Comments on: Mechanistic modeling of rodent liver tumor promotion at low levels of exposure: an example related to dose-response relationships for 2,3,7,8-tetra-chlorodibenzo-p-dioxin (by Andersen ME and Conolly RB)

1998 ◽  
Vol 17 (12) ◽  
pp. 713-713
Author(s):  
Tom Downs ◽  
Ralph Frankowski
Keyword(s):  
Dose Response ◽  
Liver Tumor ◽  
Tumor Promotion ◽  
Mechanistic Modeling ◽  
Low Levels

The Orphan Nuclear Receptor Constitutive Active/Androstane Receptor Is Essential for Liver Tumor Promotion by Phenobarbital in Mice

2004 ◽  
Vol 64 (20) ◽  
pp. 7197-7200 ◽  
Author(s):  
Yukio Yamamoto ◽  
Rick Moore ◽  
Thomas L. Goldsworthy ◽  
Masahiko Negishi ◽  
Robert R. Maronpot
Keyword(s):  
Nuclear Receptor ◽  
Liver Tumor ◽  
Tumor Promotion ◽  
Orphan Nuclear Receptor

Choline Deficiency, Lipid Peroxidation, Liver Cell Surface Receptor Alterations and Liver Tumor Promotion

1988 ◽  
pp. 591-599
Author(s):  
Hishashi Shinozuka ◽  
Chhanda Gupta ◽  
Atsuo Hattori ◽  
James M. Betschart ◽  
Mohamed A. Virji
Keyword(s):  
Lipid Peroxidation ◽  
Cell Surface ◽  
Liver Cell ◽  
Liver Tumor ◽  
Tumor Promotion ◽  
Cell Surface Receptor ◽  
Choline Deficiency ◽  
Surface Receptor

scholarly journals Altered expression of GADD45 genes during the development of chemical-mediated liver hypertrophy and liver tumor promotion in rats

2011 ◽  
Vol 36 (5) ◽  
pp. 613-623 ◽  
Author(s):  
Shogo Ozawa ◽  
Toshie Gamou ◽  
Wataru Habano ◽  
Kaoru Inoue ◽  
Midori Yoshida ◽  
...  
Keyword(s):  
Liver Tumor ◽  
Tumor Promotion ◽  
Altered Expression

Letter To The Editor

PEDIATRICS ◽  
1978 ◽  
Vol 62 (5) ◽  
pp. 862-863
Author(s):  
P. R. J. Burch
Keyword(s):  
Dose Response ◽  
Maternal Smoking ◽  
Linear Dose ◽  
Letter To The Editor ◽  
Low Levels ◽  
Newborn Size

Dr. Garn and his colleagues have found a crudely linear "dose-response" relation between maternal smoking and various measures of newborn size and prematurity. I regret I cannot agree with them that their findings stretch a constitutional explanation to the uttermost. We can distinguish at least two types of smoker: the so-called social or nonconstitutional smoker and the habituated or constitutional smoker. At low levels of smoking the former type will predominate, but at high levels the latter will.

A multivariate approach to plant mineral nutrition: dose–response relationships and nutrient dominance in factorial experiments

1985 ◽  
Vol 63 (12) ◽  
pp. 2138-2143 ◽  
Author(s):  
G. R. Shaver ◽  
M. J. Lechowicz
Keyword(s):  
Dose Response ◽  
Nutrient Content ◽  
N Fertilization ◽  
Mineral Elements ◽  
P Fertilization ◽  
Canonical Variates Analysis ◽  
Canonical Variates ◽  
Low Levels ◽  
High Fertilization ◽  
K Fertilization

Canonical variates analysis was used to compare the effects of fertilization on the concentrations of five mineral elements (N, P, K, Ca, and Mg) in young shoot tissues of six tundra plant species of three different growth forms. There were two specific objectives: (i) to determine whether it was possible to describe meaningful dose–response relationships in a multivariate response to fertilization, and (ii) to determine the multivariate effect of N plus P fertilization in comparison with the effects of N or P added alone. The results showed that low levels of N–P–K fertilization caused a shift in multivariate nutrient content that was intermediate between the control values and the shift caused by high fertilization, and in the same direction as the latter. In a June harvest, the effect of N plus P fertilization was very similar to the effect of N fertilization alone. However, in August the N plus P effect was dominated by the response to P alone. In all of the analyses, the fundamental similarities and differences among unfertilized plants of each species and growth form were maintained under fertilization.

60 Role of apoptosis in liver tumor promotion

2003 ◽  
Vol 144 ◽  
pp. s19
Author(s):  
W. Bursch ◽  
B. Grasl-Kraupp ◽  
U. Wastl ◽  
M. Chabicovsky ◽  
W. Parzefall ◽  
...  
Keyword(s):  
Liver Tumor ◽  
Tumor Promotion
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