise analysis to analyse the predictive value of lesions location for subsequent disability. Results: Using the global approach, no correlation was found between MRI and clinical data. The occurrence or growth of new lesions in the brainstem was correlated with EDSS changes over the 5 years of follow-up. The occurrence or growth of new lesions in cerebellum, thalami, corpus callosum and frontal lobes over 1 year was correlated with cognitive impairment at 5 years. Conclusion: The assessment of lesion location at the first stage of multiple sclerosis may be of value to predict future clinical disability.

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Magnetic Resonance Imaging of Spinal Cord Disease of Childhood

PEDIATRICS ◽

10.1542/peds.78.2.251 ◽

1986 ◽

Vol 78 (2) ◽

pp. 251-256

Author(s):

Roger J. Packer ◽

Robert A. Zimmerman ◽

Leslie N. Sutton ◽

Larissa T. Bilaniuk ◽

Derek A. Bruce ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Spinal Cord ◽

Magnetic Resonance ◽

Vertebral Body ◽

Congenital Anomalies ◽

Correct Diagnosis ◽

Surface Coil ◽

Resonance Imaging ◽

Spinal Cord Disease ◽

Magnetic Resonance Imaging Mri

Correct diagnosis of spinal cord disease in childhood is often delayed, resulting in irreversible neurologic deficits. A major reason for this delay is the lack of a reliable means to noninvasively visualize the spinal cord. Magnetic resonance imaging (MRI) should be useful in the evaluation of diseases of the spinal cord. A 1.5 Tesla MRI unit with a surface coil was used to study 41 children, including eight patients with intrinsic spinal cord lesions, eight patients with masses compressing the cord, 12 patients with congenital anomalies of the cord or surrounding bony structures, three patients with syrinxes, and three patients with vertebral body abnormalities. Intrinsic lesions of the cord were well seen in all cases as intrinsic irregularly widened, abnormally intense cord regions. MRI was helpful in following the course of disease in patients with primary spinal cord tumors. Areas of tumor were separable from syrinx cavities. Extrinsic lesions compressing the cord and vertebral body disease were also well visualized. Congenital anomalies of the spinal cord, including tethering and lipomatous tissue, were better seen on MRI than by any other radiographic technique. MRI is an excellent noninvasive "screening" technique for children with suspected spinal cord disease and may be the only study needed in many patients with congenital spinal cord anomalies. It is also an excellent means to diagnose and follow patients with other forms of intra- and extraspinal pathology.

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Advanced magnetic resonance imaging (MRI) techniques of the spine and spinal cord in children and adults

Insights into Imaging ◽

10.1007/s13244-018-0626-1 ◽

2018 ◽

Vol 9 (4) ◽

pp. 549-557 ◽

Cited By ~ 12

Author(s):

M. I. Vargas ◽

B. M. A. Delattre ◽

J. Boto ◽

J. Gariani ◽

A. Dhouib ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Spinal Cord ◽

Magnetic Resonance ◽

Resonance Imaging ◽

Magnetic Resonance Imaging Mri

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Current advances in magnetic resonance imaging (MRI) in spinal cord trauma: review article

Spinal Cord ◽

10.1038/sc.1992.74 ◽

1992 ◽

Vol 30 (5) ◽

pp. 305-316 ◽

Cited By ~ 6

Author(s):

M Perovitch ◽

S Perl ◽

H Wang

Keyword(s):

Magnetic Resonance Imaging ◽

Spinal Cord ◽

Magnetic Resonance ◽

Review Article ◽

Spinal Cord Trauma ◽

Resonance Imaging ◽

Magnetic Resonance Imaging Mri

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Magnetic Resonance Imaging ( MRI ) Spinal Cord and Canal Measurements in Normal Dogs

Anatomia Histologia Embryologia ◽

10.1111/ahe.12045 ◽

2013 ◽

Vol 43 (1) ◽

pp. 36-41 ◽

Cited By ~ 8

Author(s):

S. Hecht ◽

M. M. Huerta ◽

R. B. Reed

Keyword(s):

Magnetic Resonance Imaging ◽

Spinal Cord ◽

Magnetic Resonance ◽

Resonance Imaging ◽

Magnetic Resonance Imaging Mri

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A comparison of magnetic resonance imaging sequences in evaluating pathological changes in the canine spinal cord

Polish Journal of Veterinary Sciences ◽

10.2478/v10181-011-0072-1 ◽

2011 ◽

Vol 14 (3) ◽

pp. 481-484 ◽

Cited By ~ 2

Author(s):

Z. Adamiak ◽

A. Pomianowski ◽

Y. Zhalniarovich ◽

M. Kwiatkowska ◽

M. Jaskólska ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Spinal Cord ◽

Magnetic Resonance ◽

Spin Echo ◽

Fast Spin Echo ◽

Spinal Diseases ◽

Pathological Changes ◽

Resonance Imaging ◽

Scanning Time ◽

Magnetic Resonance Imaging Mri

A comparison of magnetic resonance imaging sequences in evaluating pathological changes in the canine spinal cord This paper discusses 28 canine patients subjected to low-field magnetic resonance imaging (MRI) of the spinal cord for neurological indications. The authors describe and compare the used MRI sequences with an indication of the most effective sequences in MRI examinations that require short scanning time. The most effective sequences supporting a quick diagnosis of spinal diseases in dogs were SE (spin echo), FSE (fast spin echo) and 3D HYCE (hybrid contrast enhancement).

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MRI features in the non-traumatic spinal cord injury patients presenting at the Korle Bu Teaching Hospital, Accra

Ghana Medical Journal ◽

10.4314/gmj.v52i3.4 ◽

2018 ◽

Vol 52 (3) ◽

pp. 127-132

Author(s):

Hafisatu Gbadamosi ◽

Yaw B. Mensah ◽

Samuel Asiamah

Keyword(s):

Magnetic Resonance Imaging ◽

Spinal Cord ◽

Spinal Cord Injury ◽

Magnetic Resonance ◽

Spinal Metastases ◽

Traumatic Spinal Cord Injury ◽

Resonance Imaging ◽

Mri Features ◽

Cord Injury ◽

Magnetic Resonance Imaging Mri

Background: Neurological limb deficit due to non-traumatic myelopathy is a disabling and distressing neurological condition. In recent time Magnetic Resonance Imaging (MRI) has proven to be the ultimate imaging modality for evaluating pathologies of the spinal cord.Objective: To describe the Magnetic Resonance Imaging (MRI) features of patients with Non-Traumatic Spinal Cord Injury evaluated at the Korle Bu Teaching Hospital.Methods: A descriptive cross-sectional study was carried out at the Korle Bu Teaching Hospital (KBTH), Accra, Ghana. Results: Out of a total of 141 MRI’s evaluated 60.3% were males and 39.7% female. The majority of the respondents 85.1% had paraparesis/paraplegia,13.5% had quadriparesis/quadriplegia, 1.4% had weakness in one upper limb and both lower limbs. The commonest MRI features of NTSCI recorded was due to degenerative disease of the spine 75.9%, spinal metastases 5.7%, Pott's/pyogenic spondylitis 3.5%, demyelinating disease 2.8% and primary spinal tumours 2.8%.Conclusion: The commonest MRI findings in the study population were due to degenerative disease of the spine, followed by spinal metastases and infective spondylitis. Funding: Not declaredKeywords: paraparesis, paraplegia, tetraparesis, tetraplegia, Magnetic Resonance Imaging

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